Behavioral and subjective effects of D-amphetamine and modafinil in healthy adults.

Modafinil is indicated for the management of excessive daytime sleepiness; however, recent studies have examined a broad range of potential uses. Given that clinical uses of modafinil may be expanding, this study compared modafinil and d-amphetamine effects on subjective and performance measures. Across 11 sessions, 11 healthy adults were tested after oral doses of placebo (5 sessions), modafinil (1.75 mg/kg, 3.50 mg/kg, or 7.00 mg/kg), and d-amphetamine (0.035 mg/kg, 0.070 mg/kg, 0.140 mg/kg) under double-blind, randomized conditions. Assessments of cognitive performance and subjective effects were completed before drug administration, 30 min after drug administration, and at hourly intervals after drug administration for 5 hr. Modafinil increased ratings on the Amphetamine and Morphine Benzedrine Group scales of the Addiction Research Center Inventory (ARCI) and increased ratings on the Vigor and Total Positive scales of the Profile of Mood States. d-Amphetamine increased visual analog ratings of feeling stimulated and liking the drug and increased ratings on the Morphine Benzedrine Group scale of the ARCI. Both medications significantly reduced visual analog scale ratings of feeling sleepy, and modafinil decreased ratings on the ARCI Pentobarbital-Chlorpromazine-Alcohol Group scale. Both medications sustained performance that deteriorated across time on the Sternberg Number Recognition Test. Modafinil also enhanced performance rate on the Digit-Symbol Substitution Task above baseline levels and increased response rate on the Repeated Acquisition of Response Sequences Task. These results suggest that modafinil engenders alerting effects and increases performance in healthy non-sleep-deprived individuals comparable with that of d-amphetamine. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Symmetric BEM formulations for 2-D steady-state and transit potential problems

This paper presents a new concept for symmetric boundary element method (SBEM) applicable to 2-D steady-state and transit potential problems. Two kinds of SBEM formulations are derived. Symmetry is obtained simply through matrix manipulation, and no hypersingularity appears. Therefore, SBEM is much easier than the traditional symmetric Galerkin BEM. Compared with the traditional asymmetric BEM, the present SBEM can reduce the computational cost for time domain problems only. However, when applied to BEM/FEM coupling procedure, SBEM can reduce the computational cost for both steady-state and time domain problems. Three numerical examples are included to illustrate the effectiveness and accuracy of the present formulations.     

文25东复杂断块油藏剩余油分布研究

通过影响剩余油的地质因素分析和油藏数值模拟，查明了文25东复杂断块油藏剩余油分布规律，认为注采井网不完善区、物性相对较差的油层分布区、层位及储层层内的非均质性造成的水动力滞留区及构造高部位和局部断层影响的水动力滞留区均是剩余油分布有利区，在此基础上．制定了相应的挖潜措施，取得了明显的效果。     

集团变分法(CVM)及其在合金相图计算中的应用

介绍了集团变分法的集团概率变量、配置熵等统计分析的理论基础及Helmholtz自由能的描述模型.提出了巨势及相对化学势的几何分析理论.讨论了应用集团变分法和巨势分析理论进行相平衡计算的过程,并分析了同结构平衡相图计算的若干实例.     

视觉诱发脑电波的时变最优滤波估计

本文提出了一个自修正的非平稳信号模型,并设计了时变最优滤波器于视觉诱发脑电波 的估计.估计出的信号与原始信号的各波峰潜伏期严格保持一致,而波峰幅值略有衰减.给 出的仿真与实体试验结果都证明了本方法的有效性.     

关于气井产能、气田稳产特征和气区开采潜力的探讨

根据气田开发特点和国内外开发实践，对气田平均产能评价方法、开发速度与稳产的关系以及气区开采潜力等问题进行了探讨，以提高开发评价、开发建设及投资决策的科学性与可靠性，达到高效开发和稳定供气的目的。分析评价了国内外常用的6种气井产能评价方法，指出了其适用条件。利用中国、土库曼斯坦和俄罗斯部分开发历史较长的气田开发实例分析了开发速度与稳产的关系，结果表明四川裂缝系统稳产情况最好，而土库曼斯坦气田稳产关系最差。利用俄罗斯已枯竭老气区、正在开发的大型主力气区以及中国四川开采历史较长气区的开发实例，对气区开采潜力进行综合分析和探讨，认为在预测气田（或气区）的开发潜力、稳定供气水平和年限时，要全面评价、预计尚未探明储量的规模、质量、投产时间、投产顺序以及储量的可信度和可靠性，以降低开发决策的风险，提高中、长期开发规划的科学性。图5表2参10     

安徽油区挖潜潜力分析

安徽油区为一系列构造成因的小断块群组成,构造演化与沉积背景特征决定了成藏模式。区内构造破碎,断块面积小,储层“三低”特征明显,挖潜难度大。从油藏成因入手,依据对油气运聚成藏规律的认识和勘探开发实践中取得的实际资料,通过对已发现的含油断块储油丰度与相关地质因素之间的关系分析,从垂向和横向上进一步认识油气分布规律,探索老区挖潜方向,找出可能具有潜在挖潜价值的潜力区,以增强老区增储上产能力。     

A BOUNDARY INTEGRAL EQUATION AND ITS NUMERICAL SOLUTION OF POTENTIAL FLOW AROUND SURFACE-IRREGULA-RITIES

In this paper,using complex functional theory,the authors turn the potentialflow around the surface irregularities in a pressure conduit and semi-infinite platforms intoDirichlet problem.Based on Schwarz formula and by the application of Plemelj's formula,theauthors change the problem into the integration of a Cauchy boundary integral equation in theflow plane through the substitution of variables.Using numerical integration,the authors obtainthe velocity distribution and pressure coefficient along surface irregularities and platforms.Thephysical concept of this method is clear,the convergent speed is rapid and the computative effi-ciency is high.The calculated values agree well with the measured results.It is an effective andsimple method in solving potential flow.     

波在PTL介质中传播的旅行时反演

本文对Byun(1990)的横向各向同性介质的旅行时反演方法作了两点改进:其一是根据优化后的V_r值计算一个初始的F值,然后再根据这个初始值进行最小均方误差分析;其二是对初始值进行优化分析时,提出用测量值(或由式(4)和式(10)计算的理论值)作为实际值进行拟合,而Byun的方法是用式(11)的计算来得到一个实际值。理论模型证明:本文所述方法有一个比较宽的适应性,而Byun方法只在弱各向异性时才可以得到较精确的结果。     

Extraction of Singular Points from Dense Motion Fields: An Analytic Approach

In this paper we propose a new method to extract the vortices, sources, and sinks from the dense motion field preliminary estimated between two images of a fluid video. This problem is essential in meteorology for instance to identify and track depressions or convective clouds in satellite images. The knowledge of such points allows in addition a compact representation of the flow which is very useful in both experimental and theoretical fluid mechanics. The method we propose here is based on an analytic representation of the flow. This approach has the advantage of being robust, simple, fast and requires few parameters.