复杂构造叠后逆时深度偏移

本文从三维波动方程出发，导出了用于三维叠后逆时偏移的无层间反 波动方程，并给出了其数虎法和稳定性条件。     

柴达木盆地北缘侏罗系烃源岩干酪根13C核磁共振研究

柴达木盆地北缘是柴达木盆地三大油气区之一,其源岩为早、中侏罗世煤系地层.烃源岩有机质类型以Ⅲ₁型和Ⅱ型干酪根为主,Ⅰ₂型干酪根仅在局部地区有分布.通过对柴达木盆地北缘侏罗系烃源岩中不同类型干酪根的¹³C核磁共振研究,指出了研究区Ⅰ₂、Ⅱ、Ⅲ₁型干酪根的化学结构特征以及化学结构中“芳构碳”、“油潜力碳”与“气潜力碳”的相对含量,据此从定量分析的角度对不同类型干酪根的生油气贡献作了评价.Ⅰ₂、Ⅱ、Ⅲ₁型干酪根的生烃能力依次减弱,对生油的贡献也依次减弱,且生成油气的比例不同,Ⅰ₂、Ⅱ型干酪根以生油为主,Ⅲ₁型干酪根则以生气为主.     

基于波动方程的聚焦点控制照明叠前深度偏移

 基于波动方程的聚焦点控制照明叠前深度偏移技术借助于差分计算，把速度、密度等介质参数的影响体现在差分计算的矩阵方程中，能够自动适应速度场的任意变化，快速傅里叶变换的使用也加速了波场延拓的计算速度。因此此法兼具有限差分偏移方法和傅里叶偏移方法的优点，既可适应速度场的剧烈变化，又可保证对陡倾地层的成像效果，是目前针对复杂构造最有效的成像方法之一。对于单个聚焦点及其周围的成像步骤为：①采用矩形网格情况下绕射走时的有限差分计算方法生成合成算子；②应用合成算子来合成面炮震源和面波记录；③对合成的面炮震源和面波记录做傅里叶有限差分法波动方程叠前深度偏移，得到该聚焦点及其附近区域的成像结果。按照上述成像步骤，将震源波场和炮集记录依据相应的外推公式进行延拓，最终应用成像条件求取成像值。在地质目标处选取多个聚焦点，可以得到面向目标的控制照明偏移成像，在多个层位上选取多个聚焦点进行控制照明叠前深度偏移，可以得到整块区域的成像。通过对Marmousi模型的试算，取得了较好的效果。     

莺歌海盆地底辟构造的成因及石油地质意义

在总结莺歌海盆地底辟构造特征及其伴生的温度和压力异常资料的基础上,提出了流体底辟模式,并进一步讨论了流体底辟在石油地质中的意义.     

Compressive sensing SAR range compression with chirp scaling principle

Compressive sensing(CS) techniques offer a framework for the detection and allocation of sparse signal with a reduced number of measurements.This paper proposes a novel SAR range compression,namely compressive sensing with chirp scaling(CS-CS),achieving the same range resolution as conventional SAR approach,while using fewer range samplings.In order to realize accurate range cell migration correction(RCMC),chirp scaling principle is used to construct reference matrix for compressive sensing recovery.Additionally,error diagrams are designed for measurement of the performance of CS-CS,and some experiments of using real data are performed to deal with the errors caused by three conditions:SNR,sparsity and sampling.     

海量数据库迁移与升级

目前数据库中数据越来越多,应用对数据库在线时间的要求也越来越高,使得数据库迁移和数据库升级成为了一件非常困难的事情.为此,介绍了几种迁移和升级的方法,用以实现以尽可能少的停机时间对TB级数据库完成数据库的迁移和升级.     

Regulation of Neutrophil Functions by Hv1/VSOP Voltage-Gated Proton Channels

The voltage-gated proton channel, Hv1, also termed VSOP, was discovered in 2006. It has long been suggested that proton transport through voltage-gated proton channels regulate reactive oxygen species (ROS) production in phagocytes by counteracting the charge imbalance caused by the activation of NADPH oxidase. Discovery of Hv1/VSOP not only confirmed this process in phagocytes, but also led to the elucidation of novel functions in phagocytes. The compensation of charge by Hv1/VSOP sustains ROS production and is also crucial for promoting Ca²⁺ influx at the plasma membrane. In addition, proton extrusion into neutrophil phagosomes by Hv1/VSOP is necessary to maintain neutral phagosomal pH for the effective killing of bacteria. Contrary to the function of Hv1/VSOP as a positive regulator for ROS generation, it has been revealed that Hv1/VSOP also acts to inhibit ROS production in neutrophils. Hv1/VSOP inhibits hypochlorous acid production by regulating degranulation, leading to reduced inflammation upon fungal infection, and suppresses the activation of extracellular signal-regulated kinase (ERK) signaling by inhibiting ROS production. Thus, Hv1/VSOP is a two-way player regulating ROS production. Here, we review the functions of Hv1/VSOP in neutrophils and discuss future perspectives.     

Deciphering the Binding Interactions between Acinetobacter baumannii ACP and β-ketoacyl ACP Synthase III to Improve Antibiotic Targeting Using NMR Spectroscopy

Fatty acid synthesis is essential for bacterial viability. Thus, fatty acid synthases (FASs) represent effective targets for antibiotics. Nevertheless, multidrug-resistant bacteria, including the human opportunistic bacteria, Acinetobacter baumannii, are emerging threats. Meanwhile, the FAS pathway of A. baumannii is relatively unexplored. Considering that acyl carrier protein (ACP) has an important role in the delivery of fatty acyl intermediates to other FAS enzymes, we elucidated the solution structure of A. baumannii ACP (AbACP) and, using NMR spectroscopy, investigated its interactions with β-ketoacyl ACP synthase III (AbKAS III), which initiates fatty acid elongation. The results show that AbACP comprises four helices, while Ca²⁺ reduces the electrostatic repulsion between acid residues, and the unconserved F47 plays a key role in thermal stability. Moreover, AbACP exhibits flexibility near the hydrophobic cavity entrance from D59 to T65, as well as in the α₁α₂ loop region. Further, F29 and A69 participate in slow exchanges, which may be related to shuttling of the growing acyl chain. Additionally, electrostatic interactions occur between the α₂ and α₃-helix of ACP and AbKAS III, while the hydrophobic interactions through the ACP α₂-helix are seemingly important. Our study provides insights for development of potent antibiotics capable of inhibiting A. baumannii FAS protein–protein interactions.