表面等离子体共振传感检测方法研究

为了找到表面等离子体共振(SPR)检测物体的最佳方法,基于SPR,通过Matlab进行了一系列仿真。对检测物质的可行性进行了讨论,得出SPR能在一定范围内检测物质。对影响SPR现象的因素进行了仿真,得出达到最佳共振效果的参数值。分别对角度调制和波长调制方法进行仿真比较,分析了二者检测不同折射率样品的可行性和特点,选择出了较佳的检测方法。结果得出:达到最佳共振效果的参数值是金膜厚度为45 nm,入射光波长为632.8 nm,棱镜折射率根据实验条件和样品综合选定。角度和波长调制均能较好地检测不同折射率的样品,角度调制检测分辨率低于波长调制。     

2-(5-溴-2-噻唑偶氮)-5-二乙氨基苯酚的合成与结构分析

用2-氨基噻唑为原料经溴化和重氮化,与N,N-二乙基间氨基苯酚偶联,合成了新有机分析试剂2-(5-溴-2-噻唑偶氮)-5-二乙氨基苯酚〔2-(5-Bromo-2-thiazolylazo)-5-diethylaminophenol,简称5-Br-TADAP〕.用薄层色谱法、元素分析法、质谱法、红外吸收光谱法、核磁共振谱法和可见吸收光谱法等分析手段对产品进行了分析和结构鉴定.该试剂至今未见文献报导.     

基于表面等离子体共振传感器的尿微量白蛋白检测

检测尿微量白蛋白(MAU)可对轻微肾脏损害进行早期诊断,也可对高血压患者可能发生的心脑血管事件进行预测。实验将抗体通过巯基自组装固定于Au膜表面,研制了一种快速检测MAU的表面等离子体共振(SPR)生物传感器。结果表明:直接检测法可以检测到0.3μg/L的MAU,而纳米Au放大法检测限可以低至0.03μg/L。     

掺锰BaTiO3 PTCR陶瓷的电子顺磁共振研究

利用电子顺磁共振（EPR）方法对Mn掺杂的BaTiO3 PTCR陶瓷在120－450K的温度范围内进行了研究，研究结果表明：高自旋Mn^2 离子的6重谱线非常明显，表征谱线位置的g因子为2．009 9,Mn^2 离子信号弱弱与BaTiO3晶体结构密切相关，Mn^2 离子信号的温度分布呈U型，即在三方相和立方相时，信号强度较强，而在四方相和斜方相时信号很弱，这是因为在四方相和斜方相中，由于BaTiO3晶体结构的扭曲和畸变，导致Mn^2 和Vo空位缔合生成Mn^2 -Vo复合缺陷，未成对电子的消失以及复合缺陷n^2 -Vo的生成最Mn^2 在四方相和斜方相（200－380K）消失的主因，实验中没有发现Mn^3 和Mn^4 的信号，而与实验的环境条件一致，掺Mn后样品Curie点的漂移可能是Mn进入晶格的一个判据，此外，由于试样的n(Ba)/n(Ti)=1，因而没有发现钡空位VBa及其它的复合缺陷（如：VBa-Mn^2 ,Mn^3 -Vo,La^3 -Mn^3 等），Mn^2 离子等电子陷阱的生长是Curie温度处电阻骤然增加的主要原因。     

Study of alinite cement hydration by impedance spectroscopy

Two types of alinite cements, Mg-alinite and Zn-alinite, were synthesized using the reagent grade chemicals. Their hydration behavior was compared with ordinary Portland cement (OPC) using impedance spectroscopy (IS) and ²⁹Si nuclear magnetic resonance (NMR) spectroscopy. The bulk resistance in the IS spectra and the intensity ratio of the hydrous (Q₁ and Q₂) to anhydrous (Q₀) phases in the NMR spectra were estimated as the extent of hydration. The results obtained from both techniques were consistent each other. Mg-alinite had a comparable hydration rate to OPC and Zn-alinite exhibited faster hydration kinetics than Mg-alinite.     

Ru-doped nanostructured carbon films

Pure and Ru-doped carbon films are deposited on Si (100) substrates by electron cyclotron resonance chemical vapor deposition. The films are characterized by transmission electron microscopy, electron energy loss spectroscopy, energy dispersive X-ray spectroscopy and atomic force microscopy. In both the pure and Ru-doped samples, diamond nanocrystallites are formed in amorphous carbon matrices. The Ru-doped film contains much smaller diamond nanocrystallites (approx. 3 nm) than the pure samples (approx. 11 nm). Lower surface roughnesses are observed in both pure and Ru-doped samples as compared to other reported nanocrystalline diamond films. The conductivity of the Ru-doped film is significantly higher than that of the pure film. The results show that Ru-doped nanocrystalline diamond films have unique structures and properties as compared to pure nanocrystalline diamond films or metal doped diamond-like carbon films, which may offer advantages for electrochemical, optical-window, field emission or tribological applications.     

几种光谱方法(FTIR、FT-Raman,NMR)在橡胶分析中的应用

综述了傅里叶变换红外光谱 ,傅里叶变换拉曼光谱以及核磁共振波谱在橡胶结构的定性、定量分析中的应用     

用固体核磁技术分析PE 100管材料的抗熔垂性

用固体核磁技术分析了2种具有不同抗熔垂性能的聚乙烯管材料的凝聚态结构与流变性能。管材树脂的抗熔垂性能与其核磁迟豫特性紧密相关,好的抗熔垂性能对应更长的纵向迟豫时间。抗熔垂性能好的双峰管材料的重均分子量更高,高相对分子质量部分的含量更多。     

Synthesis and characterization of soluble (porphyrinato)iron(II) polymers

The use of (tetrakis(4-hexylphenyl)porphyrinato)Fe(II) in polymerization reactions with bidentate ligands such as 9,10-diisocyanoanthracene and 1,4-diisocyanobenzene led to well-defined stacked polymers1 and2 which are still soluble in common organic solvents such as chloroform, dichloromethane, and tetrahydrofurane. They have been completely characterized by¹H-NMR and UV/vis spectropscopy in solution, even allowing end-group analysis for determination of the average degree of polymerization, yieldingn=10 andn=5 for1 and2, respectively. Mößbauer and IR spectroscopy further established the strong Fe-CN bonding reflected by very small isomer shifts and quadrupole splittings (E _Q0.2 mm s^–1) and a large decrease in the IR stretching frequency (v _CN60 cm^–1). The axially stacked polymers exhibit semiconducting properties only upon doping.Presented at the 5th International Symposium on Macromolecule-Metal Complexes (MMV), Summer 1993 in Bremen, Germany.     

Surface plasmon resonance evaluation of various aminoglycoside-RNA hairpin interactions reveals low degree of selectivity

Aminoglycoside antibiotics, which are able to selectively bind to RNA, are considered to be an important lead in RNA-targeting drug discovery. In this study, surface plasmon resonance (SPR) was employed to explore the interaction of aminoglycosides with known tobramycin-binding RNA hairpins (aptamers) and an unrelated RNA hairpin. It was established that aminoglycosides have multiple interactions with RNA hairpins. Unexpectedly, the different hairpins showed comparable affinity for a set of related aminoglycosides. The observed absence of selectivity presents an extra hurdle in the discovery of novel aminoglycosides as specific drugs that target defined RNA hairpins.