Contrast‐enhanced wide‐angle high‐speed polarization modulator for active‐retarder 3‐D displays

Abstract— A contrast‐enhanced wide‐angle high‐speed polarization modulator for active‐retarder 3‐D displays is proposed. By using a double liquid‐crystal‐cell structure together with a dedicated driving scheme and an external quarter‐wave retarder, a high‐performance modulator can be realized, resulting in minimized brightness loss and low cross‐talk levels in fast‐refresh time‐multiplexed 3‐D displays.     

Fast full‐color reflective display via photoluminescent enhancement

Reflective displays are advantageous in applications requiring low power or daylight readability. However, there are no low‐cost reflective technologies capable of displaying bright colors. By employing photoluminescence to more efficiently use ambient light, we created a prototype display that provides bright, full color in a simple, low‐cost architecture. This prototype includes a novel electrokinetic shutter, a layer that incorporates patterned luminescent red, green, and blue sub‐pixel elements, and a novel optical out‐coupling scheme. The luminescent elements convert otherwise‐wasted portions of the incident spectrum to light in the desired color band, resulting in improved color saturation and lightness. This prototype provides a color gamut that is superior to competing reflective display technologies that utilize color filters in single‐layer side‐by‐side sub‐pixel architectures. The current prototype is capable of switching in <0.5 s; future displays based on an alternative electro‐optic shutter technology should achieve video rate operation. A transflective version of this technology has also been prototyped. The transflective version utilizes its backlight with a power efficiency that is at least three times that of a conventional liquid crystal display. These photoluminescence‐based technologies enable a host of applications ranging from low‐power mobile products and retail pricing signage to daylight readable signage for outdoor advertising segments.     

Mutant p53 Mediates Sensitivity to Cancer Treatment Agents in Oesophageal Adenocarcinoma Associated with MicroRNA and SLC7A11 Expression

TP53 gene mutations occur in 70% of oesophageal adenocarcinomas (OACs). Given the central role of p53 in controlling cellular response to therapy we investigated the role of mutant (mut-) p53 and SLC7A11 in a CRISPR-mediated JH-EsoAd1 TP53 knockout model. Response to 2 Gy irradiation, cisplatin, 5-FU, 4-hydroxytamoxifen, and endoxifen was assessed, followed by a TaqMan OpenArray qPCR screening for differences in miRNA expression. Knockout of mut-p53 resulted in increased chemo- and radioresistance (2 Gy survival fraction: 38% vs. 56%, p < 0.0001) and in altered miRNA expression levels. Target mRNA pathways analyses indicated several potential mechanisms of treatment resistance. SLC7A11 knockdown restored radiosensitivity (2 Gy SF: 46% vs. 73%; p = 0.0239), possibly via enhanced sensitivity to oxidative stress. Pathway analysis of the mRNA targets of differentially expressed miRNAs indicated potential involvement in several pathways associated with apoptosis, ribosomes, and p53 signaling pathways. The data suggest that mut-p53 in JH-EsoAd1, despite being classified as non-functional, has some function related to radio- and chemoresistance. The results also highlight the important role of SLC7A11 in cancer metabolism and redox balance and the influence of p53 on these processes. Inhibition of the SLC7A11-glutathione axis may represent a promising approach to overcome resistance associated with mut-p53.     

曹雨微[1],2,刘远2,孔会民1,2,岳萍2,唐大才2,林彦军1,[3]

以MgCl2为晶面调控剂，利用水热法对氢氧化镁（MH）的（001）晶面选择性生长进行调控，研究了晶面调控剂浓度、反应温度、反应时间等因素对MH颗粒的溶解和结晶作用。调控后产品各晶面的XRD衍射峰强度I001/I101和I001/I110较原料分别提高了214.30%和307.45%，百吨级中试产品的I001/I101和I001/I110较原料分别提高了84.08%和112.99%。采用XRD、FE-SEM、TEM、FTIR、粒度分析仪对MH产品的形貌、结构进行了表征，并对调控机理进行了研究。结果表明，MgCl2可以在水热体系中促进MH的（001）晶面选择性生长。一方面，MgCl2作为强酸弱碱盐降低了体系pH值，同时Cl－可以通过电荷中和效应使MH发生进一步加速溶解。另一方面，MgCl2提供的Cl－作用于MH的结晶过程，通过促进MH边缘生长，强化了（001）晶面的生长。     

一种用于14位1.28MS/sΣΔADC的数字抽取滤波器设计

设计了一种数字抽取滤波器,此滤波器由多级级联结构组成,对sigma-delta调制器的输出信号进行滤波和64倍的降采样,具有较小的电路面积和较低的功耗.采用TSMC 0.18μm CMOS工艺实现,工作电压1.8V,流片测试结果表明:sigma-delta调制器输出信号经过数字抽取滤波器后,信噪失真比(SNDR)达到了93.9 dB,满足设计要求.所提出的数字抽取滤波器-6dB带宽为640kHz,抽取后的采样频率为1.28MHz,功耗为33mW,所占面积约为0.4mm×1.7mm.     

光栅光调制器周期结构的优化分析与实验

针对光栅光调制器的光学调制特点,建立一种可变周期结构的光栅光调制器模型,采用Matlab软件中的数字图像处理方法进行研究。利用傅里叶变换分析两种周期结构的光栅光调制器在频谱面和像面的光场分布,并得到不同周期结构对器件调制对比度的影响。实验得到了两种结构像面的光强输出对比。结果表明:不同周期结构对器件的亮态调制效果影响不大;当器件上下反射面中心对齐,下层反射面在器件周期方向两侧各超出上层光栅面的1/2倍光栅间隙宽度时,器件具有最佳的暗态调制效果,从而得到了光栅光调制器的一种周期结构优化方案。     

基于相位调制器倍频技术产生56GHz毫米波的光载无线通信系统

提出并实验研究了一种基于光相位调制器(PM)倍频技术产生56GHz毫米波的光载无线通信(RoF)系统。在中心站,通过28GHz射频(RF)信号驱动PM产生了56GHz光毫米波,并将下行的2.8Gb/s开关键控(OOK)信号调制到该光载波上,然后经过20km标准单模光纤(SSMF)传输至基站,最后由天线进行发射。用户终端接收后,采用相干解调恢复出基带信号。实验结果表明,56GHz光载毫米波信号经SSMF传输20km后其功率代价小于1dB,通过无线方式传输1.1m后其功率代价小于2.5dB。     

马赫—曾德尔电光调制器原理及其在光纤通信中的应用

从电光调制器的物理原理入手,结合马赫-曾德尔干涉结构分析了电光调制器对输入信号光相位和幅值的影响。结合目前高速光纤通信常用的调制码型,分析仿真了全频率归零码、半频率归零码、抑止载波归零码和单边带调制四种调制格式。并对电光调制器中非线性的影响进行了论述。     

SAMPAVE沥青混合料级配设计研究

SAMPAVE(Stress Absorbing Mixtures Pavement)沥青混合料是一种新型的延缓和防止反射裂缝的应力吸收层材料,具有抗裂、防渗、粘结等特性.根据变i法对SAMPAVE混合料进行矿料组成设计,并与AC-5、美国规范、科氏公司推荐的级配范围进行比较.结果表明,对于变i法设计的SAMPAVE混合料,级配上限、级配下限确定的沥青用量在设计工程级配沥青用量的±0.3%范围内,满足生产控制的要求,且SAMPAVE混合料具有优良的耐高温、耐低温、抗变形、耐疲劳、抗水损害等路用性能.     

高等数学教学中反思性教学法的应用

本文以反思性教学理论为指导,深入研究了反思性教学在高等数学教学中的可行性及必要性。通过对反思性教学和高等数学教学之间辨证关系的分析和研究,提出了在高等数学教学中运用反思性教学的一些教学策略。