全方位太阳辐照度测量系统设计

设计一种以DSP为核心的全方位太阳辐照度测量系统,利用安装在云台上的太阳能电池板的转动以获取全方位的太阳辐照度数据。通过对采集到的数据进行分析,既可以测试太阳能电池板在各种安装方式（如平放、斜放和幕墙）下的发电效率,又可对光伏建筑一体化的光伏电站建设方案进行评估,还可在建成之后对光伏电站的发电状态进行管理和监测。     

Group technology based adaptive cell formation using predator-prey genetic algorithm

In recent years, there has been a considerable growth of application of group technology in cellular manufacturing. This has led to investigation of the primary cell formation problem (CFP), both in classical and soft-computing domain. Compared to more well-known and analytical techniques like mathematical programming which have been used rigorously to solve CFPs, heuristic approaches have yet gained the same level of acceptance. In the last decade we have seen some fruitful attempts to use evolutionary techniques like genetic algorithm (GA) and Ant Colony Optimization to find solutions of the CFP. The primary aim of this study is to investigate the applicability of a fine grain variant of the predator-prey GA (PPGA) in CFPs. The algorithm has been adapted to emphasize local selection strategy and to maintain a reasonable balance between prey and predator population, while avoiding premature convergence. The results show that the algorithm is competitive in identifying machine-part clusters from the initial CFP matrix with significantly less number of iterations. The algorithm scaled efficiently for large size problems with competitive performance. Optimal cluster identification is then followed by removal of the bottleneck elements to give a final solution with minimum inter-cluster transition cost. The results give considerable impetus to study similar NP-complete combinatorial problems using fine-grain GAs in future.     

基于小波变换的语音同步方法研究

为提高语音通信干扰效果客观评估中标准语音文件和受扰语音文件的同步精度,对军标GJB4405A-2006中规定的标准语音文件增设了高低频交叉的双音频同步头;介绍了小波消噪的原理,利用2层sym小波对受扰语音文件进行了消噪处理,将同步头中的高频信号作为噪声进行大幅削弱;设计了基于幅度比较的同步算法,找出同步基准点,并对20组受扰严重的语音文件的进行了仿真测试,仿真结果证明了该方法得到的同步精度符合后续数据处理的要求。     

服务器集群负载均衡的建模与仿真研究

研究服务器集群负载优化调试问题,各服务器负载能力差异较大,要求尽可能使每一个服务器的负载均衡,传统方法没有考虑负载动态变化特点,导致服务器集群负载极不均衡,系统性能差。为提高集群系统的整体性能,提出一种基于遗传算法的服务器集群负载均衡算法。首先根据负载均衡目标建立数学模型,然后采用遗传算法模型进行求解。仿真结果表明,遗传算法提高了服务器集群系统吞吐量,使系统负载更加均衡,使整个集群系统的资源得到充分利用。     

用正电子湮没寿命技术研究塑性变形纯Ni的回复过程

本文用正电子湮没寿命方法研究了塑性变形镍(含0.01％杂质)的回复过程的特点及杂质在缺陷回复过程的作用和影响,计算了形变为10％的试样中的位错密度及形成空位团的有效空位浓度。     

立式钻铣床动力头设计与三维造型

多工位钻铣床实现了一台机床对一个零件做不同加工的功能,节省了机床,也缩小了占地面积,同时提高了加工精度和生产率,对工人劳动强度也降低很多。本设计中,钻头的固定采用拉杆式楔形固定,钻头采用套筒及主轴轴面为拉杆的结构,套筒外侧用绝缘胶固定了一个支撑架,钻头的动力由同步齿形带传递到钻头,比起万向轴传递动力要准确且刚性好。动力采用行星轮的传递方式,保证了各工位的同步工作,节省空间,本机构紧凑,各啮合齿轮之间中心距不超过100 mm,因而,用齿轮传动可以满足要求,这样可以用标准件对机床快速装配完工,对缩短加工周期有很大好处。     

Characterization and Reconstitution of Human Lipoyl Synthase (LIAS) Supports ISCA2 and ISCU as Primary Cluster Donors and an Ordered Mechanism of Cluster Assembly

Lipoyl synthase (LIAS) is an iron–sulfur cluster protein and a member of the radical S-adenosylmethionine (SAM) superfamily that catalyzes the final step of lipoic acid biosynthesis. The enzyme contains two [4Fe–4S] centers (reducing and auxiliary clusters) that promote radical formation and sulfur transfer, respectively. Most information concerning LIAS and its mechanism has been determined from prokaryotic enzymes. Herein, we detail the expression, isolation, and characterization of human LIAS, its reactivity, and evaluation of natural iron–sulfur (Fe–S) cluster reconstitution mechanisms. Cluster donation by a number of possible cluster donor proteins and heterodimeric complexes has been evaluated. [2Fe–2S]-cluster-bound forms of human ISCU and ISCA2 were found capable of reconstituting human LIAS, such that complete product turnover was enabled for LIAS, as monitored via a liquid chromatography–mass spectrometry (LC–MS) assay. Electron paramagnetic resonance (EPR) studies of native LIAS and substituted derivatives that lacked the ability to bind one or the other of LIAS’s two [4Fe–4S] clusters revealed a likely order of cluster addition, with the auxiliary cluster preceding the reducing [4Fe–4S] center. These results detail the trafficking of Fe–S clusters in human cells and highlight differences with respect to bacterial LIAS analogs. Likely in vivo Fe–S cluster donors to LIAS are identified, with possible connections to human disease states, and a mechanistic ordering of [4Fe–4S] cluster reconstitution is evident.     

Sensitivity to Cisplatin in Head and Neck Cancer Cells Is Significantly Affected by Patient-Derived Cancer-Associated Fibroblasts

Cancer-associated fibroblasts (CAFs) are one of the most abundant and critical components of the tumor stroma. CAFs can impact many important steps of cancerogenesis and may also influence treatment resistance. Some of these effects need the direct contact of CAFs and cancer cells, while some involve paracrine signals. In this study, we investigated the ability of head and neck squamous cell carcinomas (HNSCC) patient-derived CAFs to promote or inhibit the colony-forming ability of HNSCC cells. The effect of cisplatin on this promoting or inhibiting influence was also studied. The subsequent analysis focused on changes in the expression of genes associated with cancer progression. We found that cisplatin response in model HNSCC cancer cells was modified by coculture with CAFs, was CAF-specific, and different patient-derived CAFs had a different “sensitizing ratio”. Increased expression of VEGFA, PGE2S, COX2, EGFR, and NANOG in cancer cells was characteristic for the increase of resistance. On the other hand, CCL2 expression was associated with sensitizing effect. Significantly higher amounts of cisplatin were found in CAFs derived from patients who subsequently experienced a recurrence. In conclusion, our results showed that CAFs could promote and/or inhibit colony-forming capability and cisplatin resistance in HNSCC cells via paracrine effects and subsequent changes in gene expression of cancer-associated genes in cancer cells.     

再生砖混骨料混凝土柱的小偏心受压性能

通过小偏心受压性能试验对比研究3根的天然骨料混凝土柱和3根同强度全再生砖混骨料混凝土柱,强度分别为C25、C30和C35. 对6根柱进行加载试验,分析再生砖混骨料混凝土柱相比于同强度天然骨料混凝土柱在受力过程、破坏特征、变形能力与承载力等方面的差异. 试验发现,再生砖混骨料混凝土柱在小偏心加载至破坏的过程中,具有与天然骨料混凝土柱相似的3个受力阶段,且符合平截面假定. 与同强度的天然骨料混凝土柱相比,变形较大,但再生砖混骨料混凝土柱的极限承载力略高,原因可能在于两者轴心抗压强度的差异.     

基于数据融合的ABC-SVM社区疾病预测方法

针对现有社区医疗服务中的疾病预测方法存在数据利用率低、疾病分析类型单一、自动化程度差、疾病预测效果不理想等不足,提出在物联网大数据环境下可用于社区医疗的健康数据融合及疾病预测方法. 通过主成分分析(PCA)和聚类分析对社区中居民的生理指标数据进行特征提取;结合人工蜂群(ABC)算法构造支持向量机(SVM)非线性分类器对数据进行特征级融合分析并预测潜在疾病. 实验结果表明,所提方法的疾病识别准确率达到93.10%,相较于传统SVM方法和BP神经网络方法分别提高17.24% 和72.41%. 该方法能够在提高数据利用率、降低计算资源消耗的前提下有效识别多种潜在疾病,可实现疾病早发现、早预防、早治疗;可广泛应用于社区健康管理、老年社区监护甚至临床医疗.