Adults' conceptions of everyday memory failures in others: Factors that mediate the effects of target age.

Investigated young and older adults' conceptions of memory failures in others. 100 young and 100 older adults rated memory failures in targets of 20, 40, 60, and 80 yrs of age as to how likely the memory failures were due to lack of effort or lack of ability. With increasing age, targets' forgetful episodes were rated as less likely to be caused by lack of effort and more likely to be due to lack of ability. A Subject Age?×?Target Age interaction on ability ratings showed age to be more salient for older Ss. Memory content, type of memory, S sex, and target sex all influenced judgment of memory failure. The results support J. T. Erber's (1989) notion of a double standard in memory-failure appraisal; they demonstrated that adults' conceptions of memory include a decremental view of memorial ability with increasing age that is differentially sensitive to S, target, and memorial variables. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Effects of gender, construct type, occupational information, and career relevance on vocational differentiation.

A study was designed to replicate and extend previous research on 1 aspect of vocational structure, vocational differentiation (VOD). Results of a 2 (gender)?×?2 (occupational information)?×?2 (construct type)?×?3 (career relevance) between-Ss study revealed 2 sets of noteworthy findings. First, results replicated previous findings concerning the impact of each of these factors on levels of VOD. Higher levels of VOD were found in men than were found in women and were related to the use of personal constructs when Ss judged highly irrelevant career alternatives. Second, these effects were qualified by interaction between construct type (personal and provided) and career relevance (high, mixed, and low). Personally elicited constructs were used with greater differentiation than were standard provided ones only when participants evaluated highly relevant career alternatives. This effect challenges long-standing assumptions regarding differences between personal and provided vocational constructs, and the implications of this are discussed. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Distributed Processing Involving Personal Computers and Mainframe Hosts

This paper surveys some of the issues involved in building useful distributed systems involving PC's and hosts. Alternative communications techniques for micro-mainframe communication are compared. The point of view is presented that the PC user should be provided with a unified view of the heterogeneous distributed system to which he is connected. The proposed method is to formalize the notion of a service request and provide distributed services by function shipping service requests to remote nodes able to provide the service, e.g., personal computers will ship requests which they cannot satisfy locally to hosts on the network. Providing a unified view of data which allows PC application programs to access files on mainframes is an example of a service which can be built by intercepting and shipping service requests. Examples from current IBM products are used to illustrate approaches. The views presented are the authors' own, based on systems research in progress at the IBM Thomas J. Watson Research Center.     

A highly stable polyethylene glycol-conjugated human single-chain antibody neutralizing granulocyte-macrophage colony stimulating factor at low nanomolar concentration

GM-CSF (granulocyte-macrophage colony stimulating factor) plays a central role in inflammatory processes. Treatment with antibodies neutralizing murine GM-CSF showed significant therapeutic effects in mouse models of inflammatory diseases. We constructed by phage display technology a human scFv, which could potently neutralize human GM-CSF. At first, a human V(L) repertoire was combined with the V(H) domain of a parental GM-CSF-neutralizing rat antibody. One dominant rat/human scFv clone was selected, neutralizing human GM-CSF with an IC50 of 7.3 nM. The human V(L) of this clone was then combined with a human V(H) repertoire. The latter preserved the CDR 3 of the parental rat V(H) domain to retain binding specificity. Several human scFvs were selected, which neutralized human GM-CSF at low nanomolar concentrations (IC50 > or = 2.6 nM). To increase serum half-life, a branched 40 kDa PEG-polymer was coupled to the most potent GM-CSF-neutralizing scFv (3077) via an additional C-terminal cysteine. PEG conjugation had a negligible effect on the in vitro neutralizing potential of the scFv, although it caused a significant drop in binding affinity owing to a reduced on-rate. It also significantly increased the stability of the scFv at elevated temperatures. In mouse experiments, the PEGylated scFv 3077 showed a significantly prolonged elimination half-life of 59 h as compared with 2 h for the unconjugated scFv version. PEGylated scFv 3077 is a potential candidate for development of a novel antibody therapy to treat pro-inflammatory human diseases.     

Reduction in photosynthetic efficiency of Cladophora glomerata,induced by overlying canopies of Lemna spp

The duckweeds Lemna minor L. and L. minuscula Herter reduced PSII quantum efficiency (F'q/F'm) of the filamentous green alga Cladophora glomerata Kützing by up to 42% over seven days when floating above mats of C. glomerata in containers. Dissolved oxygen (DO) increased by 23% at 30 degrees C in containers with C. glomerata over controls. But when the water surface in the containers was covered with Lemna spp. floating above C. glomerata, DO was 83% lower at 30 degrees C over seven days than in control samples with no duckweed or alga. Dissolved oxygen was lower beneath a thick mat (1 cm) of either Lemna spp. covering the surface than under a thin layer (single-frond canopy). PAM fluorimetry showed that maximum PSII efficiency (Fv/Fm) of C. glomerata in containers was reduced under a canopy of L. minor by 17% over seven days, and under L. minuscula by 22%. F'q/F'm of C. glomerata in containers exposed to 51 micromol m(-2) s(-1) PPFD decreased under a canopy of L. minor by 16% over seven days, and under L. minuscula by 19% compared to controls. When light response curves were compared, F'q/F'm was significantly reduced under canopies of L. minor at the highest temperatures tested (28 degrees C and 30 degrees C). L. minor significantly reduced relative electron transport rate (rel. ETR) of the controls by up to 71% at 30 degrees C. Relative electron transport rate did not reach light saturation point (Esat) except at 28 degrees and 30 degrees C under mats of L. minor. Whereas the highest rate of production (rel. ETRmax) and Esat increased with temperature in controls, under a canopy of Lemna, decreases were observed. It is suggested that, during periods of high summer temperature and irradiance, shading inhibits oxygenic photosynthesis in mats of C. glomerata beneath canopies of Lenma spp. This results in less oxygen being produced by the C. glomerata (oxygen produced by Lemna spp. is not released into the water), and this may further inhibit the C. glomerata by limiting oxygen-dependent electron transport and/or photorespiration. This feedback loop could lead to the eventual senescence of the C. glomerata. The combination of low oxygen, high temperature and stressed filamentous algae, particularly in slow or standing water, may help to explain sudden collapses in DO concentration, with detrimental effects on water quality downstream.     

水泥含量对高纯铝尖晶石自流浇注料性能的影响

以致密刚玉和尖晶石为主要原料,铝镁尖晶石的含量为19%,在颗粒组成(5～0 mm)不变的情况下,研究了水泥含量分别为3%、8%和13%对高纯铝尖晶石自流浇注料性能的影响.结果显示1)随着水泥含量的增加,浇注料的加水量、干燥后致密度和强度均增加,但烧后致密度和强度都下降;2)水泥含量的变化对自流浇注料热态强度的影响不明显;3)随着水泥含量的增加,自流料烧后线变化增加,但水泥含量达到8%以后变化不明显;4)对于LF精炼炉渣,不管水泥的含量多少,自流料都不被渗透,但随水泥含量增加,自流料的抗熔蚀性变差;5)对于转炉钢包渣,随着水泥含量的增加,自流料的抗渗透性增强,抗熔蚀性变差,而渗透与熔蚀量之和减少;6)对于转炉末期渣,随着水泥含量增加,浇注料的抗渗透性增强,抗熔蚀性变差;7)应用相图分析了铝尖晶石浇注料的侵蚀机理,认为渣中Fe2O3或低熔点相CF的增加是渣渗透的主要原因.     

Thermomechanical treatment and transformation characteristics of Fe-Mn austenites

The effect of thermomechanical treatment on the tensile properties of metastable manganese austenites was determined, and deformation-induced transformation characteristics were analyzed by X-ray diffraction and by data derived from stress-strain curves. An improved combination of tensile strength and ductility is obtained through a processing treatment entailing ausforming and deformation-induced transformation. The two treatments are very strongly interrelated, the first imposing some limiting factors on the latter. After small ausforming deformation, the strain-induced austenite-to-martensite transformation at room temperature is slightly stimulated, but additional increments of austenite deformation have a strong retarding effect. It is concluded that the formation of a strong martensite in a work-hardened austenite matrix is most effective in enhancing strength and ductility. Formerly Postdoctoral Fellow, Department of Engineering Materials, University of Windsor, Windsor, Ontario, Canada