σ-Phase Formation in Super Austenitic Stainless Steel During Directional Solidification and Subsequent Phase Transformations

Metallurgical and Materials Transactions A - The solidification path and the σ-phase precipitation mechanism in the S31254 (UNS designation) steel are investigated thanks to Quenching during...     

Binding of Cdc48p to a ubiquitin-related UBX domain from novel yeast proteins involved in intracellular proteolysis and sporulation

The Cdc48/p97 AAA-ATPase functions in membrane fusion and ubiquitin-dependent protein degradation. Here, we show that, in yeast, Cdc48p interacts with three novel proteins, Cuil-3p, which contain a conserved ubiquitin-related (UBX) domain. Cui2p and Cui3p are closely related, interact with each other, and are localized at the perinuclear membrane. Cdc48p binds directly the UBX domain of Cui3p in vitro. Multiple deletions of the CUI1, CUI2 and CUI3 genes confer deficiency in sporulation and degradation of model ubiquitin-protein fusions. The Cuil-3 proteins were also found to interact with Ufd3p, a WD repeat protein known to associate with Cdc48p. Together, these results indicate that the Cuil-3 proteins form complexes that are components of the ubiquitin-proteasome system.     

Patterning Nanostructured,Synthetic, Polymeric Receptors by Simultaneous Projection Photolithography,Nanomolding, and Molecular Imprinting

Microscope projection photolithography is combined with nanomolding and molecular imprinting for the fast microfabrication of molecularly imprinted polymer (MIP) arrays in the form of micrometric islands of nanofilaments. Dot diameters from 70–90 μm are easily obtained using a 10× objective and a photomask carrying the desired pattern. The dots are composed of parallel nanofilaments of a high aspect ratio, 150 nm in diameter and several micrometers in length, which are obtained through a nanomolding procedure on porous alumina. The arrays are molecularly imprinted with the small molecule fluorescein or with the protein myoglobin. The fluorescein MIP arrays are able to specifically recognize their target, as demonstrated by fluorescence microscopy. A four‐fold increase in binding capacity and imprinting factor (IF = 13) is obtained compared to non‐nanostructured porous dots. Imprinting of the nanofilament arrays with the protein myoglobin as the template is also possible and allows for a high imprinting factor of 4.3. Such nanostructured microarrays of synthetic receptors obtained by projection photolithography have great potential in biosensor and biochip development.     

Robota: Clever toy and educational tool

Therapeutic and educational applications of robots have created a demand for robots showing a number of social skills. These skills include the capacity to imitate, to learn from demonstration, to interpret gestures and to recognize speech. Robot toys are an ideal platform to investigate the potential and limitations of human–robot social interactions.

This paper presents Robota, a mini-humanoid doll-shaped robot. Robota is used in an introductory robotics class at the undergraduate level. The class offers an introduction to different tools necessary for building human–robot social interactions. Through a series of hands-on projects, students learn how to use vision and speech processing and how to design learning algorithms. The goal of each project is to create an educational and entertaining game for normal and disabled children.     

Effectiveness of Collaborative Problem Solving in Affectively Dysregulated Children With Oppositional-Defiant Disorder: Initial Findings.

Oppositional-defiant disorder (ODD) refers to a recurrent pattern of negativistic, defiant, disobedient, and hostile behavior toward authority figures. Research has shown that children with ODD and comorbid mood disorders may be at particular risk for long-term adverse outcomes, including conduct disorder. In this study, the authors examined the effectiveness of a cognitive-behavioral model of intervention--called collaborative problem solving (CPS)--in comparison with parent training (PT) in 47 affectively dysregulated children with ODD. Results indicate that CPS produced significant improvements across multiple domains of functioning at posttreatment and at 4-month follow-up. These improvements were in all instances equivalent, and in many instances superior, to the improvements produced by PT. Implications of these findings for further research on and treatment selection in children with ODD are discussed. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Restoring Dynamic Fluvial Processes in Urban Rivers: Learning from the Aire and Isar Rivers

In process-based restoration, the objective is not to create a complex river form directly; instead, interventions are intended to “prompt” the natural processes to restore such forms. The improvements in ecological conditions are actually made over time by flowing water during floods (using the stream’s energy), and by the growth of riparian vegetation (using incoming solar energy). On the Aire River in Geneva, ecological function was restored to a formerly canalized river by providing the river with an espace de liberté. A grid of channels cut into the valley bottom allowed the river to freely flood, erode its bed and banks, and deposit bars, creating complex surfaces on which riparian vegetation established to support the food web of the riverine ecosystem. The diamond-shaped bits of land left between these channels (“lozenges”) gradually erode and evolve as the river migrates, creating complex channel forms. The Isar River in Munich restoration involved adding coarse sediment load, creating erodible bed and banks in place of formerly rigid boundaries, expanding process space for river migration, erosion, and deposition, and increased human access to the river over 8 km. Since restoration, natural transport of sediment has resulted in deposition of gravel bars, whose forms evolve during floods, supporting diverse habitats. The Isar and Aire Rivers provide compelling examples of processbased restoration meeting 4 criteria for process-based restoration: space, energy, materials, and time. They demonstrate the possibilities of urban river restoration to achieve both ecological and social goals through restoration of fluvial process.     

Torque,temperature and hardening precipitation evolution in dissimilar friction stir welds between 6061-T6 and 2014-T6 aluminum alloys

Dissimilar friction stir butt welds between the 2014-T6 and the 6061-T6 Al alloys were performed with various sets of welding parameters including a lateral shift of the tool from the initial separation between the plates to be welded and by placing the alloys, either on the advancing, or on the retreating side of the weld. Torque and temperature measurements during welding as well as macrographies and hardness profiles measurements were performed after welding. It was found that the welding torque, the temperature, the metal flow and the welds’ hardness profile depend on the proportion of each alloy included in the stirred zone. Those results are attributed to the difference between the softening temperatures of both alloys. The 6061 alloy's HAZ is the weak link in all dissimilar welds. The evolution of the hardening precipitation, the hardness and the local yield strength in the 6061 alloy are therefore modeled. The model reasonably well predicts the experimentally measured hardness of both similar and dissimilar welds. It also explains the influence of the alloys placement or tool lateral shift on the welds hardness by their influence on the precipitate radius and volume fraction.     

A survey of Tactile Human–Robot Interactions

Robots come into physical contact with humans in both experimental and operational settings. Many potential factors motivate the detection of human contact, ranging from safe robot operation around humans, to robot behaviors that depend on human guidance. This article presents a review of current research within the field of Tactile Human–Robot Interactions (Tactile HRI), where physical contact from a human is detected by a robot during the execution or development of robot behaviors. Approaches are presented from two viewpoints: the types of physical interactions that occur between the human and robot, and the types of sensors used to detect these interactions. We contribute a structure for the categorization of Tactile HRI research within each viewpoint. Tactile sensing techniques are grouped into three categories, according to what covers the sensors: (i) a hard shell, (ii) a flexible substrate or (iii) no covering. Three categories of physical HRI likewise are identified, consisting of contact that (i) interferes with robot behavior execution, (ii) contributes to behavior execution and (iii) contributes to behavior development. We populate each category with the current literature, and furthermore identify the state-of-the-art within categories and promising areas for future research.     

Therapy for youths with anxiety disorders: A second randomized clincal trial.

Ninety-four children (aged 9-13 years) with anxiety disorders were randomly assigned to cognitive behavioral treatment or waiting-list control. Outcomes were evaluated using diagnostic status, child self-reports, parent and teacher reports, cognitive assessment and behavioral observation; maintenance was examined using l-year follow-up data. Analyses of dependent measures indicated significant improvements over time, with the majority indicating greater gains for those receiving treatment. Treatment gains returned cases to within nondeviant limits (i.e., normative comparisons) and were maintained at l-year follow-up. Client age and comorbid status did not moderate outcomes. A preliminary examination of treatment segments suggested that the enactive exposure (when it follows cognitive-educational training) was an active force in beneficial change. Discussion includes suggestions for future research. (PsycINFO Database Record (c) 2010 APA, all rights reserved)