Synthesis and properties of novel fully conjugated polymers containing bithiazole rings

Two novel fully conjugated polymers containing bithiazole rings (PDDBTz and PDABTz) were first synthesized by polycondensation of 2,7-dimethyl-2,4,6-octatriene-1,8-dial with 2,2′-bis(diethylphosphinatyl methyl)-4,4′-bithizole or 2,2′-diamino-4,4′-bithiazole (DABT). The structure of the polymers was determined by IR, ¹H NMR and elemental analysis. PDDBTz is soluble in trifluoroacetic acid and DMSO, whereas PDABTz is soluble in common solvent such as THF, DMSO, DMF. Bithiazole rings were introduced to provide bidentate N-donor sites for binding metal ions. Their lanthanide metal complexes were prepared. The magnetic behavior of these polymeric complexes was measured as a function of magnetic field strength (0-60 kOe) at 4 K and as a function of temperature (4-300 K) at magnetic field strength of 30 kOe. The results show that they all exhibit features of soft ferromagnet.     

炭阳极气泡振动信号的谱分析与阳极效应预报

本文提出一种新的阳极效应预报方法，该方法根据故障检测原理，采用谱估计和时频分析等现代信号理论，可对阳极效应有效地进行预报，不仅可以提高铝的产量和质量．而且对节能和保证整个电解系列平稳安全生产，具有很重要的意义。     

动力调谐陀螺仪动力吸振器的研究

建立了动调陀螺轴向振动力学模型，并根据仪表的具体结构，设计了两种不同结构形式的吸振器以用于动调陀螺的抑制。理论和实验数据表明，在动调陀螺轴系上附加有阻尼的动力吸振器，可以大幅度地降低仪表谐振时的振动放大量级，改善仪表的振动特性，提高其抗随机振动能力。     

微机在电热设备电磁兼容上的应用

交、直流电弧炉和晶闸管整流、变频、调压、调功装置产生的高次谐波，电弧炉和工频感应装置导致的负序电流和负序电压以及电弧炉产生的电压波动和闪变已严重影响到供电电网的正常运行。本文主要叙述电热设备电磁兼容（谐波、负序和闪变等）的有关数学模式以及作者用自行开发的电磁兼容软件在国内实际应用事例。     

工业铝电解质分子比的演变与现状

在铝电解工业初期，采用分子比３．０左右的电解质，电解温度高达１０００℃；经五十余年后逐渐降低到２．６左右；现在先进的大型电解槽已经使用了分子比为２．１～２．２的电解质，电解温度降低到９５０℃左右。采用新型电解槽与低温度电解（８５０～９００℃）也许可使电耗率减少到１２０００ｋＷ·ｈ／ｔＡｌ。这时候，铝电解质的分子比和电解法发明人霍尔原来的专利方案接近了，达到了一个新的水平     

某单位合理低价投标而未中标原因剖析

通过某单位合理低价投标而未能中标的具体案例分析,剖析因评标方法不同,合理低价投标不是能否中标的关键,而领会招标单位的招标文件精髓,完全响应招标单位的要求,紧贴评标办法投标,才是投标单位能否中标的关键。     

Assemblies of Peptide‐Cytotoxin Conjugates for Tumor‐Homing Chemotherapy

Peptide‐drug conjugates are prodrugs that have the advantages of precise molecular structure and the direct exploitation of tumor‐homing, penetration or the cellular uptake abilities of the peptides such as the neuropilin‐1 receptor targeting peptide. The prodrugs generally have fast blood clearance due to their low molecular weights and thus are made to self‐assemble into nanostructures, preferably nanosized micelles and vesicles for intravenous administration, to slow their renal clearance. However, most peptidyl prodrugs usually form precipitates, irregular nanofibers or gels that are unsuitable for intravenous injection. Herein, a arginine‐glycine‐aspartic acid‐lysine (RGDK) peptide and cytotoxin 7‐ethyl‐10‐hydroxycamptothecin (SN38) are used to synthesize the tumor‐homing prodrugs (SN38‐Peps) and explore their structure–micelle formation relationships. A small library of SN38‐Peps is obtained using different structures of peptides, linkers, and drug conjugation sites, and the factors affecting the assembly of SN38‐Peps as well as the stability of formed micelles are investigated. An optimized SN38‐Pep, (MOM)SN38(20)‐CRGDK, is finally obtained which forms stable micelles with a hydrodynamic diameter around 110 nm and a fixed drug loading content as high as 35%. The micelles show a prolonged blood circulation, significantly enhanced tumor accumulation, and therefore improved anticancer activity as compared to the non‐targeting prodrug and a clinically used anticancer drug.     

用GYS-S系列小样染布机实现一次染色成功

介绍了一次染色成功的成本效益情况,采用GYS-S系列小样染布机模拟车间染色机现场染色情况,指出了相应的工艺流程、方法、曲线和参数,分析了提高一次染色成功在生产和管理上的误区,并阐述了相应的措施,结果得出,采用GYS-S系列小样染布机模拟现场生产条件染色,一次染色成功率可提高到90%以上。     

大型中间下料预焙槽与侧部下料自焙槽工艺参数的比较

通过低温铝电解的生产实践 ,分析了大型预焙槽在结构上、操作上和故障处理等方面与小自焙槽的区别。并从理论上分析了主要技术参数的选择依据 ,供铝电解工程技术人员参考     

NaF-AlF_3熔体中铝在钨电极上的电化学沉积

用循环伏安法与计时电位法研究了950℃下碱性冰晶石熔体(分子比6.5)中铝在钨电极上的电化学沉积过程。结果表明,由于铝与钨形成金属间化合物,导致铝沉积过程的复杂化,因而不能简单地把钨作为研究冰晶石熔体中铝析出与溶解的工作电极。