MHD mixed convection of a Cu–water nanofluid flow through a channel with an open trapezoidal cavity and an elliptical obstacle

In the current work, numerical simulations are achieved to study the properties and the characteristics of fluid flow and heat transfer of (Cu–water) nanofluid under the magnetohydrodynamic effects in a horizontal rectangular canal with an open trapezoidal enclosure and an elliptical obstacle. The cavity lower wall is grooved and represents the heat source while the obstacle represents a stationary cold wall. On the other hand, the rest of the walls are considered adiabatic. The governing equations for this investigation are formulated, nondimensionalized, and then solved by Galerkin finite element approach. The numerical findings were examined across a wide range of Richardson number (0.1 ≤ Ri ≤ 10), Reynolds number (1 ≤ Re ≤ 125), Hartmann number (0 ≤ Ha ≤ 100), and volume fraction of nanofluid (0 ≤ φ ≤ 0.05). The current study's findings demonstrate that the flow strength increases inversely as the Reynolds number rises, which pushes the isotherms down to the lower part of the trapezoidal cavity. The Nu_avg rises as the Ri rise, the maximum Nu_avg = 10.345 at Ri = 10, Re = 50, ϕ = 0.05, and Ha = 0; however, it reduces with increasing Hartmann number. Also, it increase by increasing ϕ, at Ri = 10, the Nu_avg increased by 8.44% when the volume fraction of nanofluid increased from (ϕ = 0–0.05).     

Method for calculating horizontal drain induced non-linear and large strain degree of consolidation

Consolidating dredged clay slurries using a combination of vacuum pressure and prefabricated horizontal drains (PHDs) is widely used in practice. This is a large strain problem, but there is no existing large strain theory for PHD induced consolidation. A method with explicit equations has been proposed to consider both mechanical and geometrical non-linearities in analyzing PHD induced consolidation. The method considers stepwise variation of properties using imaginary time concept. An imaginary time is determined by the condition of continuity of degree of consolidation before and after changing the properties. Then the method was applied to analyze a large scale model test of vacuum consolidation with PHD. Two analyses were conducted. One considered both the mechanical and geometrical non-linearity (large strain), and another only considered mechanical non-linearity (small strain). The results of large strain analysis agree with the measured settlement curve and excess pore pressures well. While the small strain analysis under-estimated the rate of consolidation significantly. The results from this study indicate that for analyzing PHD induced consolidation of clay slurries considering the effect of large strain is important, and the proposed method can be a useful design tool.     

Acquisition and Spread of Antimicrobial Resistance: A tet(X) Case Study

Understanding the mechanisms leading to the rise and dissemination of antimicrobial resistance (AMR) is crucially important for the preservation of power of antimicrobials and controlling infectious diseases. Measures to monitor and detect AMR, however, have been significantly delayed and introduced much later after the beginning of industrial production and consumption of antimicrobials. However, monitoring and detection of AMR is largely focused on bacterial pathogens, thus missing multiple key events which take place before the emergence and spread of AMR among the pathogens. In this regard, careful analysis of AMR development towards recently introduced antimicrobials may serve as a valuable example for the better understanding of mechanisms driving AMR evolution. Here, the example of evolution of tet(X), which confers resistance to the next-generation tetracyclines, is summarised and discussed. Initial mechanisms of resistance to these antimicrobials among pathogens were mostly via chromosomal mutations leading to the overexpression of efflux pumps. High-level resistance was achieved only after the acquisition of flavin-dependent monooxygenase-encoding genes from the environmental microbiota. These genes confer resistance to all tetracyclines, including the next-generation tetracyclines, and thus were termed tet(X). ISCR2 and IS26, as well as a variety of conjugative and mobilizable plasmids of different incompatibility groups, played an essential role in the acquisition of tet(X) genes from natural reservoirs and in further dissemination among bacterial commensals and pathogens. This process, which took place within the last decade, demonstrates how rapidly AMR evolution may progress, taking away some drugs of last resort from our arsenal.     

纵轴式掘进机截割头载荷影响因素的仿真分析

针对现有掘进机截割头载荷特性研究方法采用单一影响因素不能全面反映截割头载荷及其波动变化规律的问题,通过分析截割头瞬时载荷,确定了纵轴式掘进机在水平截割工况下截割头载荷的主要影响因素有截割岩石特性、截割头掏槽深度、截割头吃刀深度、截割头转速和截割臂摆速。针对某纵轴式掘进机水平截割工况,采用Matlab对影响截割头载荷的多种因素进行仿真分析,得到了各向载荷及其波动随各因素的变化规律:截割头载荷随着岩壁普氏系数的增大而增加,其中横向阻力增加尤为明显,横向阻力波动程度高于其他方向载荷,且随着岩壁普氏系数的增大呈减小趋势;随着截割头掏槽深度的增加,截割头各向载荷近似呈线性增加,其中升力增加幅度最大,各向载荷波动则随着截割头掏槽深度的增大而减小;随着吃刀深度的增加,截割头载荷总体呈增大趋势,载荷波动程度则随之减小;在截割头转速一定的情况下,截割头载荷均随着截割臂摆速的增加而增大,在同一摆速下,截割头载荷随着截割头转速的减小而增大,横向阻力波动明显高于升力和推进阻力波动,横向阻力和推进阻力波动按截割头载荷规律变化,升力波动则与之相反。截割头载荷波动变化规律与截割头载荷变化规律不尽一致,有时甚至相互冲突。因此,掘进机作业过程中应合理选择截割头掏槽深度、吃刀深度等操作参数和截割头转速、截割臂摆速等运动参数,使各参数相互匹配,以减小掘进机振动,延长使用寿命。     

水电站大型竖井施工安全风险控制措施研究

竖井是大型水电工程中广泛采用的重要建筑物,但竖井的传统施工方法存在施工程序复杂、人工劳动强度大、施工效率不高等特点,同时还存在较大的安全风险。通过对杨房沟水电站大型竖井施工过程的研究,总结出精细化控制爆破、小溜渣井施工方式,同时也设计了一套用于运输的综合提升系统。采用上述创新方法不仅减少了繁琐的施工程序,降低了安全施工风险,而且大量采用机械化手段进一步提高了施工效率,确保了该工程竖井施工的安全风险可控。相关措施可为类似工程的竖井施工提供较好的借鉴作用。     

张庄铁矿高阶段矿房切割天井施工工艺试验

张庄铁矿设计采矿方法为大直径深孔阶段空场嗣后充填法。为了最大化发挥采矿设备性能，降低采切工程量，提高回采效率，通过实施一系列技术攻关，实现了将采矿阶段高度由原来的60 m提高到90 m。而作为最初爆破回采的自由面及爆破补偿空间，切割天井施工工艺为影响高阶段矿房爆破回采效果的关键因素，施工质量的优劣，直接影响矿房爆破回采生产作业能否顺利进行，而二次处理在增加施工成本的同时将带来安全隐患。张庄铁矿在面临可参考的成熟经验较少的情况下，结合现场可用的作业条件采取了对比试验的方法，在安全、技术及经济多方面综合分析比较下，确定了最终方案，为张庄铁矿安全稳定生产奠定了基础，同时研究成果可为大型地下矿山生产实践提供一定的参考。     

压裂水平井产能预测方法研究进展

水平井压裂技术在低渗透及非常规储层中得到了广泛应用,压裂后水平井的产能预测关系到油田开发方案的制定,因此,国内外学者对压后渗流模型的建立和求解方法做出了不懈的努力。本文详细回顾了国内外学者所建压裂水平井产能预测模型及求解方法,指出了不同模型和求解方法的优缺点,并展望了压裂水平井产能模型的发展方向。     

裸眼井中扩张式封隔器力学行为研究

封隔器在石油天然气开采中起着非常重要的作用,而扩张式封隔器在裸眼井中广泛应用。本文采用有限元软件建立了裸眼封隔器与地层的模型,对胶筒在坐封过程中与井壁接触应力的变化进行了研究,并研究了在不同摩擦系数下接触压力的变化,结果表明,建立粗糙井壁面能够更加符合实际情况,胶筒肩部为应力集中的区域,地层与胶筒的接触应力会随着摩擦系数的增加而减小。研究结果为裸眼扩张式封隔器的设计和改进提供了理论依据。     

抽油井不压井作业装置及抽油泵底阀设计

江苏油田的部分油井存在油管短路、地层高压低渗、漏失严重等问题,这些问题造成压井作业困难,并且压井作业过程中的井控与环境污染风险较大。为了进行不压井检泵作业,同时缩短检泵之后的产量恢复周期,进行了不压井作业技术研究,并研制了不压井作业装置。为解决起下抽油杆过程中的防喷问题,改进了抽油泵底阀结构,该结构可实现起下抽油杆过程中油管不带压、无溢流,并保障起下油管过程中的井控安全。该技术在江苏油田现场应用9井次,效果良好。     

气藏采收率影响因素研究与启示——以靖边气田A井区为例

以鄂尔多斯盆地靖边气田A井区为例，采用单因素相关分析和数值模拟方法，对比研究了井网控制程度、储层物性及地层废弃压力对气藏采收率影响及其主次关系。结果表明，井网控制程度是影响采收率的首要因素，井网控制程度每增加10%，采收率提高8.5%；渗透率是影响采收率的重要因素，渗透率每增加10%，采收率平均增加6%；废弃压力对采收率亦有较大影响，废弃压力每降低10%，采收率可提高1.6%。三者对采收率影响综合排序为：井网控制程度>储层物性>废弃压力。分析认为，渗透率是储层固有属性，很难从根本改变；而废弃压力受井口外输压力和增压开采成本制约，降低幅度有限。因此，优化井网及增加井网控制程度是提高气藏采收率的有效途径。研究成果具有实践意义，可为改进气田开发方式和提高气藏采收率提供参考。