Electrochemical Quantification of Neurotransmitters in Single Live Cell Vesicles Shows Exocytosis is Predominantly Partial

Exocytosis plays an essential role in the communication between cells in the nervous system. Understanding the regulation of neurotransmitter release during exocytosis and the amount of neurotransmitter content that is stored in vesicles is of importance, as it provides fundamental insights to understand how the brain works and how neurons elicit a certain behavior. In this minireview, we summarize recent progress in amperometric measurements for monitoring exocytosis in single cells and electrochemical cytometry measurements of vesicular neurotransmitter content in individual vesicles. Important steps have increased our understanding of the different mechanisms of exocytosis. Increasing evidence is firmly establishing that partial release is the primary mechanism of release in multiple cell types.     

负径向电场对带电粒子俘获率影响的数值模拟

本文采用数值方法求解Grad-Shafranov方程反演EAST典型长脉冲放电实验(炮号33068)的平衡位形和磁场分布，进而结合粒子在托卡马克电磁场中的运动方程，模拟氘离子在负径向电场存在时的运动轨迹，并统计不同负径向电场下的氘离子俘获率。结果表明：随负径向电场的增大，氘离子轨迹由扩张通行轨迹向外翻香蕉轨迹再向内翻香蕉轨迹，最后向压缩通行轨迹演变；氘离子俘获率随负径向电场的增大而减小，氘离子初始速度越小，其变化越大。     

Self-consistent kinetic theory with nonlinear wave-particle resonances

We have developed, based on the oscillating-center transformation, a general theoretical approach for self-consistent plasma dynamics including, explicitly, effects of nonlinear(higherorder) wave-particle resonances. A specific example is then given for low-frequency responses of trapped particles in axisymmetric tokamaks. Possible applications to transport as well as nonlinear wave growth/damping are also briefly discussed.     

湖州南方中转仓储及输送工程建设特点

介绍了湖州南方物流有限公司中转仓储及输送工程项目的建设背景、建设条件,以及线路规划、主要技术方案,该项目是国内采用长距离越野曲线带式输送机系统运输熟料距离最长的绿色环保工程。项目以电力驱动运输替代汽车运输,日输送量达4.5~5万吨。采用密闭廊道输送,粉尘排放量低,噪声<50dB,日均减少汽车运输3000辆次,年节约燃油2000余吨,减少了尾气排放,缓解了沿线的交通拥堵,实现了良好的经济效益和社会效益。     

闭口闪点测定方法的对比分析

对我国常用的闭口闪点测定方法宾斯基-马丁闭口杯法、阿贝尔闭口杯法和泰格闭口杯法的测定原理进行对比分析，并采用这3种方法分别对2种有证标准样品、4种有机试剂样品和7种喷气燃料样品的闭口闪点进行测定。结果表明：这3种方法在适用范围、仪器结构、升温速率和点火操作要求等方面都有一定差异，导致采用这3种方法测定同一样品的闭口闪点结果略有差异，闪点测定结果之间的最大差值与样品闪点的高低呈正相关；与阿贝尔闭口杯法相比，宾斯基-马丁闭口杯法测得的闪点结果较高，对于3号喷气燃料，二者之差为0～1.0 ℃，阿贝尔闭口杯法更适合3号喷气燃料闭口闪点的测定；对于纯有机试剂样品，阿贝尔闭口杯法和宾斯基-马丁闭口杯法测得的闪点结果呈现较好的线性关系。     

Trajectory-Shaping Guidance with final speed and load factor constraints

This paper describes the design of a guidance law used for guiding a hypersonic gliding vehicle against a ground target from a near-vertical orientation with a specified final speed and a near-zero final load factor. The guidance law consists of two terms: one is Trajectory-Shaping Guidance (TSG) used for steering the vehicle to the target from the specified orientation; the other is Final-Speed-Control Scheme (FSCS) used for controlling the vehicle to perform lateral maneuver to adjust the final speed. Further, the generalized closed form solutions of TSG are obtained from a more general linearized engagement model, where the speed of the vehicle can be an arbitrary positive function of time. By analyzing these solutions, the stability domain of the guidance coefficients is obtained such that the final load factor is zero. This domain is not affected by the change rate of the speed. Thus, according to this analysis, the proposed guidance law can achieve a near zero final load factor by properly selecting the guidance coefficients in the stability domain.     

The influence of inner material with different average thermal conductivity on the performance of whole insulation system for liquid hydrogen on orbit storage

At present, several composite insulation systems were proposed that can be used for passive insulation systems, including foam-variable density multilayer insulation (VDMLI), aerogel-VDMLI and hollow glass microspheres (HGMs)-VDMLI. The passive insulation systems with different inner material (IM) showed different performances. However, the relationship between the average thermal conductivity of IM and the insulation performance of the whole system has rarely been investigated. It is of great significance for efficient configuration and matching of the passive insulation system. In this paper, a series of average thermal conductivity of IM were assumed to predict the insulation performance of the whole system at 20 K–300 K and high vacuum. In order to further illustrate the relationship between IM and MLI/VDMLI, the foam was replaced by the HGMs as 5 mm a unit forming a series of HGMs-foam-MLI/VDMLI insulation systems. The performance of the systems was investigated. After the foam was completely replaced by the HGMs, the performance of MLI and VDMLI systems was improved 33% and 13%, respectively. Moreover, each mode of heat transfer including solid conduction, radiation, and gas conduction for foam-MLI/VDMLI and HGMs-MLI/VDMLI insulation systems were calculated and analyzed.     

Recent progress of green sorbents-based technologies for low concentration CO2 capture

The increased concentration of CO₂ due to continuous breathing and no discharge of human beings in the manned closed space, like spacecraft and submarines, can be a threat to health and safety. Effective removal of low concentration CO₂ from the manned closed space is essential to meet the requirements of long-term space or deep-sea exploration, which is an international frontier and trend. Ionic liquids (ILs), as a widespread and green solvent, already showed its excellent performance on CO₂ capture and absorption, indicating its potential application in low concentration CO₂ capture. In this review, we first summarized the current methods and strategies for direct capture from low concentration CO₂ in both the atmosphere and manned closed spaces. Then, the multi-scale simulation methods of CO₂ capture by ionic liquids are described in detail, including screening ionic liquids by COSMO-RS methods, capture mechanism by density functional theory and molecular dynamics simulation, and absorption process by computational fluid dynamics simulation. Lastly, some typical IL-based green technologies for low concentration CO₂ capture, such as functionalized ILs, co-solvent systems with ILs, and supported materials based on ILs, are introduced, and analyzed the subtle possibility in manned closed spaces. Finally, we look forward to the technology and development of low concentration CO₂ capture, which can meet the needs of human survival in closed space and proposed that supported materials with ionic liquids have great advantages and infinite possibilities in the vital area.     

Radiation damage behavior of carbon/carbon composite in Low Earth Orbit environment

To understand the degradation behavior of Carbon/Carbon(C/C) composite in LEO radiation environment, groups of 2D-C/C composites samples were exposed to ground-based Low Earth Orbit(LEO) simulating facilities. The LEO radiating environment covers part of Van Allen inner belt, which contains atomic oxygen(AO) and high-energy proton radiating regions. These two kinds of radiating sources were arranged for simulating the real LEO radiating conditions regarding to the first orbit movement speed of serving space shuttles. Changes of micro-structure, mass loss, surface roughness, chemical construction and thermal physical properties after environmental assessment were analyzed and compared to understand the damage behavior of LEO radiation on C/C composite. It was found that AO is the main factor of mass loss in LEO radiating particles. The charged high-energy protons have an aggravating damage ability with energetic AO, damage situations of degree in orbit down process is more serious than in orbit rising process. The LEO radiation damage mechanisms of C/C composite are revealed and expounded either.     

闭式外腔循环太阳能墙集热效果实验研究

文章设计了闭式外腔循环太阳能墙系统,从理论和实验两方面研究太阳能墙传热传质规律。以大连市冬季为研究背景,基于对实验测温点不同时刻的持续监测,从逐时曲线中分析了不同环境下闭式外腔循环系统内部温度以及室内获得热量后室温的变化情况。结果表明,太阳能墙集热效率与太阳辐射强度密切相关,在晴朗天气下,白天部分时段单一太阳能墙就能满足采暖要求,不满足采暖要求时可以选择空气源热泵辅助采暖。