Application of artificial neural network method to predict the breakage properties of PGE bearing chromite ore

In the present investigation, systematic grinding experiments were conducted in a laboratory ball mill to determine the breakage properties of low-grade PGE bearing chromite ore. The population balance modeling technique was used to study the breakage parameters such as primary breakage distribution (B_{i, j}) and the specific rates of breakage (S_i). The breakage and selection function values were determined for six feed sizes. The results stated that the breakage follows the first-order grinding kinetics for all the feed sizes. It was observed that the coarser feed sizes exhibit higher selection function values than the finer feed size. Further, an artificial neural network was used to predict breakage characteristics of low-grade PGE bearing chromite ore. The predicted results obtained from the neural network modeling were close to the experimental results with a correlation of determination R² = 0.99 for both product size and selection function.     

Cognitive and affective processes for learning science in immersive virtual reality

As immersive virtual reality (IVR) systems proliferate in classrooms, it is important to understand how they affect learning outcomes and the underlying affective and cognitive processes that may cause these outcomes. Proponents argue that IVR could improve learning by increasing positive affective and cognitive processing, thereby supporting improved performance on tests of learning outcome, whereas opponents of IVR contend that it could hurt learning by increasing distraction, thereby disrupting cognitive learning processes and leading to poorer learning outcomes. In a media comparison study, students viewed a biology lesson either as an interactive animated journey in IVR or as a slideshow on a desktop monitor. Those who viewed the IVR lesson performed significantly worse on transfer tests, reported higher emotional arousal, reported more extraneous cognitive load and showed less engagement based on EEG measures than those who viewed the slideshow lesson, with or without practice questions added to the lessons. Mediational analyses showed that the lower retention scores for the IVR lesson were related to an increase in self-reported extraneous cognitive load and emotional arousal. These results support the notion that immersive environments create high affective and cognitive distraction, which leads to poorer learning outcomes than desktop environments.     

论携号转网行为的私法规制

以电信用户入网协议为切入点,电信用户的携号转网行为应受到《合同法》《消费者权益保护法》等私法规范的保护与限制。该行为引起的格式条款解释、合同终止、违约责任、损失赔偿等问题,不能仅靠《电信条例》等公法规范来调整。应当积极引导广大消费者用户以私法领域相关规定为依据,转变争议解决思维,拓宽纠纷处理途径,合理选择维权手段,以保护自身合法民事权益,与行业监管部门共同推动电信行业有序发展。     

Natural food mastication capability in preschool children according to their oral condition: A preliminary study

This study investigated, for the first time, the masticatory capability of preschool children using natural foods, and the impact of an early oral health alteration (early childhood caries: ECC) on the granulometry of ready-to-swallow food boluses. Thirteen children with ECC were compared to 13 preschool children with a healthy oral condition. Oral health criteria and NOT-S scores (Nordic Orofacial dysfunction Test-Screening) were recorded. For each child, number of masticatory cycles (Nc), chewing time (Ti), and frequency (Fq = Nc/Ti) were recorded during mastication of raw carrot (CAR), cheese (CHS) and breakfast cereals (CER) samples. Food boluses were collected by stopping children at their food-dependent individual swallowing threshold (Nc), and the median food bolus particle size value (D50) was calculated. Correlations were sought between oral health and masticatory criteria. In the ECC group, mean Fq values were significantly decreased for all three foods (p ≤ .001) and mean D50 values were significantly increased (p ≤ .001) compared to the control group (i.e., D50 CAR = 4,384 μm ± 929 vs. 2,960 μm ± 627). These alterations were related to the extent of ECC. The NOT-S mean global score was significantly increased in children with ECC (2.62 ± 1.37 vs. 1 ± 0.91 in the control group, p ≤ .01), due to “Mastication and swallowing” domain impairment. This study gives granulometric normative values for three foods in preschool children and shows the impact of ECC on D50 values. The progression of children's masticatory capability after dental treatment, and the impact of such modifications of sensory input on future eating habits should be explored.     

Applied data science in patient-centric healthcare: Adaptive analytic systems for empowering physicians and patients

We define the emerging research field of applied data science as the knowledge discovery process in which analytic systems are designed and evaluated to improve the daily practices of domain experts. We investigate adaptive analytic systems as a novel research perspective of the three intertwining aspects within the knowledge discovery process in healthcare: domain and data understanding for physician- and patient-centric healthcare, data preprocessing and modelling using natural language processing and (big) data analytic techniques, and model evaluation and knowledge deployment through information infrastructures. We align these knowledge discovery aspects with the design science research steps of problem investigation, treatment design, and treatment validation, respectively. We note that the adaptive component in healthcare system prototypes may translate to data-driven personalisation aspects including personalised medicine. We explore how applied data science for patient-centric healthcare can thus empower physicians and patients to more effectively and efficiently improve healthcare. We propose meta-algorithmic modelling as a solution-oriented design science research framework in alignment with the knowledge discovery process to address the three key dilemmas in the emerging “post-algorithmic era” of data science: depth versus breadth, selection versus configuration, and accuracy versus transparency.     

公路治超必须从动态称重抓起

公路治超事业与动态称重事业是一对相互依存的共同体,治超离不开动态称重,动态称重也离不开治超事业。在"四个一流"公路治超体系建设的同时,与公路治超同呼吸共命运的动态称重技术也取得了很大发展,已经完成了由轴载荷计重模式向整车称重模式的转化,新技术已经具备高准确度、高稳定性、高通行率等特征,能够适应公路现场应用,计量结果完全不受车辆不规则驾驶的影响,精准可靠。公路治超事业需要准确的称重技术,动态称重技术需要公路治超的舞台,"四个一流"的公路治超信息化体系建设更离不开一流的动态称重技术。     

儿童用品TBT通报数据可视化预警研究

探索采用数据可视化技术分析儿童用品TBT通报数据,以可视化图形图像呈现通报热点并揭示趋势信息,提出对策与建议,助力为儿童用品产业升级、TBT预警数据分析和信息传播工作提供新思路,提高中小企业的国外市场准入机会。     

依托泊苷联合卡铂用于复发性髓母细胞瘤患儿的疗效与安全性

目的:探讨依托泊苷联合卡铂用于复发性髓母细胞瘤患儿的疗效与安全性。方法:选取浙江大学医学院附属儿童医院在2011年1月至2014年6月收治的72例复发性髓母细胞瘤患儿（3～15岁），随机分为CE组和对照组，每组36例，CE组采用依托泊苷＋卡铂给药方式化疗；对照组采用经典伊立替康＋替莫唑胺＋长春新碱方案化疗。比较两组患儿临床疗效、卡诺夫斯基健康状况量表（KPS）评分、儿科生活质量测定量表4.0（PedsQLTM4.0）评分、总生存期（OS）、无事件生存（EFS），记录患儿治疗期间药物不良反应的发生情况。结果:治疗后CE组和对照组完全缓解率（CR）分别为41.67%（15/36）和27.78%（10/36），总缓解率（OR）分别为94.44%（34/36）和77.78%（28/36），差异有统计学意义（P<0.05）。两组患儿治疗前KPS评分及PedsQLTM4.0评分无统计学差异（P＞0.05），治疗后CE组和对照组的KPS评分分别为（80±8）和（75±10）分，PedsQLTM4.0评分分别为（89±11）和（84±11）分，差异均有统计学意义（均P<0.05）。截至末次随访时间，CE组有3例失访，对照组有2例失访。截至末次随访时间，CE组和对照组总生存率分别为78.8%（26/33）和55.9%（19/34），差异有统计学意义（P<0.05），无事件生存率分别为72.7%（24/33）和52.9%（18/34），差异无统计学意义（P＞0.05）。CE组化疗期间共出现10例3级以上不良反应，发生率为27.78%（10/36），对照组化疗期间共出现9例3级以上不良反应，发生率为25.00%（9/36），差异无统计学意义（P＞0.05）。结论:依托泊苷联合卡铂方案能够明显提高患儿临床缓解率，延长患儿总生存率，同时不增加化疗不良反应，但对无事件生存率的影响并不明显。