适用于无线体域网的动态口令认证协议

无线体域网中传输的是与生命高度相关的敏感数据，身份认证是信息安全保护的第一道防线。现有的基于人体生物信息的身份认证方案存在信息难提取、偶然性大和误差性大的问题，基于传统密码学的认证方案需较大计算资源和能量消耗，并不适用于无线体域网环境。为此，在动态口令和非对称加密机制基础上，提出一种适用于无线体域网的动态口令双向认证轻量协议，并对其进行形式化分析。通过理论证明、SVO逻辑推理及SPIN模型检测得出：该协议满足双向认证，且能够抵御重放攻击、伪装攻击、拒绝服务器攻击和口令离线攻击，具有较高安全性。     

废旧橡胶回收再利用方法概述

概述了国内外废橡胶回收利用情况。介绍了原型利用、废旧轮胎翻新、生产再生橡胶、生产硫化胶粉、热分解和热能利用6种对废橡胶的回收再利用方法，指出开发绿色回收工艺，高效、合理利用废旧橡胶是符合可持续发展战略的重要举措。     

基于用户调研的冰雪运动头盔性能需求分析

通过问卷调查的方法,围绕冰雪运动头盔品牌、性能、价格、附加功能等因素在采购及使用中的重要程度,对具有较丰富冰雪运动经验的受访者进行了调查研究.研究过程收到有效调研结果104份,受访者广泛的来自不同性别、年龄段,参加过一定级别的专业冰雪运动竞赛.调研结果显示:当前冰雪运动头盔市场主要被欧美国家品牌占领;安全性、舒适性及美观是开发冰雪运动头盔最需考虑的因素;兼容搜救、运动拍摄、实时对讲等提升安全性及娱乐性的功能,向智能化发展是冰雪运动头盔的发展趋势.     

同向啮合双螺杆挤出机制备高性能环保再生橡胶及其性能研究

用同向啮合双螺杆挤出机对废旧轮胎全胎胶粉进行剪切脱硫,制备高性能环保再生橡胶,考察挤出工艺、补强树脂和软化剂的种类与用量对再生橡胶性能的影响。结果表明:挤出最佳工艺参数为机筒第1—13区温度为140/140/70/190/130/120/110/110/100/110/100/90/80℃,螺杆转速为140 r·min~(-1);与添加植物系软化剂的再生橡胶相比,添加矿物系软化剂固体无味油的再生橡胶物理性能更好;添加4份古马隆树脂作为补强剂,10份固体无味油作为软化剂,制备的再生橡胶物理性能最好。     

相分离法在核电厂一回路溶解氢测定中的应用

文章建立了用相分离测定反应堆冷却水中溶解氢的方法,该方法以氮气作为载气,通过水样减压、氮气鼓泡,将反应堆冷却水中溶解氢转化到气相中,再用气相色谱测定,间接得出反应堆冷却水中溶解氢的浓度,适用于反应堆水样的分析。     

The Potential Toxic Side Effects of Flavonoids

Flavonoids are a class of phytochemical molecules abundant in many plants, fruits, vegetables, and leaves. Flavonoids possess a series of significant biological activities, including anticancer, antioxidant, antiviral, and antiinflammatory properties. They become an important source of dietary supplements and natural health products. Though many studies confirmed the safety of flavonoids, the potential toxicity of flavonoids is still a remarkable field of research to be explored. The enthusiasm for flavonoids expressed by the public has sometimes overlooked their toxicity and also consumed the flavonoids exceeding the body requirements. The current review focused on the potential toxicity of flavonoids to make the public consume flavonoids with caution. This review summarizes the current toxicity which has been reported in vivo and in vitro experiments. The toxicity involves carcinogenicity and mutation, liver and kidney toxicity, and the influence on the thyroid and reproductive function and intestinal flora disorders. The mechanism of toxicity is fully complicated, and current evidence indicates that natural flavonoid glycosides act on different targets with different doses in vivo and in vitro experiments. Though most kinds of flavonoids are considered safe, flavonoids proposed as food supplements need to be assessed their tolerable upper intake level as there have been reports of toxic flavonoids.     

An integrated bioinformatics analysis and experimental study identified key biomarkers CD300A or CXCL1, pathways and immune infiltration in diabetic nephropathy mice

Diabetic nephropathy (DN) is a common microvascular complication that easily leads to end-stage renal disease. It is important to explore the key biomarkers and molecular mechanisms relevant to diabetic nephropathy (DN). We used highthroughput RNA sequencing to obtain the genes related to DN glomerular tissues and healthy glomerular tissues of mice. Then we used LIMMA to analyze differentially expressed genes (DEGs) between DN and non-diabetic glomerular samples. And we performed KEGG, gene ontology functional (GO) enrichment, and gene set enrichment analysis to reveal the signaling pathway of the disease. The CIBERSORT algorithm based on support vector machine was used to determine the immune infiltration score. Random forest algorithm and Cytoscape obtained hub genes. Finally, we applied co-staining, immunohistochemical staining, RT-qPCR and western blotting to validate the protein and mRNA expression of both hub genes. We obtained 913 DEGs mainly related to inflammatory factors and immunity. GSEA results showed that differential genes were mainly enriched in IL-17 signaling pathway, lipid and atherosclerosis, rheumatoid arthritis, TNF signaling pathway, neutrophil extracellular trap formation, Staphylococcus aureus infection and other pathways. The intersection of the random forest algorithm and Cytoscape revealed both hub genes of CD300A and CXCL1. Experiments have shown that the both key genes of CD300A and CXCL1 shown increased expression in glomerular podocytes, and are related to the inflammation of diabetic nephropathy. And immunohistochemical staining and RT-qPCR further confirmed that the protein and mRNA expression level of CD300A or CXCL1 in glomeruli tissue in DN mice were increased. The expression levels of CD300A and CXCL1 increased significantly under HG (high glucose) stimulation, further confirming that diabetes can lead to increased levels of CD300A and CXCL1 at the cellular level. Through bioinformatics analysis, machine learning algorithms, and experimental research, CD300A and CXCL1 are confirmed as both potential biomarkers in diabetic nephropathy. And we further revealed the main pathways of differential genes and the differentially distributed immune infiltrating cells in diabetic nephropathy.     

波前传感器电铸镍层应力实时检测精度评估

目的 搭建电铸应力实时检测平台，评估其测量精度，并探明电化学沉积过程中镍层平均内应力的变化规律。方法 采用横向剪切波前传感器搭建电铸应力实时检测平台，通过测量在铸层应力作用下电铸基底弯曲的曲率半径，利用Stoney公式计算铸层平均应力。采用参考球面反射镜评估横向剪切波前传感器曲率半径的测量精度，并在0.5 A/dm2电流密度下进行电铸应力实时检测实验，对铸层平均应力测量极限进行评估，同时对检测误差进行分析。结果 横向波前传感器曲率半径测量精度为99.22%，在0.5 A/dm2电流密度下，所搭建的铸层应力实时检测平台可测量的最小厚度为5.1 μm，由曲率测量波动带来的应力检测误差为1.3 MPa。实验测得铸层平均应力随铸层厚度的增加而变大，当铸层厚度达到30 μm左右，铸层平均应力趋于稳定，应力大小为79.7 MPa。同时发现，当铸层厚度小于30 μm时，沿电铸基底长度方向的铸层平均应力明显大于宽度方向铸层平均应力，随铸层厚度的增加，两个方向的应力大小趋于等值。结论 采用横向剪切波前传感器搭建的电铸应力检测平台，能有效对铸层应力进行高精度的实时测量，为精密电铸过程中应力变化规律的研究提供了检测技术基础。     

模糊数学在零件分组中的应用研究

在充分研究减法聚类法、模糊C均值聚类法和最大隶属度原则的基础上,针对机械零件分组中的模糊性,将以上的方法或者原则应用到其中,并结合工程实际情况作适当修改,使其更符合工程实际。通过实例验证了此方法的正确性和实用性,并分析了这种方法的优缺点。