Blends of Bio-Based Poly(Limonene Carbonate) with Commodity Polymers

In this study, blends of the bio-based poly(limonene carbonate) (PLimC) with different commodity polymers are investigated in order to explore the potential of PLimC toward generating more sustainable polymer materials by reducing the amount of petro- or food-based polymers. PLimC is employed as minority component in the blends. Next to the morphology and thermal properties of the blends the impact of PLimC on the mechanical properties of the matrix polymers is studied. The interplay of incompatibility and zero-shear melt viscosity contrast determines the blend morphology, leading for all blends to a dispersed droplet morphology for PLimC. Blends with polymers of similar structure to PLimC (i.e., aliphatic/aromatic polyester) show the best performance with respect to mechanical properties, whereas blends with polystyrene or poly(methyl methacrylate) are too brittle and polyamide 12 blends show very low elongations at break. In blends with Ecoflex (poly(butylene adipate-co-terephthalate)) and Arnitel EM400 (copoly(ether ester)) with poly(butylene terephthalate) hard and polytetrahydrofuran soft segments) a threefold increase in E-modulus can be achieved, while keeping the elongation at break at reasonable high values of ≈200%, making these blends highly interesting for applications.     

Extracellular Vesicles: Messengers of p53 in Tumor–Stroma Communication and Cancer Metastasis

Tumor progression to a metastatic and ultimately lethal stage relies on a tumor-supporting microenvironment that is generated by reciprocal communication between tumor and stromal host cells. The tumor–stroma crosstalk is instructed by the genetic alterations of the tumor cells—the most frequent being mutations in the gene Tumor protein p53 (TP53) that are clinically correlated with metastasis, drug resistance and poor patient survival. The crucial mediators of tumor–stroma communication are tumor-derived extracellular vesicles (EVs), in particular exosomes, which operate both locally within the primary tumor and in distant organs, at pre-metastatic niches as the future sites of metastasis. Here, we review how wild-type and mutant p53 proteins control the secretion, size, and especially the RNA and protein cargo of tumor-derived EVs. We highlight how EVs extend the cell-autonomous tumor suppressive activity of wild-type p53 into the tumor microenvironment (TME), and how mutant p53 proteins switch EVs into oncogenic messengers that reprogram tumor–host communication within the entire organism so as to promote metastatic tumor cell dissemination.     

The Nexus of Corporate Entrepreneurship and Radical Innovation

This paper explores the linkage between the entrepreneurial orientation of established firms and the development of radical innovation. Through five case studies in firms involved in radical innovation, three propositions are developed, suggesting that proactiveness, risk‐taking and autonomy stimulate the development of radical innovation, whereas competitive aggressiveness does not necessarily do so, as radical innovations are directed towards the creation of entirely new arenas of business, where existing competitors are not present.     

The polymerisation of 2-furyl vinyl ketone

Summary 2-Furyl vinyl ketone was polymerised using anionic, cationic and free-radical initiators. Yields and molecular weights varied with the type of activation. Whereas radical polymerisation gave a product possessing a regular vinylic structure, other kinds of units were detected in the polymers prepared with anionic and cationic catalysts.     

Gasification of Biogenic Solid Fuels

As a result of shrinking fossil fuels, biomass as a regenerative energy source gains importance. To realize biomass projects it is essential to investigate in convenient thermal procedures. On this evidence an analysis and evaluation of diverse gasification technologies with different boundary conditions and diverse biomasses are indispensable. Form and kind of the biomass as well as the type of the gasification plant cause different compositions of the product gas. The gasifiers show advantages and disadvantages concerning the biomass and the produced gas quality, depending on reactor type, kind of heat supply, gasification medium, and the pressure ratio in the reactor. As the ideal gasifier for different biomass is presently not available, it will be shown, which biomass is suitable for fixed bed or fluidized bed gasifiers.     

Bone SPECT of the jaws after fracture, onlay osteoplasty of insertion of implants

AIM: The aim of this study was early differentiation between uncomplicated and complicated processes of healing in the jaw using bone SPECT. METHODS: Investigations were performed in 40 mandibular fractures and 26 jaws after onlay osteoplasty as well as secondary insertion of implants. Bone SPECT was carried out within 1-2 months and after approximately 4-5 months. The uptake in the jaw was assessed semi-quantitatively using ROI analysis. RESULTS: Fractures with uncomplicated healing showed a decrease of uptake in follow-up, whereas fractures with an infection in the later course showed an increase, resulting in a significantly higher uptake at the follow-up investigation for the latter group. 1-2 months after onlay osteoplasty significantly lower uptake was found in regions with later occurrence of sequestration. In regions with implants in which osseointegration failed, there was significant reduction of uptake initially and significant elevation at the follow-up investigation. CONCLUSION: These results indicate a prognostic relevance of bone SPECT in the evaluation of processes of healing in the jaw.     

快重离子在石墨中引起表面及体径迹的STM研究

用多种快重离子辐照高定向石墨（HOPG），借助扫描隧道显微镜（STM）系统地研究了表面及体内缺陷，结果表明，离子在表面及解理面上都形成了小丘状的缺陷，且在表面较容易形成，可以用非连续损伤径迹结构来对其进行解释。     

Vapor-phase viscosity of phenol

New measurements of the vapor-phase viscosity of phenol were performed from 437 up to 624 K and for densities between 0.006 and 0.023 mol · L^–1 in an all-quartz oscillating-disk viscometer with small gaps. Thus, including our own measurements reported earlier, experimental data are available in the temperature range between 376 and 639 K and in the density range from 0.001 up to 0.023 mol · L^–1. The data were evaluated with a density series for the viscosity in which only a linear density contribution is included. The values of the second viscosity virial coefficient obtained for phenol as well as for benzene, toluene, and p-xylene were compared with results of the Rainwater-Friend theory and of the modified Enskog theory on the basis of the Lennard-Jones 12-6 potential. The agreement is reasonable, when the potential parameter ratios determined by Bich and Vogel are used. The influence of bound dimers seems to be already taken into account in the three-monomer contribution according to Hoffman and Curtiss.Paper dedicated to Professor Joseph Kestin.