Designing optical glasses by machine learning coupled with a genetic algorithm

Engineering new glass compositions have experienced a sturdy tendency to move forward from (educated) trial-and-error to data- and simulation-driven strategies. In this work, we developed a computer program that combines data-driven predictive models (in this case, neural networks) with a genetic algorithm to design glass compositions with desired combinations of properties. First, we induced predictive models for the glass transition temperature (T_g) using a dataset of 45,302 compositions with 39 different chemical elements, and for the refractive index (n_d) using a dataset of 41,225 compositions with 38 different chemical elements. Then, we searched for relevant glass compositions using a genetic algorithm informed by a design trend of glasses having high n_d (1.7 or more) and low T_g (500 °C or less). Two candidate compositions suggested by the combined algorithms were selected and produced in the laboratory. These compositions are significantly different from those in the datasets used to induce the predictive models, showing that the used method is indeed capable of exploration. Both glasses met the constraints of the work, which supports the proposed framework. Therefore, this new tool can be immediately used for accelerating the design of new glasses. These results are a stepping stone in the pathway of machine learning-guided design of novel glasses.     

Two-step sinter-crystallization of K2O–CaO–P2O5–SiO2 (45S5-K) bioactive glass

Bioactive glasses and glass-ceramics (GCs) effectively regenerate bone tissue, however most GCs show improved mechanical properties. In this work, we developed and tested a rarely studied bioactive glass composition (24.4K₂O-26.9CaO-46.1SiO₂-2.6P₂O₅ mol%, identified as 45S5-K) with different particle sizes and heating rates to obtain a sintered GC that combines good fracture strength, low elastic modulus, and bioactivity. We analyzed the influence of the sintering processing conditions in the elastic modulus, Vickers microhardness, density, and crystal phase formation in the GC. The best GC shows improved properties compared with its parent glass. This glass achieves a good densification degree with a two-step viscous flow sintering approach and the resulting GC shows as high bioactivity as that of the standard 45S5 Bioglass®. Furthermore, the GC elastic modulus (56 GPa) is relatively low, minimizing stress shielding. Therefore, we unveiled the glass sintering behavior with concurrent crystallization of this complex bioactive glass composition and developed a potential GC for bone regeneration.     

The control of sea lice in Atlantic salmon by selective breeding

Sea lice threaten the welfare of farmed Atlantic salmon and the sustainability of fish farming across the world. Chemical treatments are the major method of control but drug resistance means that alternatives are urgently needed. Selective breeding can be a cheap and effective alternative. Here, we combine experimental trials and diagnostics to provide a practical protocol for quantifying resistance to sea lice. We then combined quantitative genetics with epidemiological modelling to make the first prediction of the response to selection, quantified in terms of reduced need for chemical treatments. We infected over 1400 young fish with Lepeophtheirus salmonis, the most important species in the Northern Hemisphere. Mechanisms of resistance were expressed early in infection. Consequently, the number of lice per fish and the ranking of families were very similar at 7 and 17 days post infection, providing a stable window for assessing susceptibility to infection. The heritability of lice numbers within this time window was moderately high at 0.3, confirming that selective breeding is viable. We combined an epidemiological model of sea lice infection and control on a salmon farm with genetic variation in susceptibility among individuals. We simulated 10 generations of selective breeding and examined the frequency of treatments needed to control infection. Our model predicted that substantially fewer chemical treatments are needed to control lice outbreaks in selected populations and chemical treatment could be unnecessary after 10 generations of selection. Selective breeding for sea lice resistance should reduce the impact of sea lice on fish health and thus substantially improve the sustainability of Atlantic salmon production.     

硬件锁中的无线USB

无线USB的前途似乎无与伦比——它能消除那些把大家桌面弄得像鼠窝一样小小的不怎么灵便的电缆。但事实上,只有需要大量的外设时无线USB设备才有优势,而且它必须非常微型而廉价,否则带来的麻烦远多于缠绕的电缆。因此,插在PC USB端口作为无线基站的硬件锁就必须有尽可能高的集成度。但一片芯片中要包含USB有线接口、控制器、无线基带和RF电路,技术上还无法实现。下面我们将看到一家供应商Wisalr的一种可量产参考设计,它是如何接近于解决这个问题的。     

Space-dependent color gamut mapping: a variational approach.

Gamut mapping deals with the need to adjust a color image to fit into the constrained color gamut of a given rendering medium. A typical use for this tool is the reproduction of a color image prior to its printing, such that it exploits best the given printer/medium color gamut, namely the colors the printer can produce on the given medium. Most of the classical gamut mapping methods involve a pixel-by-pixel mapping and ignore the spatial color configuration. Recently proposed spatial-dependent approaches for gamut mapping are either based on heuristic assumptions or involve a high computational cost. In this paper, we present a new variational approach for space-dependent gamut mapping. Our treatment starts with the presentation of a new measure for the problem, closely related to a recent measure proposed for Retinex. We also link our method to recent measures that attempt to couple spectral and spatial perceptual measures. It is shown that the gamut mapping problem leads to a quadratic programming formulation, guaranteed to have a unique solution if the gamut of the target device is convex. An efficient numerical solution is proposed with promising results.     

对电压参考进行滤波以获得低噪声性能

输出电压相对于电压参考的短期变化即为噪声。参考电压噪声一般发生在以下两个频段：短期噪声在0．1Hz～10Hz，宽带噪声在10Hz～1kHz。由于噪声电压一般与参考电压成正比，故常用每百万分之一（ppm）来表示噪声，并借此使每百万分之一值恒定。能隙（或带隙）电压参考具有介于3ppm～16ppm之间的噪声电压，但埋入式齐纳电压参考的噪声更低，介于0．1ppm～0．5ppm之间。噪声随参考电流的增加而减小，但增加参考电流并不是大多数电压参考的选项。     

Effect of beam voltage on the properties of aluminium nitride prepared by ion beam assisted deposition

The effects of nitrogen-beam voltage on the structure, stress, energy band gap and hardness of AIN thin films deposited on Si (111), Si (100) and sapphire (0001) by ion beam assisted deposition (IBAD) are reported. As the nitrogen-beam voltage was increased from 50 to 200 V, the stress and disorder in the AIN films increased as determined by X-ray diffraction, FTIR and Raman spectroscopy. The preferred orientation of the film's c-axis changed from completely normal to the film at 100 V, to a mixture of normal and in the plane of the film at 200 V. For AIN films deposited under the same conditions, the films were more highly oriented on sapphire (0001) than in Si (111). The hardness of the films increased from 18.2 to 23.7 GPa with the nitrogen-beam voltage, and possible reasons for this change in hardness are considered.     

Complete forward displacement solutions for a class of three-branch parallel manipulators

Forward displacement solutions are presented for a class of spatial parallel manipulators. In particular, considered are manipulators consisting of a platform supported through passive spherical joints by three branches, each branch having three-revolute joints forming its main arm. Solutions are described for arbitrary main-arm layouts and for all possible cases of redundant (nine, eight, and seven sensors) and non-redundant (six sensors) sensing of branch main-arm joint displacements. It is demonstrated that closed-form forward displacement solutions can be found for all cases of redundant sensing. Furthermore, it is shown that a closed-form solution can be obtained for one of the two possible cases of non-redundant sensing of the main-arm joint displacements. The only case of joint displacement sensing not allowing a closed-form forward displacement solution is two joints sensed per branch, a case that can be expressed as a 16th-order polynomial of a single variable. Due to the importance of having efficient and failure-safe solutions for the forward displacement problem, it is suggested that appropriate redundancy in displacement sensing should be an important consideration in the design of parallel manipulation devices. © 1994 John Wiley & Sons, Inc.