Contracting, prompting, and reinforcing substance use disorder continuing care: A randomized clinical trial.

Although continuing care is strongly related to positive treatment outcomes for substance use disorder (SUD), participation rates are low and few effective interventions are available. In a randomized clinical trial with 150 participants (97% men), 75 graduates of a residential Veterans Affairs Medical Center SUD program who received an aftercare contract, attendance prompts, and reinforcers (CPR) were compared to 75 graduates who received standard treatment (STX). Among CPR participants, 55% completed at least 3 months of aftercare, compared to 36% in STX. Similarly, CPR participants remained in treatment longer than those in STX (5.5 vs. 4.4 months). Additionally, CPR participants were more likely to be abstinent compared to STX (57% vs. 37%) after 1 year. The CPR intervention offers a practical means to improve adherence among individuals in SUD treatment. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Cost effective second generation AC-modules: Development and testing aspects

In the framework of the European research project PV2GO, a new AC-module inverter was developed, taking into account all relevant aspects from a European market's point of view (standards, market, application, and research and development goals). The project goal was to achieve the overall system costs of 3 Euro per Wp for a modular plug-and-play photovoltaic system. For the photovoltaic-module, a standard 130-Wp Eurosolare module was chosen. The research and development (R&D) goal was to develop an advanced DC-control system consisting of a state-of-the-art programmable digital device and an Application Specific Integrated Circuit (ASIC) for the AC-control of the inverter. According to the topology concept, thermal and magnetic designs were optimized with regard to production technology and packaging for large-scale production. The new AC-modules were tested in a number of field-test sites in various parts of Europe and their reliability was assessed through Highly Accelerated Stress Tests. Efficiency and power quality have been tested in the laboratory. Further in the PV2GO project an optimization study of the manufacturing process of the new generation of AC-modules for high volume output was done. Another task was the pre-certification procedure to assure compliance with the European guidelines and standards.     

IT Service Climate—An Essential Managerial Tool to Improve Client Satisfaction With IT Service Quality

Although client satisfaction surveys can assess client satisfaction with IT service quality, they cannot easily be used to pinpoint how internal IT behaviors influence client satisfaction and prescribe solutions. This research fills the gap by introducing a concept— IT Service Climate—and a validated ten-item instrument that significantly explained client ratings of IT service quality. We recommend this measure as an effective diagnostic tool for managers aiming to improve quality and client satisfaction.     

Bag the sags

This article describes the vulnerability of variable speed drives (VSD) to voltage sags on a theoretical basis. Then, three embedded mitigation methods are addressed in theory which protect textile processes against voltage sags, and practical measurements with a sag generator are shown. The use of embedded solutions such as kinetic buffering and boost convertor or an active front end will increase the voltage sag immunity of the process. Finally, two processes in the textile industry are described, and a brief cost-benefit analysis of the solutions is made. Experiments with a sag generator show that the voltage sag behaviour can be well described by theoretical models.     

Nanoparticulate Delivery of Cancer Cell Membrane Elicits Multiantigenic Antitumor Immunity

Anticancer vaccines train the body's own immune system to recognize and eliminate malignant cells based on differential antigen expression. While conceptually attractive, clinical efficacy is lacking given several key challenges stemming from the similarities between cancerous and healthy tissue. Ideally, an effective vaccine formulation would deliver multiple tumor antigens in a fashion that potently stimulates endogenous immune responses against those antigens. Here, it is reported on the fabrication of a biomimetic, nanoparticulate anticancer vaccine that is capable of delivering autologously derived tumor antigen material together with a highly immunostimulatory adjuvant. The two major components, tumor antigens and adjuvant, are presented concurrently in a fashion that maximizes their ability to promote effective antigen presentation and activation of downstream immune processes. Ultimately, it is demonstrated that the formulation can elicit potent antitumor immune responses in vivo. When combined with additional immunotherapies such as checkpoint blockades, the nanovaccine demonstrates substantial therapeutic effect. Overall, the work represents the rational application of nanotechnology for immunoengineering and can provide a blueprint for the future development of personalized, autologous anticancer vaccines with broad applicability.     

Towards an international tradable green certificate system—The challenging example of Belgium

In Europe, a common framework for renewable energy sources (RES) is aspired. Tradable green certificates (TGCs) are a market-based cost-efficient means to stimulate electricity production from RES. Since TGCs are the most widespread support scheme in Europe together with feed-in tariffs, chances are that a common European framework could well be based on TGCs. However, while integrating currently existing different national TGC systems, any remaining differences should be carefully considered. Just how difficult the creation of an international TGC market would be is illustrated in this paper by the case of Belgium, where no less than 4 different TGC systems exist nowadays. The example of Belgium illustrates that harmonizing different TGC systems is easier said than done and represents a serious challenge. This clearly illustrates that a single European support scheme for RES, however desirable, is still far in the future.     

Electro-mechanical analysis of the audible noise of an inverter-fedsquirrel-cage induction motor

The audible noise emitted by a three-phase squirrel cage induction motor fed by a frequency inverter is determined by the electromagnetic and mechanical behavior of the components of the drive. A computerized analysis method is described that uses theoretical and experimental data for predicting the audible noise spectrum components. Starting from the inverter voltage and the motor data, the electromagnetic forces are predicted and analyzed. The mechanical natural frequencies are considered, either in a theoretical (finite element calculation) or in an experimental (modal analysis) methodology, to predict the vibrational behavior of the machine. The scheme contains the following steps: analysis of the frequency spectrum of the inverter used; synthesis of the magnetic force spectrum accounting for the motor data: calculation or measurement of the resonant data of the stator assembly; and comparison of the force spectrum and the resonant data. These various steps are discussed     

A Voltage and Frequency Droop Control Method for Parallel Inverters

In this paper, a new control method for the parallel operation of inverters operating in an island grid or connected to an infinite bus is described. Frequency and voltage control, including mitigation of voltage harmonics, are achieved without the need for any common control circuitry or communication between inverters. Each inverter supplies a current that is the result of the voltage difference between a reference ac voltage source and the grid voltage across a virtual complex impedance. The reference ac voltage source is synchronized with the grid, with a phase shift, depending on the difference between rated and actual grid frequency. A detailed analysis shows that this approach has a superior behavior compared to existing methods, regarding the mitigation of voltage harmonics, short-circuit behavior and the effectiveness of the frequency and voltage control, as it takes the R to X line impedance ratio into account. Experiments show the behavior of the method for an inverter feeding a highly nonlinear load and during the connection of two parallel inverters in operation.