全文获取类型
收费全文 | 124篇 |
免费 | 2篇 |
国内免费 | 1篇 |
专业分类
电工技术 | 5篇 |
化学工业 | 38篇 |
金属工艺 | 1篇 |
机械仪表 | 1篇 |
建筑科学 | 3篇 |
能源动力 | 20篇 |
轻工业 | 13篇 |
水利工程 | 1篇 |
无线电 | 5篇 |
一般工业技术 | 11篇 |
冶金工业 | 14篇 |
原子能技术 | 1篇 |
自动化技术 | 14篇 |
出版年
2023年 | 1篇 |
2021年 | 9篇 |
2020年 | 4篇 |
2018年 | 3篇 |
2017年 | 2篇 |
2016年 | 4篇 |
2015年 | 1篇 |
2014年 | 2篇 |
2013年 | 10篇 |
2012年 | 4篇 |
2011年 | 3篇 |
2010年 | 7篇 |
2009年 | 2篇 |
2008年 | 3篇 |
2007年 | 4篇 |
2006年 | 9篇 |
2005年 | 5篇 |
2004年 | 3篇 |
2003年 | 2篇 |
2002年 | 3篇 |
2001年 | 1篇 |
2000年 | 2篇 |
1999年 | 5篇 |
1998年 | 4篇 |
1997年 | 3篇 |
1996年 | 1篇 |
1995年 | 4篇 |
1994年 | 2篇 |
1993年 | 3篇 |
1992年 | 1篇 |
1991年 | 1篇 |
1990年 | 2篇 |
1988年 | 3篇 |
1986年 | 1篇 |
1984年 | 4篇 |
1983年 | 2篇 |
1982年 | 2篇 |
1978年 | 1篇 |
1977年 | 1篇 |
1976年 | 2篇 |
1971年 | 1篇 |
排序方式: 共有127条查询结果,搜索用时 859 毫秒
1.
Mechanical alloying of polymer/metal systems 总被引:2,自引:0,他引:2
2.
Asako Yamamoto Lingli Yang Yasutaka Kuroda Jiao Guo Lanting Teng Daisuke Tsuruta Ichiro Katayama 《International journal of molecular sciences》2021,22(1)
As the outermost barrier of the body, skin is a major target of oxidative stress. In the brain, estrogen has been reported synthesized locally and protects neurons from oxidative stress. Here, we explored whether estrogen is also locally synthesized in the skin to protect from oxidative stress and whether aberrant local estrogen synthesis is involved in skin disorders. Enzymes and estrogen receptor expression in skin cells were examined first by quantitative real-time PCR and Western blot analyses. Interestingly, the estrogen synthesis enzyme was mainly localized in epidermal keratinocytes and estrogen receptors were mainly expressed in melanocytes among 13 kinds of cultured human skin cells. The most abundant estrogen synthesis enzyme expressed in the epidermis was 17β-hydroxysteroid dehydrogenase 1 (HSD17β1) localized in keratinocytes, and the most dominant estrogen receptor expressed in the epidermis was G protein-coupled estrogen receptor 1 (GPER1) in melanocytes. To investigate whether keratinocyte-derived estradiol could protect melanocytes from oxidative stress, cultured human primary epidermal melanocytes (HEMn-MPs) were treated with H2O2 in the presence or absence of 17β estradiol or co-cultured with HSD17β1 siRNA-transfected keratinocytes. Keratinocyte-derived estradiol exhibited protective effects against H2O2-induced cell death. Further, reduced expression of HSD17β1 in the epidermis of skin from vitiligo patients was observed compared to the skin from healthy donors or in the normal portions of the skin in vitiligo patients. Our results suggest a possible new target for interventions that may be used in combination with current therapies for patients with vitiligo. 相似文献
3.
S. Takadono H. Iwahori T. Yabushita Y. Imamura H. Ishizuka S. Tamaru 《Desalination》1984,49(3):347-355
Membrane fouling by suspended solids is a severe problem in reverse osmosis or ultrafiltration of highly fouling feed streams. Tubular membrane systems are inherently fouling resistant and can be automatically mechanically cleaned at regular intervals by a sponge ball cleaning device. The use of this type of system to process a number of highly fouling feed streams difficult to treat by membrane processes is described 相似文献
4.
Summary CP/DD/MASS 13C-NMR spectra have been obtained for regenerated cellulose samples with different crystallinities as well as for cotton, -D-glucose, -D-cellobiose, and cellopentaose. The spectra of the regenerated cellulose samples exhibit broad multiplicities of the C-4 and C-6 resonance lines in a similar manner as those of native cellulose samples such as cotton and ramie, and, in addition, another broad tailing of the C-1 resonance. Since these multiplicities change linearly with crystallinity, it is concluded that they are ascribed to the contributions from the crystalline and noncrystalline components. Effects of hydrogen bonds and conformations of the -1,4-glycosidic linkage on the chemical shifts are also discussed. 相似文献
5.
6.
This study aimed at investigating the effect of drying conditions on spaghetti properties, i.e., its color, surface structure, rupture strength, rehydration characteristics, texture, and sauce retention capacity. The effects of temperature and humidity were independently examined under constant drying conditions, which were compared to those applied industrially, where the temperature and relative humidity are changed stepwise with time. The knowledge obtained in this study is considered useful for reasonably determining the drying conditions for producing spaghetti with desired properties. 相似文献
7.
Daisuke Kawashima Yutaka Asako 《International Journal of Heat and Mass Transfer》2012,55(9-10):2244-2248
This paper focuses on temperature rise due to the viscous dissipation in liquids flowing through micro-channels. In the past, equations for the prediction of the temperature rise have been obtained as a function of the friction factor, Reynolds number and Eckert number or a similar form, starting from Navier–Stokes equation and energy equation under the assumption of fully developed laminar flow by researchers. The temperature rises calculated from the equations have been compared with experimental data and the equations have been validated. However, in this paper, a new equation for the prediction of the temperature rise is simply obtained from the first law of thermodynamics without restriction of fully developed laminar flow. 相似文献
8.
Ishikawa H Tamaru H Miyano K 《Journal of the Optical Society of America. A, Optics, image science, and vision》2000,17(4):802-813
A model is proposed that describes the essential optical process in the recently observed resonant light scattering from a microsphere resonator that is strongly coupled to the substrate. The experimentally observed field patterns across the resonance can be reproduced quite well by a numerical calculation taking into account only a few vector spherical waves that are converted from nonpropagating to propagating waves at the substrate surface. Explicit consideration of the multiple-reflection effect is not necessary to reproduce the experimental results. Comparison of the experiment and the calculation suggests the splitting of degenerate resonance modes that have different azimuthal mode numbers within a single broad resonance line. These results are discussed on the basis of the strongly coupled nature of the system. 相似文献
9.
Daiki Uryu Tomohiro Tamaru Azusa Suzuki Rie Sakai 《Science and Technology of Advanced Materials》2016,17(1):691-697
The establishment and maintenance of axonal patterning is crucial for neuronal function. To identify the molecular systems that operate locally to control axonal structure, it is important to manipulate molecular functions in restricted subcellular areas for a long period of time. Microfluidic devices can be powerful tools for such purposes. In this study, we demonstrate the application of a microfluidic device to clarify the function of local Ca2+ signals in axons. Membrane depolarization significantly induced axonal branch-extension in cultured cerebellar granule neurons (CGNs). Local application of nifedipine using a polydimethylsiloxane (PDMS)-based microfluidic device demonstrated that Ca2+ entry from the axonal region via L-type voltage-dependent calcium channels (L-VDCC) is required for branch extension. Furthermore, we developed a method for locally controlling protein levels by combining genetic techniques and use of a microfluidic culture system. A vector for enhanced green fluorescent protein (EGFP) fused to a destabilizing domain derived from E. coli dihydrofolate reductase (ecDHFR) is introduced in neurons by electroporation. By local application of the DHFR ligand, trimethoprim (TMP) using a microfluidic device, we were able to manipulate differentially the level of fusion protein between axons and somatodendrites. The present study revealed the effectiveness of microfluidic devices to address fundamental biological issues at subcellular levels, and the possibility of their development in combination with molecular techniques. 相似文献
10.
Sobi Asako Takahisa Sakae Masahito Murai Kazuhiko Takai 《Advanced Synthesis \u0026amp; Catalysis》2016,358(24):3966-3970
Mild and simple catalytic systems consisting of molybdenum(VI) dichloride dioxide [MoO2Cl2] as a catalyst and a phosphine as reductant have been developed for the stereospecific deoxygenation of epoxides to alkenes. The reactions using 1,2‐bis(diphenylphosphino)ethane (dppe) and triphenylphosphine (PPh3) proceed with retention and inversion of stereochemistry, respectively. The mild reaction tolerates the presence of various functional groups and affords stereodefined substituted olefins in good yields.