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Although Governance, Risk and Compliance (GRC) is an emerging field of study within the information systems (IS) academic community, the concept behind the acronym has to still be demystified and further investigated. The study investigates GRC systems in depth by (a) reviewing the literature on existing GRC studies, and (b) presenting a field study on views about GRC application by professional experts. The aim of this exploratory study is to understand the aspects and the nature of the GRC system following an enterprise systems approach. The result of this study is a framework of particular GRC characteristics that need to be taken into consideration when these systems are put in place. This framework includes specific areas such as: goals and objectives, purpose of the system, key stakeholders, methodology and requirements prior to implementation, critical success factors and problems/barriers. Further discussion about the issues, the concerns and the diverse views on GRC would assist in developing an agenda for the future research on the GRC field.  相似文献   
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This study monitors variations in isotopes and elements in relation to grape variety, environmental factors and provenance in order to address the wine authenticity issue. Inductively coupled plasma atomic emission spectroscopy (ICP-AES) assessed the wines’ elemental content. Site-specific nuclear isotope fractionation-nuclear magnetic resonance and isotope ratio mass spectrometry methodologies determined in authentic and commercial wines the distribution of the naturally occurring stable isotopes of the deuterium/hydrogen (D/H) ratios and carbon (13C/12C) in ethanol of wine and oxygen ratio (18O/16O) in wine water. Chemometrics delineated the elements and isotopes responsible for wine classification. Specifically, unsupervised principal component analysis (PCA) framed the importance of grape variety and provenance, while supervised analysis pinpointed the vineyard effect and highlighted the contribution of the vintage year. Validation steps ensured that the extracted models do not predict randomly and their results are reliable. In fact, the acquired results can be incorporated to the EU Wine Isotopic Databank database providing both a guide and a tool for eventual candidatures for denomination of origin and support both Cypriot wine and winemakers. In this context, this research contributes to authenticity assurance of wines and adds value to final products, while it helps controlling hazards arising from environmental changes.  相似文献   
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This paper constitutes a literature review on student modeling for the last decade. The review aims at answering three basic questions on student modeling: what to model, how and why. The prevailing student modeling approaches that have been used in the past 10 years are described, the aspects of students’ characteristics that were taken into consideration are presented and how a student model can be used in order to provide adaptivity and personalisation in computer-based educational software is highlighted. This paper aims to provide important information to researchers, educators and software developers of computer-based educational software ranging from e-learning and mobile learning systems to educational games including stand alone educational applications and intelligent tutoring systems. In addition, this paper can be used as a guide for making decisions about the techniques that should be adopted when designing a student model for an adaptive tutoring system. One significant conclusion is that the most preferred technique for representing the student’s mastery of knowledge is the overlay approach. Also, stereotyping seems to be ideal for modeling students’ learning styles and preferences. Furthermore, affective student modeling has had a rapid growth over the past years, while it has been noticed an increase in the adoption of fuzzy techniques and Bayesian networks in order to deal the uncertainty of student modeling.  相似文献   
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In the present study, complexes of vanillin with β-cyclodextrin (β-CD) were prepared by the freeze-drying method. The formation of the inclusion complex was confirmed by differential scanning calorimetry (DSC). DSC thermograms indicated that the endothermic peak of vanillin and the physical mixture of vanillin with β-CD, due to the melting of vanillin crystals, were absent in DSC thermograms obtained for the freeze-dried inclusion complex. Moreover, the DSC studies under oxidation conditions indicate that the complex of vanillin with β-CD is protected towards oxidation since it remains intact at temperatures where the free vanillin is oxidising. The structure of the complex in aqueous solutions was established by nuclear magnetic resonance (NMR) studies and specifically by two-dimensional rotational frame NOE spectra. NMR studies showed inclusion of the entire vanillin molecule in the β-CD in a tilted manner and with the aldehyde group in the primary side. The stoichiometry of the complex was 1:1. A phase solubility study was performed by mixing an excess amount of vanillin with aqueous solutions containing increasing amounts of β-CD. The results indicated that the complex of a vanillin/β-CD inclusion is more soluble in water than vanillin alone.  相似文献   
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The objectives of the present study were (a) to produce gluten-free bread, fortified with iron (GFB-Fe), using selected iron compounds (ferric pyrophosphate, ferric pyrophosphate with emulsifiers, NaFeEDTA, electrolytic iron, ferrous gluconate, ferrous lactate and ferrous sulphate) (b) to test sensory characteristics of the GFB-Fe (feel-mouth texture, crumb colour, aroma and taste) (c) to compare iron dialyzability of various iron compounds in GFB-Fe. The most acceptable products were those fortified with ferric pyrophosphate with emulsifiers and ferric pyrophosphate. Ferrous dialyzable iron (ferrous iron with molecular weight lower than 8000 Da, an index for prediction of iron bioavailability) was measured under simulated gastrointestinal conditions. Ferrous dialyzable iron in GFB-Fe fortified with ferric pyrophosphate with emulsifiers, NaFeEDTA, ferrous bis-glycinate, ferrous gluconate or ferrous sulphate was higher than that in GFB-Fe fortified with electrolytic iron, ferrous lactate or ferric pyrophosphate (P < 0.05). These results are promising for the development of GFB-Fe products in the future.  相似文献   
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We present a patient with primary systemic AL‐amyloidosis, who stabilized hemodynamically on nocturnal hemodialysis (NHD). The NHD allowed a significant reduction in ultrafiltration rates which likely underlies the procedural tolerability. It also provided an increase in urea clearance, better control of serum phosphorus levels without the use of any binders, and normalization of blood pressure despite the discontinuation of all antihypertensive agents. Given the autonomic derangements associated with AL‐amyloidosis pathophysiology and the clinical benefits of NHD on hemodynamic stability, the use of intensive hemodialysis may be considered for the management of patients with unstable hemodynamic profiles.  相似文献   
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