Etching characteristics of thin SiON films using a liquefied perfluorocarbon precursor of C6F12O with a low global warming potential

Perfluorocarbon gas is widely used in the semiconductor industry. However, perfluorocarbon has a negative effect on the global environment owing to its high global warming potential (GWP) value. An alternative solution is essential. Therefore, we evaluated the possibility of replacing conventional perfluorocarbon etching gases such as CHF₃ with C₆F₁₂O, which has a low GWP and is in a liquid state at room temperature. In this study, silicon oxynitride (SiON) films were plasma-etched using inductively coupled CF₄ +C₆F₁₂O+O₂ mixed plasmas. Subsequently, the etching characteristics of the film, such as etching rate, etching profile, selectivity over Si, and photoresist, were investigated. A double Langmuir probe was used and optical emission spectroscopy was performed for plasma diagnostics. In addition, a contact angle goniometer and x-ray photoelectron spectroscope were used to confirm the change in the surface properties of the etched SiON film surface. Consequently, the etching characteristics of the C₆F₁₂O mixed plasma exhibited a lower etching rate, higher SiON/Si selectivity, lower plasma damage, and more vertical etched profiles than the conventional CHF₃ mixed plasma. In addition, the C₆F₁₂O gas can be recovered in the liquid state, thereby decreasing global warming. These results confirmed that the C₆F₁₂O precursor can sufficiently replace the conventional etching gas.     

A connection rule for alpha-carbon coarse-grained elastic network models using chemical bond information

A sparser but more efficient connection rule (called a bond-cutoff method) for a simplified alpha-carbon coarse-grained elastic network model is presented. One of conventional connection rules for elastic network models is the distance-cutoff method, where virtual springs connect an alpha-carbon with all neighbor alpha-carbons within predefined distance-cutoff value. However, though the maximum interaction distance between alpha-carbons is reported as 7 angstroms, this cutoff value can make the elastic network unstable in many cases of protein structures. Thus, a larger cutoff value (>11 angstroms) is often used to establish a stable elastic network model in previous researches. To overcome this problem, a connection rule for backbone model is proposed, which satisfies the minimum condition to stabilize an elastic network. Based on the backbone connections, each type of chemical interactions is considered and added to the elastic network model: disulfide bonds, hydrogen bonds, and salt-bridges. In addition, the van der Waals forces between alpha-carbons are modeled by using the distance-cutoff method. With the proposed connection rule, one can make an elastic network model with less than 7 angstroms distance cutoff, which can reveal protein flexibility more sharply. Moreover, the normal modes from the new elastic network model can reflect conformational changes of a given protein better than ones by the distance-cutoff method. This method can save the computational cost when calculating normal modes of a given protein structure, because it can reduce the total number of connections. As a validation, six example proteins are tested. Computational times and the overlap values between the conformational change and infinitesimal motion calculated by normal mode analysis are presented. Those animations are also available at UMass Morph Server (http://biomechanics.ecs.umass.edu/umms.html).     

Study on photocatalysis of TiO 2 nanotubes prepared by methanol-thermal synthesis at low temperature

TiO₂ nanotubes were synthesized by the solvothermal process at low temperature in a highly alkaline water–methanol mixed solution. Their characteristics were identified by powder X-ray diffraction (XRD), transmission electron microscopy (TEM), specific surface area (BET), Fourier transform infrared spectroscopy (FTIR) and UV–Vis absorption spectroscopy. The as-prepared samples were tested by the photodegradation reaction of methylene blue (MB) dye under visible-light irradiation. The ratios of methanol and water, as well as calcination temperature, affected the morphology, nanostructure and photocatalytic performance. The methanol solvent plays an important role in improving crystallization of the anatase phase, which affects the photocatalytic reaction. Titanate nanotubes were synthesized in methanol–water volume ratios of 10:90, 20:80 and 30:70 which still had high absorbability. Titania nanotubes formed at a calcination temperature of 300 °C using methanol–water volume ratio of 30:70 showed highest photocatalytic performance, much higher than that using water solvent and TiO₂–P25 powder.     

Directed test suite augmentation: an empirical investigation

Test suite augmentation techniques are used in regression testing to identify code elements in a modified program that are not adequately tested and to generate test cases to cover those elements. A defining feature of test suite augmentation techniques is the potential for reusing existing regression test suites. Our preliminary work suggests that several factors influence the efficiency and effectiveness of augmentation techniques that perform such reuse. These include the order in which target code elements are considered while generating test cases, the manner in which existing regression test cases and newly generated test cases are used, and the algorithm used to generate test cases. In this work, we present the results of two empirical studies examining these factors, considering two test case generation algorithms (concolic and genetic). The results of our studies show that the primary factor affecting augmentation using these approaches is the test case generation algorithm utilized; this affects both cost and effectiveness. The manner in which existing and newly generated test cases are utilized also has a substantial effect on efficiency and in some cases a substantial effect on effectiveness. The order in which target code elements are considered turns out to have relatively few effects when using concolic test case generation but in some cases influences the efficiency of genetic test case generation. The results of our first study, on four relatively small programs using a large number of test suites, are supported by our second study of a much larger program available in multiple versions. Together, the studies reveal a potential opportunity for creating a more cost‐effective hybrid augmentation approach leveraging both concolic and genetic test case generation techniques, while appropriately utilizing our understanding of the factors that affect them. Copyright © 2014 John Wiley & Sons, Ltd.     

An experimental evaluation of a residential-sized evaporatively cooled condenser

In this paper, the performance of an innovative evaporatively cooled condenser is compared with that of a conventional air-cooled condenser for a split heat pump system. The system was tested in an environmentally controlled test chamber that was able to simulate test conditions as specified by ASHRAE Standard 116. Tests to optimize refrigerant charge and short tube restrictor size were conducted using refrigerant HCFC-22. The wheel rotation speed of the evaporative condenser was also optimized experimentally to maximize the coefficient of performance. Using these optimum parameters, steady state and cyclic performance tests were conducted. The experimental results showed that the evaporative condenser has a higher capacity than the air-cooled condenser by 1.8 to 8.1%, a higher COP by 11.1 to 21.6%, and a higher SEER by 14.5%.     

Crystal Structure,Chemical Bonding and Magnetism Studies for Three Quinary Polar Intermetallic Compounds in the (Eu1?xCax)9In8(Ge1?ySny)8 (x = 0.66, y = 0.03) and the (Eu1?xCax)3In(Ge3?ySn1+y) (x = 0.66, 0.68; y = 0.13, 0.27) Phases

Three quinary polar intermetallic compounds in the (Eu_1−xCa_x)₉In₈(Ge_1−ySn_y)₈ (x = 0.66, y = 0.03) and the (Eu_1−xCa_x)₃In(Ge_3-ySn_1+y) (x = 0.66, 0.68; y = 0.13, 0.27) phases have been synthesized using the molten In-metal flux method, and the crystal structures are characterized by powder and single-crystal X-ray diffractions. Two orthorhombic structural types can be viewed as an assembly of polyanionic frameworks consisting of the In(Ge/Sn)₄ tetrahedral chains, the bridging Ge₂ dimers, either the annulene-like “12-membered rings” for the (Eu_1−xCa_x)₉In₈(Ge_1−ySn_y)₈ series or the cis-trans Ge/Sn-chains for the (Eu_1−xCa_x)₃In(Ge_3−ySn_1+y) series, and several Eu/Ca-mixed cations. The most noticeable difference between two structural types is the amount and the location of the Sn-substitution for Ge: only a partial substitution (11%) occurs at the In(Ge/Sn)₄ tetrahedron in the (Eu_1−xCa_x)₉In₈(Ge_1−ySn_y)₈ series, whereas both a complete and a partial substitution (up to 27%) are observed, respectively, at the cis-trans Ge/Sn-chain and at the In(Ge/Sn)₄ tetrahedron in the (Eu_1−xCa_x)₃In(Ge_3−ySn_1+y) series. A series of tight-binding linear muffin-tin orbital calculations is conducted to understand overall electronic structures and chemical bonding among components. Magnetic susceptibility measurement indicates a ferromagnetic ordering of Eu atoms below 5 K for Eu_1.02(1)Ca_1.98InGe_2.87(1)Sn_1.13.     

Preparation and properties of poly(urethane acrylate) (PUA) and tetrapod ZnO whisker (TZnO‐W) composite films

Tetrapod zinc oxide whiskers (TZnO‐Ws) were successfully synthesized via a thermal oxidation method and confirmed using Fourier transform infrared spectroscopy, X‐ray diffraction and scanning electron microscopy. A series of poly(urethane acrylate) (PUA)/TZnO‐W composite films with various TZnO‐W contents were prepared via a UV curing method and their physical properties were investigated to understand their possible use as packaging materials. The morphological, thermal, mechanical, antibacterial and barrier properties of the PUA/TZnO‐W composite films were interpreted as a function of TZnO‐W content. The thermal stability, barrier properties and antibacterial properties of the composite films, which were strongly dependent upon their chemical and morphological structure, were enhanced as the TZnO‐W content increased. The oxygen transmission rate and water vapor transmission rate decreased from 614 to 161 cm³ m^?2 per day and 28.70 to 28.16 g m^?2 per day, respectively. However, the mechanical strength of the films decreased due to the low interfacial interaction and poor dispersion with high TZnO‐W loading. The enhanced barrier properties and good antibacterial properties of the PUA/TZnO‐W composite films indicate that these materials are potentially suitable for many packaging applications. However, further studies are needed to increase the compatibility of polymer matrix and filler. © 2012 Society of Chemical Industry     

Beneficial Effects of Melatonin Combined with Exercise on Endogenous Neural Stem/Progenitor Cells Proliferation after Spinal Cord Injury

Endogenous neural stem/progenitor cells (eNSPCs) proliferate and differentiate into neurons and glial cells after spinal cord injury (SCI). We have previously shown that melatonin (MT) plus exercise (Ex) had a synergistic effect on functional recovery after SCI. Thus, we hypothesized that combined therapy including melatonin and exercise might exert a beneficial effect on eNSPCs after SCI. Melatonin was administered twice a day and exercise was performed on a treadmill for 15 min, six days per week for 3 weeks after SCI. Immunohistochemistry and RT-PCR analysis were used to determine cell population for late response, in conjunction with histological examination and motor function test. There was marked improvement in hindlimb function in SCI+MT+Ex group at day 14 and 21 after injury, as documented by the reduced size of the spinal lesion and a higher density of dendritic spines and axons; such functional improvements were associated with increased numbers of BrdU-positive cells. Furthermore, MAP2 was increased in the injured thoracic segment, while GFAP was increased in the cervical segment, along with elevated numbers of BrdU-positive nestin-expressing eNSPCs in the SCI+MT+Ex group. The dendritic spine density was augmented markedly in SCI+MT and SCI+MT+Ex groups. These results suggest a synergistic effect of SCI+MT+Ex might create a microenvironment to facilitate proliferation of eNSPCs to effectively replace injured cells and to improve regeneration in SCI.     

Experimental evaluation and performance enhancement prediction of desiccant assisted separate sensible and latent cooling air-conditioning system

CO₂ and R410A desiccant wheel (DW)-assisted separate sensible and latent cooling (SSLC) air-conditioning systems were tested under the AHRI standard. At a 50 °C regeneration temperature, the coefficient of performance (COP) of the vapor compression cycles improved only 7% from the respective baseline systems for both refrigerants. This paper proposed the idea of applying divided condensers (or gas coolers) to the R410A (or CO₂) SSLC system to enhance its performance. It was found that the application of divided heat exchangers to the SSLC system provided sufficiently hot airflow for regenerating the desiccant wheel at both a reduced high side pressure (from 10.4 MPa to 9.7 MPa for CO₂, from 3.46 MPa to 3.45 MPa for R410A) and a reduced discharge temperature from the condenser (gas cooler) (4 K lower for both refrigerants). The COP improvement is 36% and 61% to R410A and CO₂ baseline systems, respectively.     

Characteristics and Functional Properties of Protein Isolates from Various Peanut (Arachis hypogaea L.) Cultivars

Protein isolates from 9 cultivars of peanut (Arachis hypogaea L.) were compared. Sephadex G-200 gel filtration and nondenaturing polyacrylamide gel electrophoresis (NPAGE) of the protein isolates showed very similar patterns of arachin and nonarachin fractions. The content of individual fractions was somewhat different among cultivars, possibly indicating genetic variability. Sodium dodecyl sulfate-PAGE (SDS-PAGE) showed that the protein isolates had extremely complex sub-unit compositions. The content of acidic amino acids of the protein isolates was 34–38%, basic was 15–17%. Differences in some functionalities such as solubility and emulsification activity were conspicuous among cultivars.