A smart process controller framework for Industry 4.0 settings

This paper presents a smart supervisory framework for a single process controller, designed for Industry 4.0 shop floors. This digitization of a full supervisory suite for a single process controller enables self-awareness, self-diagnosis, self-prognosis, and self-healing (by definition, these "self" elements are missing from other supervisory frameworks diagnosing numerous controllers in parallel). The proposed framework is aligned with the concept of a Cyber Physical System (CPS), since its implementation generates a rich cyber physical entity of the controlled process. This CPS entity can either be considered as the process digital twin, or can provide a solid basis for generating it. Finally, the framework includes the main characteristics of Industry 4.0, such as advanced use of Artificial Intelligence (AI) and big data analysis. The framework is based on four modules: (1) Control and Awareness module—performing both continuous process control and adjustments, as well as machine learning (ML) and statistical process control (SPC) for identifying abnormalities that require further diagnosis; (2) Process -diagnosis module—performing continual (recurrent) analysis of the process state and trends; (3) Prognosis and Healing module—performing prognosis and automated intervention via parameter changes, re-configurations, and automated maintenance; (4) External Interaction Platform—an interactive module for interfacing with experts, presenting them with the process analysis information and obtaining feedback from them as part of a learning process. Using an implementation showcase to illustrate the methodological framework’s applicability, we demonstrate its real-world potential. The proposed framework could serve as a guide for implementing smart process control and maintenance systems in Industry 4.0 shop floors. It could also provide a firm basis for comparison with future suggested frameworks. Future research directions could include pursuing improvements to the proposed process control framework and validating the framework by case studies of its implementation.

     

Cathepsin E expression by normal and premalignant cervical epithelium

We have investigated the expression of the aspartic proteinase cathepsin E and HLA-DR and the presence of HPV16 in normal squamous epithelium (n = 8) and low-grade (n = 21) and high-grade (n = 14) intraepithelial squamous lesions of the uterine cervix. Immunohistochemistry of cervical biopsies revealed that up-regulation of cathepsin E expression was related to increasing severity of the cervical intraepithelial neoplasia (CIN). Up-regulation of protein was associated with increased message as assessed by in situ hybridization. Langerhans cells and the majority of koilocytes did not express detectable cathepsin E levels. Although there was also an up-regulation of HLA-DR expression by cervical keratinocytes in cervical intraepithelial neoplasia lesions, as determined by immunohistochemistry, no significant correlation was found between HLA-DR and cathepsin E expression in these lesions; neither was expression of cathepsin E correlated to the presence of HPV16, detected by polymerase chain reaction. The expression of cathepsin E, an aspartic proteinase that is reported to play a role in antigen processing for presentation by class II major histocompatibility complex molecules, is associated with cellular dedifferentiation in cervical intraepithelial neoplasia.     

最快晶体管的频率接近太赫兹

Robert J.Mears是用于宽带互联网的铒掺杂光纤放大器(EDFA)的发明者。他在寻找将光器件和波导结合到硅中的方法时,发现了一个有趣的结果:一种特殊的硅超晶格结构可以加速某一个     

Organochlorine Contaminants of Wintering Ducks Foraging on Detroit River Sediments

Organochlorine analysis was performed on carcasses of 13 diving ducks from a 1981 wintering population that foraged on contaminated sediments in the lower Detroit River. Mean total PCB concentrations were 10 mg/kg for seven lesser scaups (Aythya affinis), 11 mg/kg for three greater scaups (A. marila), and 7.6 mg/kg for three goldeneyes (Bucephala clangula). Highest mean levels of other residues were measured for hexachlorobenzene (1.7 mg/kg) in goldeneyes, and transnonachlor (0.33 mg/kg) and 4,4’-DDE (1.3 mg/kg) in greater scaup. Quantitative analysis of 72 PCB congeners also was applied to water, seston, sediment, benthie oligochaetes, and carp from the same site. Principal congeners in most of the samples included some of the more toxic and persistent PCBs. Results of a multivariate analysis indicated that ratios of more conservative to less conservative PCBs did not vary significantly among ducks (α = .05), but differed from those in carp, oligochaetes, and sediment. For the February through March period of fat mobilization, concentrations of total PCB in lipid were inversely correlated with percent lipid (r = 0.76) in ducks. The percentage of conservative PCBs increased slightly. The distribution and partitioning of organochlorines, including toxic PCB congeners, varied considerably within this water column-sediment-fauna ecosystem. Estimates of toxic exposure based on total PCB values may be unreliable.     

Universal linear least squares prediction: upper and lower bounds

We consider the problem of sequential linear prediction of real-valued sequences under the square-error loss function. For this problem, a prediction algorithm has been demonstrated whose accumulated squared prediction error, for every bounded sequence, is asymptotically as small as the best fixed linear predictor for that sequence, taken from the class of all linear predictors of a given order p. The redundancy, or excess prediction error above that of the best predictor for that sequence, is upper-bounded by A/sup 2/P ln(n)/n, where n is the data length and the sequence is assumed to be bounded by some A. We provide an alternative proof of this result by connecting it with universal probability assignment. We then show that this predictor is optimal in a min-max sense, by deriving a corresponding lower bound, such that no sequential predictor can ever do better than a redundancy of A/sup 2/p ln(n)/n.     

Constructing inferences during narrative text comprehension.

Describes a constructionist theory that accounts for the knowledge-based inferences that are constructed when readers comprehend narrative text. Readers potentially generate a rich variety of inferences when they construct a referential situation model of what the text is about. The proposed constructionist theory specifies that some, but not all, of this information is constructed under most conditions of comprehension. The distinctive assumptions of the constructionist theory embrace a principle of search (or effort) after meaning. According to this principle, readers attempt to construct a meaning representation that addresses the reader's goals, that is coherent at both local and global levels, and that explains why actions, events, and states are mentioned in the text. This study reviews empirical evidence that addresses this theory and contrasts it with alternative theoretical frameworks. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Investigating onset, cessation, relapse, and recovery: Why you should, and how you can, use discrete-time survival analysis to examine event occurrence.

Illustrates how discrete-time survival analysis can address questions about onset, cessation, relapse, and recovery. Using data on the onset of suicide ideation and depression and relapse into cocaine use, the authors introduce key concepts underpinning the method, describe the action of the discrete-time hazard model, and discuss several types of main effects and interactions that can be included as predictors. Practical issues of data analysis and strategies for interpretation and presentation are discussed. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

The application of loss-free resistors in power processing circuits

Applications of loss-free elements with resistive characteristics in power processing systems are discussed. The synthesis of this kind of element is based on the control of a two port which has a transformer or gyrator matrix. Both of the controlled two ports can be realized by means of switched mode circuits. The loss-free resistor can be applied to the stabilization of unstable systems, for damping oscillatory waveforms, and balancing of power flow in AC-DC conversion systems. This kind of element has been applied to the stabilization of a gas laser system. It replaced a conventional resistive element which was applied for this purpose     

Effects of order of presentation on perceptions of the counselor.

Attempted to determine whether the order in which 2 counselors were presented on videotape would affect ratings of their performances. 70 participants (63 women and 7 men) randomly assigned to 2 groups viewed and rated counseling interviews conducted by C. Rogers and E. L. Shostrom. Groups differed only in the order of presentation of counselors. The resulting 2?×?2 split-plot factorial design had 1 between-Ss factor (order of presentation) and 1 within-S factor (counselor). A multivariate analysis of variance (MANOVA) yielded a statistically significant interaction, indicating that the order in which counselors were evaluated significantly affected the magnitude of ratings of their performance. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Area-efficient high-throughput MAP decoder architectures

Iterative decoders such as turbo decoders have become integral components of modern broadband communication systems because of their ability to provide substantial coding gains. A key computational kernel in iterative decoders is the maximum a posteriori probability (MAP) decoder. The MAP decoder is recursive and complex, which makes high-speed implementations extremely difficult to realize. In this paper, we present block-interleaved pipelining (BIP) as a new high-throughput technique for MAP decoders. An area-efficient symbol-based BIP MAP decoder architecture is proposed by combining BIP with the well-known look-ahead computation. These architectures are compared with conventional parallel architectures in terms of speed-up, memory and logic complexity, and area. Compared to the parallel architecture, the BIP architecture provides the same speed-up with a reduction in logic complexity by a factor of M, where M is the level of parallelism. The symbol-based architecture provides a speed-up in the range from 1 to 2 with a logic complexity that grows exponentially with M and a state metric storage requirement that is reduced by a factor of M as compared to a parallel architecture. The symbol-based BIP architecture provides speed-up in the range M to 2M with an exponentially higher logic complexity and a reduced memory complexity compared to a parallel architecture. These high-throughput architectures are synthesized in a 2.5-V 0.25-/spl mu/m CMOS standard cell library and post-layout simulations are conducted. For turbo decoder applications, we find that the BIP architecture provides a throughput gain of 1.96 at the cost of 63% area overhead. For turbo equalizer applications, the symbol-based BIP architecture enables us to achieve a throughput gain of 1.79 with an area savings of 25%.