Molecularly imprinted macroporous polymer monolithic layers for L-phenylalanine recognition in complex biological fluids

In present work, the development of macroporous monolithic layers bearing the artificial recognition sites toward L-phenylalanine has been carried out. The set of macroporous poly(2-aminoethyl methacrylate-co-2-hydroxyethyl methacrylate-co-ethylene glycol dimethacrylate) materials with average pore size ranged in 340–1200 nm was synthesized. The applicability of Hildebrand's and Hansen's theories for the prediction of polymer compatibility with porogenic solvents was evaluated. The dependences of average pore size on theoretically calculated parameters were plotted. The linear trend detected for Hansen's theory has indicated the high suitability of this approach to select appropriate porogens. The synthesized monolithic MIP layers were tested toward the ability to rebind phenylalanine-derivative in microarray format. The influence of such factors as average pore size of the material, the concentration of template molecule in polymerization mixture, interaction time of analyte with its imprinted sites on binding efficiency were studied. The developed materials demonstrated good analyte rebinding from buffer solution with recognition factors 2.5–3.4 depending on the MIP sample. The comparable rebinding efficiency was also detected when the analysis was carried using complex biological media. The selectivity of phenylalanine binding from the equimolar mixture of structural analogues was 81.9% for free amino acid and 91.2% for labeled one.     

Semipermeable dynamic membranes for ultrafiltration treatment of ground waters to remove radionuclides

The applicability of semipermeable dynamic membranes based on iron hydroxides and polyvinyl alcohol for ultrafiltration treatment of ground waters to remove radionuclides was studied. The retention of multiple-charged uranium ions and strontium is the most efficient, and that of cesium ion, the least efficient.     

Importance of scintigraphy in the evaluation of surgical treatment outcome in differentiated cancer of the thyroid gland

Experience of radionuclide investigation in 493 patients with differentiated cancer of thyroid gland is summarized. The consequences due to incorrect conducting of patients with cancer after the operation were adduced on distinct examples. The program for conducting and observation of patients with thyroid gland cancer after the operation conduction was proposed directed on the early diagnosis of recurrencies and metastases, determination of indications for radioiodine therapy.     

Synthesis and evaluation of N,N-dibutylundecenamide as new eco-friendly plasticizer for polyvinyl chloride

Journal of Materials Science - Tertiary fatty amide, namely N,N-dibutylundecenamide (DBUA), has been synthesized and evaluated as potential plasticizer for polyvinyl chloride (PVC). Homogeneous...     

Decontamination of liquid radioactive waste from transuranium elements and uranium by complexation with functionalized oligoethers, combined with ultrafiltration

Decontamination of liquid radioactive waste (LW) from transuranium elements (TUEs) and uranium by complexation with phosphorus-containing and guanidine phosphate oligoethers and by ultrafiltration was studied. The rejection coefficient of TUEs and U on these oligomers reaches 99.0–99.6% of the initial concentration.