全文获取类型
收费全文 | 52篇 |
免费 | 3篇 |
专业分类
化学工业 | 15篇 |
金属工艺 | 1篇 |
机械仪表 | 2篇 |
建筑科学 | 4篇 |
轻工业 | 5篇 |
无线电 | 2篇 |
一般工业技术 | 12篇 |
冶金工业 | 5篇 |
自动化技术 | 9篇 |
出版年
2023年 | 1篇 |
2021年 | 5篇 |
2020年 | 1篇 |
2019年 | 1篇 |
2018年 | 2篇 |
2016年 | 5篇 |
2015年 | 1篇 |
2014年 | 2篇 |
2013年 | 7篇 |
2012年 | 6篇 |
2011年 | 5篇 |
2010年 | 3篇 |
2009年 | 3篇 |
2008年 | 2篇 |
2007年 | 1篇 |
2006年 | 1篇 |
2003年 | 1篇 |
1998年 | 2篇 |
1997年 | 2篇 |
1996年 | 1篇 |
1993年 | 2篇 |
1991年 | 1篇 |
排序方式: 共有55条查询结果,搜索用时 31 毫秒
1.
Faustino Bisaccia Prashant Koshal Vittorio Abruzzese Maria Antonietta Castiglione Morelli Angela Ostuni 《International journal of molecular sciences》2021,22(6)
Pseudoxanthoma elasticum (PXE) is a complex autosomal recessive disease caused by mutations of ABCC6 transporter and characterized by ectopic mineralization of soft connective tissues. Compared to the other ABC transporters, very few studies are available to explain the structural components and working of a full ABCC6 transporter, which may provide some idea about its physiological role in humans. Some studies suggest that mutations of ABCC6 in the liver lead to a decrease in some circulating factor and indicate that PXE is a metabolic disease. It has been reported that ABCC6 mediates the efflux of ATP, which is hydrolyzed in PPi and AMP; in the extracellular milieu, PPi gives potent anti-mineralization effect, whereas AMP is hydrolyzed to Pi and adenosine which affects some cellular properties by modulating the purinergic pathway. Structural and functional studies have demonstrated that silencing or inhibition of ABCC6 with probenecid changed the expression of several genes and proteins such as NT5E and TNAP, as well as Lamin, and CDK1, which are involved in cell motility and cell cycle. Furthermore, a change in cytoskeleton rearrangement and decreased motility of HepG2 cells makes ABCC6 a potential target for anti-cancer therapy. Collectively, these findings suggested that ABCC6 transporter performs functions that modify both the external and internal compartments of the cells. 相似文献
2.
Claudio Paulo Faustino Camila Paiva Novaes Carlos Alberto M. Pinheiro Otávio A. Carpinteiro 《Artificial Intelligence Review》2014,41(2):287-300
Prediction models based on artificial intelligence techniques have been widely used in Time Series Forecasting in several areas. They are often fuzzy models or neural networks. This paper describes the development of neural and fuzzy models for forecasting time series of practical examples, and shows the comparisons of results between models, including the results of statistical modeling. The use of data clustering algorithms like Fuzzy C-Means is considered in fuzzy models. 相似文献
3.
This paper presents an approach for evaluating collaboration attributes in companies operating in industrial clusters. From the literature review, we identified governance, geographic proximity, and trust as the main collaboration attributes in industrial clusters. For each of them, there is a set of related sub-attributes that composed the evaluation model. For developing the model, we used the graph theoretic approach (GTA), a methodology for multi-attribute assessment that considers interdependencies among elements of a system to provide an overall evaluation. We applied the model to five companies of a furniture cluster. The results showed the model allows for systematizing relationship management because it highlights the collaboration attributes that need to be improved. Furthermore, the application of the model may contribute to encouraging companies to develop collaborative practices. 相似文献
4.
5.
The use of a sequential linear complementarity problem (SLCP) algorithm for finding a global minimum of bilinear programming problem (BLP) or a concave quadratic program (CQP) is examined. The algorithm consists of solving a sequence of linear complementarity problems (LCP). A branch-and-bound method is also considered in this study. This algorithm is based on the reformulation of a BLP into an LCP with a linear function to minimize. Computational experience with small and medium scale BLPs and CQPs indicates that the SLCP algorithm is quite efficient in finding a global minimum (or at least a solution that is quite near the optimum), but it is, in general, unable to establish that such a solution has been found. An algorithm to find a lower-bound for the BLP can overcome this drawback in some cases. Furthermore the SLCP algorithm is shown to be robust and compares favorably with the branch-and-bound method and another alternative technique. 相似文献
6.
Luciana Juncioni de Arauz Angela Faustino Jozala Gabriel Soares Pinheiro Priscila Gava Mazzola Adalberto Pessoa Júnior Thereza Christina Vessoni Penna 《Journal of chemical technology and biotechnology (Oxford, Oxfordshire : 1986)》2008,83(3):325-328
BACKGROUND: Nisin is a commercially available bacteriocin produced by Lactococcus lactis ATCC 11454 and used as a natural agent in the biopreservation of food. In the current investigation, milk whey, a byproduct from dairy industries was used as a fermentation substrate for the production of nisin. Lactococcus lactis ATCC 11454 was developed in a rotary shaker (30 °C/36 h/100 rpm) using two different media with milk whey (i) without filtration, pH 6.8, adjusted with NaOH 2 mol L?1 and without pH adjustment, both autoclaved at 121 °C for 30 min, and (ii) filtrated (1.20 µm and 0.22 µm membrane filter). These cultures were transferred five times using 5 mL aliquots of broth culture for every new volume of the respective media. RESULTS: The results showed that culture media composed of milk whey without filtration supplied L. lactis its adaptation needs better than filtrated milk whey. Nisin titers, in milk whey without filtration (pH adjusted), was 11120.13 mg L?1 in the second transfer, and up to 1628‐fold higher than the filtrated milk whey, 6.83 mg.L?1 obtained in the firstt transfer. CONCLUSIONS: Biological processing of milk byproducts (milk whey) can be considered a profitable alternative, generating high‐value bioproducts and contributing to decreasing river disposals by dairy industries. Copyright © 2008 Society of Chemical Industry 相似文献
7.
De Santo NG De Santo RM Perna AF Bisaccia C Pišot R Cirillo M 《Hemodialysis international. International Symposium on Home Hemodialysis》2011,15(2):178-182
Nowadays, there is a renewed interest in bone changes in experimental and clinical nephrology. However, the need for understanding the peculiarity of bone can be traced back to the 5th century BC, when Empedocles of Acragas put forward a theory of a world made of air, water, fire, and earth governed by love and hate. By observing the various body tissues, he strove to demonstrate that they consisted of 4 elements assembled with different mathematical ratios (logos). Blood is considered the most perfect tissue, because the ratio between elements is one. Bone is a very unusual tissue because it is made of 2 parts of earth, 2 parts of water, and 4 parts of fire. This kind of reasoning could be considered the first cry in the birth of quantitative chemistry. 相似文献
8.
Andrea Fasoli Alan Colli Faustino Martelli Simone Pisana Ping Heng Tan Andrea C. Ferrari 《Nano Research》2011,4(4):343-359
We present temperature and power dependent photoluminescence measurements on CdSe nanowires synthesized via vapor-phase with
and without the use of a metal catalyst. Nanowires produced without a catalyst can be optimized to yield higher quantum efficiency,
and narrower and spatially uniform emission, when compared to the catalyst-assisted ones. Emission at energies lower than
the band-edge is also found in both cases. By combining spatially-resolved photoluminescence and electron microscopy on the
same nanowires, we show that catalyst-free nanowires exhibit a low-energy peak with sharp phonon replica, whereas for catalyst-assisted
nanowires low-energy emission is linked to the presence of nanostructures with extended morphological defects.
相似文献
9.
Hlio Faustino Paloma Bernal Luis Castedo Fernando Lpez Jos L. Mascareas 《Advanced Synthesis \u0026amp; Catalysis》2012,354(9):1658-1664
3‐(Propa‐1,2‐dien‐1‐yl)oxazolidin‐2‐one works as an efficient two‐carbon partner in a variety of intermolecular gold‐catalyzed [2+2] cycloadditions to alkenes. The transformation represents a simple and practical entry to highly substituted cyclobutane derivatives and takes place with complete regio‐ and stereocontrol. 相似文献
10.
The use of FRP composites for the confinement of concrete has become an important aspect to consider on strengthening of concrete columns. It is important therefore that accurate modelling tools are available for the design of this system considering, not only the peak values of load and strain, but also the complete stress–strain behaviour. A wide group of authors have proposed several models specific for FRP-confined concrete based either on theoretical assumptions (analysis-oriented-models – AOMs) or on mathematical calibration from testing results (design-oriented-models – DOMs). This article carries out the implementation and analysis of nine existing models for circular concrete columns in view of axially tested reinforced concrete columns confined with CFRP with three different diameters: 150; 250 and 400 mm. The global shape of curves, peak compressive load, stress–strain relation, axial-to-lateral relation and dilation response were studied to conclude which models’ curves were closer to tests. Quantification of errors in face of the testing results was carried out for the most important parameters – ultimate load, strain and lateral stress – as well as for other curve parameters. Some models are accurate in predicting the peak load, though only few can accurately predict the load–strain and dilation behaviour. 相似文献