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排序方式: 共有1396条查询结果,搜索用时 15 毫秒
1.
We considered the magnetohydrodynamic (MHD) free convective flow of an incompressible electrically conducting viscous fluid past an infinite vertical permeable porous plate with a uniform transverse magnetic field, heat source and chemical reaction in a rotating frame taking Hall current effects into account. The momentum equations for the fluid flow during absorbent medium are controlled by the Brinkman model. Through the undisturbed state, both the plate and fluid are in a rigid body rotation by the uniform angular velocity perpendicular to an infinite vertical plate. The perpendicular surface is subject to the homogeneous invariable suction at a right angle to it and the heat on the surface varies about a non-zero unvarying average whereas the warmth of complimentary flow is invariable. The systematic solutions of the velocity, temperature, and concentration distributions are acquired systematically by utilizing the perturbation method. The velocity expressions consist of steady-state and fluctuating situations. It is revealed that the steady part of the velocity field has a three-layer characteristic while the oscillatory part of the fluid field exhibits a multi-layer characteristic. The influence of various governing flow parameters on the velocity, temperature, and concentration are analyzed graphically. We also discuss computational results for the skin friction, Nusselt number, and Sherwood number in the tabular forms. 相似文献
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3.
Jagadeesh Nagendra Manda Milica Markovic Prof. Ellen M. Zimmermann Prof. Shimon Ben-Shabat Prof. Arik Dahan Prof. Aaron Aponick 《ChemMedChem》2020,15(17):1639-1644
Novel phospholipid (PL)-cyclosporine conjugates were prepared and studied as potential prodrugs for inflammatory bowel disease (IBD). Our approach relies on phospholipase A2 (PLA2), which is overexpressed in the inflamed intestinal tissues, as the prodrug activator to potentially release cyclosporine at the site of inflammation. PL-cyclosporine prodrug conjugates with methylene linkers of various lengths between the sn-2 position of the PL and cyclosporine were synthesized and evaluated for in vitro activation. Surprisingly, despite previous work indicating that conjugates with six methylene linkers between the lipid and drug would suffer rapid enzymatic hydrolysis, with cyclosporine this was not observed. However, compounds with longer linkers (n=10, 12 methylene units) display complete release of the drug by PLA2-catalyzed hydrolysis, thus demonstrating the importance and profound impact of structural fine-tuning. This study represents a proof-of-concept for our hypothesis and a first step towards a truly targeted IBD treatment with cyclosporine that could be administered throughout the GI tract. 相似文献
4.
As the world moves toward more green and efficient means of modes of transport, electric vehicles are the most suitable and ideal choice to fulfill this requirement. Rapid developments in the field of battery technology are the main reason for their progress, but thermal management in such systems has been an area of concern for a long time. The work undertaken is to design and develop a battery management system (BMS) with a specific focus on the thermal behavior of the battery pack with varying vehicle loads as well as environmental conditions. To design an efficient BMS, one needs to model the battery behavior covering the thermal as well as electrical aspects of the battery. Apart from the battery model, a mathematical model of the electrical vehicle to mimic the various road load conditions for battery also needs to be modeled. Depending on the need for cooling based on battery behavior, the cooling circuit is modeled for the battery pack used. The entire study has been carried out using Dymola, a mathematical modeling software. 相似文献
5.
M. Sreedhar Babu Velpula V. Ramana G. Ravisankar C. S. K. Raju M. N. Bashir Sabir A. Shehzad 《亚洲传热研究》2020,49(8):4226-4245
In this investigation, the flow of an unsteady mixed convection boundary layer viscous nanofluid on a stretchable sheet is considered. The flow examination is affected by a magnetic field. The reason for the examination exhibited is to create models for nanomaterials that incorporate the Brownian movement and thermophoresis phenomena. The created nonlinear standard differential condition is illuminated numerically utilizing the Runge-Kutta-Gill technique and the start program. The different factors of speed, temperature, and concentration are reported and discussed. The examination shows that the speed, temperature, and concentration are lower in contrast with the consistent stream on account of an assisting flow, whereas the opposite situation is noticed in the opposing flow case. The effects of Brownian movement and thermophoresis in the concentration case are totally different. 相似文献
6.
Mohanalakshmi Sabapati Narahari N. Palei Ashok Kumar C.K. Ravindra Babu Molakpogu 《Drug development and industrial pharmacy》2019,45(4):577-586
The present study was aimed to develop Annona muricata fruit extract loaded solid lipid nanoparticles (SLNs) and explore its cytotoxic potential in vitro model of breast cancers. Extract loaded SLNs were successfully prepared by high-pressure homogenization followed by ultrasonication method and optimized using 23 full factorial design. The extract loaded SLNs were characterized using different parameters such as particle size (PS), % entrapment efficiency (EE), zeta potential (ZP) and % cumulative drug release (CDR). The SLNs formulation was optimized on the basis of software analysis with an overall desirability factor. The PS and %EE of the optimized formulation were found to be 134.8?nm and 83.26%, respectively. The optimized formulation showed a CDR of 79.83% up to 48?h. In vitro cytotoxicity efficacy of extract loaded SLNs was determined using MTT and Apoptosis assay and compared to that of a free extract. The SLNs showed a notable apoptotic effect and better efficacy to kill MCF7 cancer cells as compared to free extract. Thus, extract loaded SLNs could be an alternative dosage form which possibly controls therapeutic action with reducing side effect. 相似文献
7.
Jagadeesh Babu Sriramoju Murthy Muniyappa Navya Rani Marilingaiah Chetana Sabbanahalli Manjunath Shetty Ravi Mudike Chitrabanu C.P Prasanna D. Shivaramu Nagaraju G Kanchugarakoppal S. Rangappa Ananda Kumar C.S Dinesh Rangappa 《Ceramics International》2021,47(7):10314-10321
Application of brown titanium dioxide (TiO2-x) and its modified composite forms in the photocatalytic decomposition of organic pollutants in the environment is a promising way to provide solutions for environmental redemption. Herein, we report the synthesis of effective and stable TiO2-x nanoparticles with g-C3N4, RGO, and multiwalled carbon nanotubes (CNTs) using a simple hydrothermal method. Among all the as-synthesized samples, excellent photocatalytic degradation activity was observed for RGO-TiO2-x nanocomposite with high rate constants of 0.075 min?1, 0.083 min?1 and 0.093 min?1 for methylene blue, rhodamine-B, and rosebengal dyes under UV–Visible light irradiation, respectively. The altered bandgap (1.8 eV) and the large surface area of RGO-TiO2-x nanocomposite impacts on both absorption of visible light and efficiency of photogenerated charge electron (e?)/hole (h+) pair separation. This resulted in enhanced photocatalytic property of carbon-based TiO2-x nanocomposites. A systematic study on the influence of different carbon nanostructures on the photocatalytic activity of brown TiO2-x is carried out. 相似文献
8.
Mallikarjuna A. Kumar N. Suresh Babu T. Anil Ramesh S. Naidu K. Chandra Babu 《Journal of Inorganic and Organometallic Polymers and Materials》2021,31(12):4512-4522
Journal of Inorganic and Organometallic Polymers and Materials - (1-x) (Al0.2La0.8TiO3)?+?(x) (BiZnFeO3) (x?=?0.2–0.8) [ALTBZFO] nanocomposites were synthesized via... 相似文献
9.
Kamenan Koffi A. Jagadeesh Anooja Kre N’guessan Raymond Assanvo Edja Florentin Soman Suraj Unni K. N. Narayanan 《Journal of Materials Science: Materials in Electronics》2021,32(11):14207-14216
Journal of Materials Science: Materials in Electronics - We successfully fabricated dye sensitized solar cells (DSSCs) employing a quasi-solid state electrolyte based on pristine insulator natural... 相似文献
10.
Awdhesh Kumar Choudhary Bhardwaj Pandit G.L. Sivakumar Babu 《Geotextiles and Geomembranes》2019,47(2):203-216
The paper investigates the uplift performance of horizontal anchor plate in geocell reinforced sand through a series of model tests. It is noted that the unreinforced anchor plate undergoes a clear failure at a displacement of about 3% of its width, whereas with the provision of geocell and a layer of geotextile right below the geocell mattress significantly increases the uplift capacity by about 4.5 times higher than that of unreinforced sand and could sustain anchor displacement of more than 60%. Results indicates that the geocell mattress by virtue of its rigidity distributes the uplift load in the lateral directions to a larger area, thereby reducing the stress in the overlying soil mass and hence increases the performance of anchor plate system. The provision of the additional geotextile layer right below the geocell mattress is found to be very effective in increasing the stiffness as well as load carrying capacity of anchor plate system. The optimum size (i.e., width and length) of geocell mattress giving adequate load carrying capacity of anchor plate is found to be 5.4 times of anchor width (5.4B). The comparison of model tests results with 3D numerical analysis shows good agreement, indicating that the proposed model is able to capture the uplift load-displacement behaviour of geocell reinforced anchor plate system. 相似文献