原油混炼对润滑油黏度指数的影响

分析了不同原油及其混合油的性质,以及原油混炼对润滑油基础油生产运行和黏度指数的影响,考察了长庆、青海和牙哈3种原油在不同配比时的>360~500℃馏分段的润滑油基础油性能特点。结果表明,通过调整影响润滑油基础油黏度指数较高的青海和牙哈原油的掺混比例,控制常减压馏程宽度,采用深度溶剂精制及降低深度脱蜡工艺,可以提高润滑油基础油黏度指数,最终产品合格率由调整前的69.57%提高至调整后的86.84%。     

印刷业转型升级理论与实践研究探析

印刷业作为文化产业的主力军近年来发展放缓,转型升级成为当务之急。结合印刷业发展实际,从核心竞争力和动态能力、全球价值链(GVC)和产业集群等方面入手,立足理论方法和实践创新两个方面,对印刷业转型升级问题做了分析思考。指出国内印刷业要转型升级,需要提高核心竞争力,关注产业价值链,重视产业集群。     

硼替佐米对胃癌细胞的抗肿瘤作用及其机制

目的: 观察硼替佐米对胃癌细胞的抗肿瘤作用,并探讨其相关的作用机制。方法: MTT生长抑制实验检测硼替佐米对胃癌SGC-7901细胞的细胞毒作用;PI和Annexin V-FITC双染流式细胞仪检测细胞凋亡情况;Western blot实验检测蛋白的表达变化。结果: 硼替佐米对胃癌SGC-7901细胞的IC₅₀值为(54.6±4.1) nmol/L。0、50、100 nmol/L 硼替佐米作用于SGC-7901细胞 48 h 后,细胞的凋亡率分别为(1.8±0.7)%、(26.5±4.6)%、(41.7±5.8)%,各组之间具有统计学差异(P<0.01)。50和 100 nmol/L 的硼替佐米作用SGC-7901细胞 48 h 后,细胞出现了Parp和caspase-3蛋白的裂解带。50和 100 nmol/L 的硼替佐米作用SGC-7901细胞 48 h 后,细胞Bmi-1蛋白的表达出现了显著的降低。结论: 硼替佐米对胃癌SGC-7901细胞具有显著的抗肿瘤活性,下调Bmi-1蛋白可能是其诱Anti-inflammatory effects of carboxyamidotriazole on carrageenan-induced acute inflammationZHU Lei, LI Juan, WU Dan-wei, YU Xiao-li, GUO Lei, YE Cai-ying, ZHANG De-changDepartment of Pharmacology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences & School of Basic Medicine, Peking Union Medical College, Beijing 100005, ChinaABSTRACT AIM: To investigate the preventive effects of carboxyamidotriazole (CAI) in rat model of carrageenan-induced paw acute inflammation and its mechanisms.METHODS: The paw acute inflammation in rats was induced by carrageenan. The paw swelling was measured, and myeloperoxidase (MPO), NO, PGE₂, TNF-α, IL-1β, cytokine-induced neutrophil chemoattractant-1 (CNCI-1) and iNOS in the paw tissues were determined.RESULTS:CAI attenuated the carrageenan-induced paw swelling. CAI decreased the contents of MPO, NO, PGE₂, TNF-α, IL-1β and CNCI-1 in the inflamed paw tissues. Also, the protein expression of iNOS was reduced by CAI.CONCLUSION: CAI has anti-inflammatory effects against carrageenan-induced acute inflammation by decreasing the inflammatory mediators and the neutrophils infiltration.KEY WORDS Carboxyamidotriazole; Acute inflammation; Carrageenan; Myeloperoxidase; Inflammatory mediators本文编辑:储冀汝导胃癌细胞凋亡的主要作用机制。     

安徽宣城天然斜发沸石深度处理氨氮废水研究

选用对氨氯有较强选择性和吸附性的安徽宣城天然斜发沸石为吸附材料,通过静态、动态和再生吸附实验,系统考察了进水氨氮浓度、pH值、沸石用量、温度、沸石粒径、振荡时间、滤速和水质对氨氤去除率的影响.静态实验结果表明,初始浓度为10mg/L、pH值为7～9之间、粒径为20～40目,静态吸附容量1.6mmol NH4/g.动态实验结果表明,滤速为2m/h、停留时间为30min,出水氨氮浓度达2mg/L以下,每g沸石产水量为0.62L.再生实验结果表明,用500mL浓度为5g/L NaCl溶液作为再生剂,再生时间为1h,一次再生恢复率较好.实验结果为天然沸石深度处理氨氮废水技术的应用提供了参考依据.