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排序方式: 共有2158条查询结果,搜索用时 244 毫秒
1.
Lingfeng Zhou Zhipeng Zeng Michael P. Brady Donovan N. Leonard Harry M. Meyer Yukinori Yamamoto Wenyuan Li Greg Collins Xingbo Liu 《International Journal of Hydrogen Energy》2021,46(41):21619-21633
The chromium (Cr) evaporation behavior of several different types of iron (Fe)-based AFA alloys and benchmark Cr2O3-forming Fe-based 310 and Ni-based 625 alloys was investigated for 500 h exposures at 800 °C to 900 °C in air with 10% H2O. The Cr evaporation rates from alumina-forming austenitic (AFA) alloys were ~5 to 35 times lower than that of the Cr2O3-forming alloys depending on alloy and temperature. The Cr evaporation behavior was correlated with extensive characterization of the chemistry and microstructure of the oxide scales, which also revealed a degree of quartz tube Si contamination during the test. Long-term oxidation kinetics were also assessed at 800 to 1000 °C for up to 10,000 h in air with 10% H2O to provide further guidance for SOFC BOP component alloy selection. 相似文献
2.
Dr. Omer K. Rasheed Cassandra Buhl Dr. Jay T. Evans Dr. Kendal T. Ryter 《ChemMedChem》2021,16(8):1246-1251
Mincle agonists have been shown to induce inflammatory cytokine production, such as tumor necrosis factor-alpha (TNF) and promote the development of a Th1/Th17 immune response that might be crucial to development of effective vaccination against pathogens such as Mycobacterium tuberculosis. As an expansion of our previous work, a library of 6,6′-amide and sulfonamide α,α-d -trehalose compounds with various substituents on the aromatic ring was synthesized efficiently in good to excellent yields. These compounds were evaluated for their ability to activate the human C-type lectin receptor Mincle by the induction of cytokines from human peripheral blood mononuclear cells. A preliminary structure–activity relationship (SAR) of these novel trehalose diamides and sulfonamides revealed that aryl amide-linked trehalose compounds demonstrated improved activity and relatively high potency cytokine production compared to the Mincle ligand trehalose dibehenate adjuvant (TDB) and the natural ligand trehalose dimycolate (TDM) inducing dose-dependent and human-Mincle-specific stimulation in a HEK reporter cell line. 相似文献
3.
Anh K. Lam Hannah Panlilio Jennifer Pusavat Cassandra L. Wouters Erika L. Moen Prof. Robert E. Brennan Prof. Charles V. Rice 《ChemMedChem》2020,15(15):1421-1428
Infections from antibiotic-resistant Staphylococcus aureus and Pseudomonas aeruginosa are a serious threat because reduced antibiotic efficacy complicates treatment decisions and prolongs the disease state in many patients. To expand the arsenal of treatments against antimicrobial-resistant (AMR) pathogens, 600-Da branched polyethylenimine (BPEI) can overcome antibiotic resistance mechanisms and potentiate β-lactam antibiotics against Gram-positive bacteria. BPEI binds cell-wall teichoic acids and disables resistance factors from penicillin binding proteins PBP2a and PBP4. This study describes a new mechanism of action for BPEI potentiation of antibiotics generally regarded as agents effective against Gram-positive pathogens but not Gram-negative bacteria. 600-Da BPEI is able to reduce the barriers to drug influx and facilitate the uptake of a non-β-lactam co-drug, erythromycin, which targets the intracellular machinery. Also, BPEI can suppress production of the cytokine interleukin IL-8 by human epithelial keratinocytes. This enables BPEI to function as a broad-spectrum antibiotic potentiator, and expands the opportunities to improve drug design, antibiotic development, and therapeutic approaches against pathogenic bacteria, especially for wound care. 相似文献
4.
Bismark Sarkodie Collins Acheampong Benjamin Asinyo Xun Zhang Benjamin Tawiah 《Color research and application》2019,44(3):396-410
Novel treatments of pigments with inorganic materials have tremendous industrial and commercial prospects. Specific treatment of pigment has a marked effect on its behavior during application. The treatment allows a broad modification of the surface characteristics of pigment particles which leads to improved functionalities. Surface modification of pigments is achieved via coating, polymerization with modifying reagent, treatment with derivatives or polymers, which alter either the optical, conductivity or dispersibility during processing and application. These and many other distinguishing factors that affect the characteristics of pigments such as the class, crystal structure, particle morphology, particle size, hiding power, pigment volume concentration, surface character, and surface treatment have been reviewed. Various organic pigments such as those from fungus and bacteria, and the various families of pigment types such as metallic pigment, light interference, and diffractive pigments which presents decorative quality such as leafing, nonleafing, pearlscent, and Fabry‐Perot effects on substrates have also been reviewed in addition to those from inorganic sources with emphasis on the structure and physiochemical modifications using metal and nonmetal Ions. 相似文献
5.
6.
Sharma Nitin Kumar Kannan Rangasayee Li Leijun Anderson Neil Rashid Muhammad Collins Laurie Poplawsky Jonathan D. Unocic Raymond 《Metallurgical and Materials Transactions A》2021,52(9):3788-3798
Metallurgical and Materials Transactions A - The bondline of electric-resistance-welded (ERW) linepipe steel, often etched white (i.e., ferrite) in optical microscopy, is generally believed to be... 相似文献
7.
Ryan M. Williams Cassandra L. Crihfield Srikanth Gattu Lisa A. Holland Letha J. Sooter 《International journal of molecular sciences》2014,15(8):14332-14347
Widespread use of the chlorotriazine herbicide, atrazine, has led to serious environmental and human health consequences. Current methods of detecting atrazine contamination are neither rapid nor cost-effective. In this work, atrazine-specific single-stranded DNA (ssDNA) molecular recognition elements (MRE) were isolated. We utilized a stringent Systematic Evolution of Ligands by Exponential Enrichment (SELEX) methodology that placed the greatest emphasis on what the MRE should not bind to. After twelve rounds of SELEX, an atrazine-specific MRE with high affinity was obtained. The equilibrium dissociation constant (Kd) of the ssDNA sequence is 0.62 ± 0.21 nM. It also has significant selectivity for atrazine over atrazine metabolites and other pesticides found in environmentally similar locations and concentrations. Furthermore, we have detected environmentally relevant atrazine concentrations in river water using this MRE. The strong affinity and selectivity of the selected atrazine-specific ssDNA validated the stringent SELEX methodology and identified a MRE that will be useful for rapid atrazine detection in environmental samples. 相似文献
8.
A key issue confronting our newer suburbs is the stance they should take towards efforts at regional cooperation and coordination of major policy areas. This article analyzes the preferences on this issue held by residents in a rapid growth suburb in the St. Louis metropolitan area. Through factor analysis, four identifiable dimensions of regionalist preferences were obtained from questionnaire responses--administrative cooperation, land-use cooperation, mass transit cooperation, and regional basic services cooperation. Correlational analyses between these dimensions of regionalist preferences and selected community status characteristics, social situation characteristics, and local political participation status of respondents reveal no systematic covariation. Thus municipal policies which influence the population mix within a community with respect to the life situation characteristics measured in this study are not likely to be useful instruments for influencing the preferences, pro or con, of the community towards regionalist policies. Further, local political participants are found to be representative of the larger community's regionalist policy preferences. 相似文献
9.
John H. Collins Seong-Hoon Yoon Deepak Musale Jian Feng Kong Jeroen Koppes Suma Sundararajan Shih-Perng Tsai G. Anders Hallsby Philippe Cachia & Karen Kronoveter 《Water and Environment Journal》2006,20(1):43-47
Recently developed polymeric membrane performance enhancer product, MPE50, was tested in various pilot‐ and full‐scale membrane bioreactors (MBRs). The Initial MPE50 dosage was determined by visual jar tests and by using various bench‐top filtration tests. Different amounts of MPE50 were dosed, and the particle size and supernatant clarity of the mixed liquor were monitored visually. Bench‐top filtration tests were also conducted. A 50% higher MPE50 dosage is recommended to be added to the pilot/full‐scale bioreactors because, based on experience, some of the soluble microbial products in the mixed liquor do not completely react with polymer during the relatively short bench‐test mixing time interval. With the addition of 400 mg/L MPE50 to a pilot MBR, the design flow was increased twofold without any significant transmembrane pressure (TMP) increase for 1 day. The control TMP surged within a few hours without MPE50. Long‐term field trials in a full‐scale plant also showed a substantial flux increase. In addition to flux enhancement, MPE50 helped to remove foam from the bioreactors and improved plant aesthetics, safety and general operating performance. 相似文献
10.
Review 总被引:2,自引:0,他引:2
Paul Rodaway Peter Howard B. N. K. Davis Robert Lawson-Peebles Nick Robinson Michael Collins Susan Ford 《Landscape Research》1990,15(2):18-32
THE EXPERIENCE OF NATURE: A PSYCHOLOGICAL PERSPECTIVE by Rachel Kaplan & Stephen Kaplan, Cambridge University Press, 1989, 337pp, £10.95 (p/b), 0-521-34939-7.
THE ECOLOGY OF URBAN HABITATS by 0. L. Gilbert, Chapman & Hall, London, 1989, 369pp, 0-412-28270-4, £35.00.
DIRECTORY FOR THE ENVIRONMENT: ORGANISATIONS IN BRITAIN AND IRELAND 1986-7, Michael J. C. Barker, ed., London: Routledge & Kegan Paul, 1986. Second edition, pp. xviii + 278, £18.99, PB, ISBN 0-7102-0961-4.
THE URBAN ENVIRONMENT: A SOURCEBOOK FOR THE 1990s, Gerald Dawe, ed., Birmingham: Centre for Urban Ecology, 1990, pp. 636, £55.00, PB, ISBN 0-907272-07-X.
PLANTS IN THE LANDSCAPE (2nd Edn.), by Philip L. Carpenter and Theodore D. Walker, W. H. Freeman, New York and Oxford, 1990, 401 pp., ISBN 0-7167-1808-1, £29.95 HB.
SPORTS GEOGRAPHY by John Bale, E. & F. N. Spon, 1989, 0-419-14390-4, £16.95 PB.
THE POLITICS OF PARK DESIGN: A HISTORY OF URBAN PARKS IN AMERICA by Galen Cranz, ISBN 0 262 53084 8, 347pp, London: M.I.T. Press, 1989, £11.25, P.B. 相似文献
THE ECOLOGY OF URBAN HABITATS by 0. L. Gilbert, Chapman & Hall, London, 1989, 369pp, 0-412-28270-4, £35.00.
DIRECTORY FOR THE ENVIRONMENT: ORGANISATIONS IN BRITAIN AND IRELAND 1986-7, Michael J. C. Barker, ed., London: Routledge & Kegan Paul, 1986. Second edition, pp. xviii + 278, £18.99, PB, ISBN 0-7102-0961-4.
THE URBAN ENVIRONMENT: A SOURCEBOOK FOR THE 1990s, Gerald Dawe, ed., Birmingham: Centre for Urban Ecology, 1990, pp. 636, £55.00, PB, ISBN 0-907272-07-X.
PLANTS IN THE LANDSCAPE (2nd Edn.), by Philip L. Carpenter and Theodore D. Walker, W. H. Freeman, New York and Oxford, 1990, 401 pp., ISBN 0-7167-1808-1, £29.95 HB.
SPORTS GEOGRAPHY by John Bale, E. & F. N. Spon, 1989, 0-419-14390-4, £16.95 PB.
THE POLITICS OF PARK DESIGN: A HISTORY OF URBAN PARKS IN AMERICA by Galen Cranz, ISBN 0 262 53084 8, 347pp, London: M.I.T. Press, 1989, £11.25, P.B. 相似文献