Effect of propolis phenolic compounds on free fatty acid receptor 4 activation

Food Science and Biotechnology - Propolis is known to have multiple biological and pharmacological properties including the regulation of energy homeostasis. Although phenolic compounds are...     

Enhancement of lipid productivity by ethyl methane sulfonate-mediated random mutagenesis and proteomic analysis in Chlamydomonas reinhardtii

Microalgae-derived biomass has been considered as the most promising candidate for next generation biofuel due to its sustainability and biodegradability. In this study, microalgal strain Chlamydmonas reinhardtii was randomly mutagenized by using a chemical mutagen, ethyl methane sulfonate (EMS) to create mutants showing enhanced lipid production. We identified three random mutants that displayed high lipid production in the screening using Nile red staining. Among those, mutant #128 was selected as candidate for further studies. Our flow cytometry and confocal microscopy analysis revealed that mutant #128 contains larger and more abundant lipid bodies than that of wild-type. Moreover, mutant #128 showed 1.4-fold increased fatty acid methyl ester (FAME) content compared to wild-type under nitrogen depleted condition. In addition, mutant #128 grew faster and accumulated more biomass, resulting in high lipid production. 2D gel electrophoresis and MALDI-TOF analysis used for gene targeting revealed that β-subunit of mitochondrial ATP Synthase and two-component response regulator PilR may be involved in enhanced characteristics of mutant #128. These results show the possibilities of EMS mediated random mutagenesis in generation of mutants to produce high amount of lipid as well as further study for molecular mechanism of mutants.     

Prediction of plasma etch process by using actinometry-based optical emission spectroscopy data and neural network

Optical emission spectroscopy (OES) data were used to construct neural network models of plasma etch process. According to a statistical experiment, actinomeric OES data were collected from the etching of oxide thin films in a CHF₃–CF₄ magnetically enhanced reactive ion etching system. The etch responses modeled include an etch rate, a profile angle, and an etch rate-nonuniformity. Principal component analysis was applied to reduce the dimensionality of OES data. Three data variances adopted are 98, 99, and 100%. For each data variance, backpropagation neural network models were constructed. The training factors optimized by genetic algorithm include the training tolerance, magnitude of initial weight distribution, number of hidden neurons, and two gradients of activation functions in the hidden and output layers. The presented models demonstrated much improved predictions over the previous ones. The improvements were 43, 61, and 17% for the etch rate, profile angle, and etch rate-nonuniformity models, respectively.     

建设项目的职业安全卫生设计

建设项目职业安全卫生是设计工作重要的一环。在各设计阶段都应有“安全卫生”的内容，并把安全卫生设计包括在项目中，做到职业安全卫生和建设项目的“三同时”，才能保证石油化工企业的安全生产。     

Maximum production of methanol in a pilot-scale process

Mathematical models for both bench- and pilot-scale methanol synthesis reactors were developed by estimating the overall heat transfer coefficients due to different heat transfer characteristics, while the effectiveness factor was fixed because the same catalysts were used in both reactors. The overall heat transfer coefficient of a pilot-scale reactor was approximately twice that of a bench-scale reactor, while the estimate from the correlation reported for the heat transfer coefficient was 1.8-times higher, indicating that the values determined in the present study are effective. The model showed that the maximum methanol production rate of approximately 16 tons per day was achievable with peak temperature maintained below 250 °C in the open-loop case. Meanwhile, when the recycle was used to prevent the loss of unreacted gas, peak temperature and production rate decreased due to low CO and CO₂ fraction in the recycled stream at the same space velocity as the open-loop operation. Further analysis showed that, since the reaction was in the kinetic regime, the production rate could be maximized up to 18.7 tons per day by increasing the feed flowrate and inlet temperature despite thermodynamically exothermic reaction.     

实时多任务操作系统响应性能预估和测试

本文给出了作者开发的一个单处理机实时多任务操作系统的响应性能（响应时间，同步时间）的实验结果和／或估算。与国外同期文献发表的数据相比，指标先进。     

Zn2+-imprinted porous polymer beads: Synthesis,structure, and selective adsorption behavior for template ion

Zn²⁺-imprinted polymer was synthesized in porous spherical forms via a self-assembled complex between 2,2′-bipyridyl/4-vinylpyridine complexant/functional monomer and Zn²⁺ template ion. Diameters of particles ranged from 250 to 550 μm to enlarge the surface area and thus enhance the adsorption capacity. The presence/absence of the template ion in the preparation of the imprinted polymer was confirmed by EDX spectroscopy, and the physical structure of the particles was investigated using ESEM and BET analysis. The particle and the pore size were controlled by the cross-linker/monomer feed ratio. The adsorption capacity of the imprinted polymers was 210.61 μmol g^?1 for Zn²⁺, while those for Cu²⁺, Ni²⁺, and Pb²⁺, were 37.92 μmol g^?1, 33.02 μmol g^?1, and 9.70 μmol g^?1, respectively. This big discrepancy of the adsorption capacities illustrates the excellent separation selectivity of the imprinted polymers. The adsorption capacity decreased significantly at pH below 4.5, as the polymers are easily protonated. The imprinted particles lost only 10 % of their adsorption ability after 10 repeated uses.     

储能在能源安全中的作用

世界各国在积极发展可再生能源,而很大部分可再生能源用于发电.因此“能源安全”的范畴与重心将从20世纪的以石油安全为主逐步转向21世纪的以电力安全为主.确保安全、高质量供电,同时维持电力供需平衡是电力系统面临的持续挑战.发展新能源电力为常规电力机组的变负荷能力提出新的挑战:要求电力机组具备更快的变负荷调节能力;电力机组变负荷目标的不确定性增大;电力机组负荷调节范围更大.在电力系统中采用集成储能模块是解决电力系统变负荷和新能源电力接人产生问题的有效措施.储能总的作用是实现新能源电力上网、保持电网高效安全运行和电力供需平衡.储能系统的具体功能有三种:提高电能质量、提供桥接电能、能量管理.电力储能技术有抽水蓄能技术、压缩空气储能技术、超导储能技术、超级电容器储能技术、电化学储能技术、复合储能技术.对我国发展储能产业提出以下建议:从宏观战略层面制定储能发展规划;出台利于储能技术产业化的激励政策与机制;发布储能相关技术标准和管理规范,建立储能装置回收管理机制;加强储能技术研发与示范;建立储能产业链,降低成本;探索优化商业运营模式,加快储能技术的市场化步伐.     

Critical Factors to Understanding the Electrochemical Performance of All-Solid-State Batteries: Solid Interfaces and Non-Zero Lattice Strain

All-solid-state lithium batteries have been developed to secure safety by substituting a flammable liquid electrolyte with a non-flammable solid electrolyte. However, owing to the nature of solids, interfacial issues between cathode materials and solid electrolytes, including chemical incompatibility, electrochemo-mechanical behavior, and physical contact, pose significant challenges for commercialization. Herein, critical factors for understanding the performance of all-solid-state batteries in terms of solid interfaces and non-zero lattice strains are identified through a strategic approach. The initial battery capacity can be increased via surface coating and electrode-fabrication methods; however, the increased lattice strain causes significant stress to the solid interface, which degrades the battery cycle life. However, this seesaw effect can be alleviated using a more compacted electrode microstructure between the solid electrolyte and oxide cathode materials. The compact solid interfaces contribute to low charge-transfer resistance and a homogeneous reaction between particles, thereby leading to improved electrochemical performance. These findings demonstrate, for the first time, a correlation between the uniformity of the electrode microstructure and electrochemical performance through the investigation of the reaction homogeneity among particles. Additionally, this study furthers the understanding of the relationship between electrochemical performance, non-zero lattice strain, and solid interfaces.