Application of HEC-HMS Model for Evaluation of Rainwater Harvesting Potential in a Semi-arid City

Water Resources Management - With many countries facing water scarcity and the demand for water ever-increasing, more people are turning to rainwater harvesting (RWH) as a feasible way of...     

A tutorial on biomedical process control

This paper presents a tutorial on five typical applications within the area of biomedical process control. The specific applications discussed include: control of insulin administration for treating diabetes mellitus, dynamic modeling for anti-cancer chemotherapy regimen design, modeling and control of drug infusion in critical care, structured treatment interruptions: a control mathematical approach to AIDS protocol design, and dynamic modeling and control of the anticoagulant drug heparin. The objective of the tutorial is to illustrate the rich and important set of problems within the biomedical area that process control engineers can contribute to solving. Solution to these problems can have a significant medical as well as economic impact.     

When to initiate HIV therapy: a control theoretic approach

This paper shows an application of control theory to human immunodeficiency virus (HIV)/AIDS models. Minimum singular value decomposition is applied to HIV/AIDS models to measure the extent to which the different stages in the progression of HIV/AIDS disease are controllable and, consequently, when best to initiate therapy such that the general objectives of therapy are satisfied. Simulations will be used to demonstrate the effect of treatment at various stages. Comparisons will be made between mono-class and combination therapies and between when therapy is initiated at the acute infection, asymptomatic and the advanced stages.