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神经记录用硅基多通道微电极探针的设计与制造 总被引:2,自引:0,他引:2
为了从中枢神经系统记录电信号,半导体加工技术已经被用于微电极探针的制造.介绍了一种硅基探针的设计和制造工艺流程.我们已经制造出15 μm厚,3 mm长,100μm宽的记录用探针,每根探针含有7个记录点,间隔120 μm.在制造过程中使用微机械系统(MEMS)工艺中常用的硅表面微加工工艺:等离子增强化学气相淀积(PECVD),感应耦合等离子刻蚀(ICP)以及硅的各向异性刻蚀等.测试结果给出了探针的强度和阻抗特性. 相似文献
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An implantable optrode composed of fiber and multi-channel flexible thin-film electrode is developed. The flexible recording electrode is made from polyimide and is wrapped around the optical fiber. The front end of the fiber is tapered by wet etching. With the tapered shape, the light can leak from the sidewall of the fiber, and the tapered tip makes it easy to be implanted. The flexible electrode is attached with its recording sites aligning to the tapered part on the fiber. With this method, the fiber acts as an optical waveguide, as well as a support probe for flexible thin-film electrode. This novel device simplifies the fabrication process and decreases the size of the optrode. The device works well in vivo and the optical caused spike can be recorded with signal-to-noise ratio of 6:1. 相似文献
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:以体硅为衬底,采用微机械加工技术(MEMS)制作了七通道的可植入到脑皮层的微探针,用于记录神经电信号.从生物相容性、减小植入损伤、工艺制作难度等方面考虑,制作了以二氧化硅/硅(SiO2/Si)为主体的微探针,并详述了其具体制作工艺流程.扫描电镜(SEM)照片显示微探针针长3 mm、针宽100 μm、针厚约为20 μm,各个记录点直径10 μm、间距120μm,实现了各通道之间良好的信号隔离.微探针距离针尖1 mm范围内的针宽以一定弧度由100 μm逐渐变窄,同时针尖锥角为6°,此种结构有利于减小植入时对脑组织的损伤.通过体外测试得到,当频率由10 kHz增加到10 MHz时,微电极各个通道阻抗由150.5 kΩ降低到6.0 kΩ. 相似文献
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