全文获取类型
收费全文 | 147篇 |
免费 | 4篇 |
专业分类
综合类 | 2篇 |
化学工业 | 33篇 |
金属工艺 | 2篇 |
机械仪表 | 1篇 |
建筑科学 | 12篇 |
矿业工程 | 3篇 |
能源动力 | 5篇 |
轻工业 | 8篇 |
水利工程 | 6篇 |
无线电 | 17篇 |
一般工业技术 | 20篇 |
冶金工业 | 6篇 |
自动化技术 | 36篇 |
出版年
2021年 | 2篇 |
2020年 | 2篇 |
2017年 | 4篇 |
2016年 | 4篇 |
2015年 | 4篇 |
2014年 | 10篇 |
2013年 | 12篇 |
2012年 | 13篇 |
2011年 | 8篇 |
2010年 | 11篇 |
2009年 | 4篇 |
2008年 | 12篇 |
2007年 | 6篇 |
2006年 | 12篇 |
2005年 | 6篇 |
2004年 | 7篇 |
2003年 | 3篇 |
2002年 | 3篇 |
2001年 | 3篇 |
2000年 | 2篇 |
1998年 | 2篇 |
1996年 | 2篇 |
1994年 | 3篇 |
1991年 | 1篇 |
1987年 | 4篇 |
1986年 | 1篇 |
1985年 | 2篇 |
1984年 | 1篇 |
1983年 | 1篇 |
1982年 | 1篇 |
1981年 | 1篇 |
1979年 | 1篇 |
1934年 | 3篇 |
排序方式: 共有151条查询结果,搜索用时 31 毫秒
1.
2.
Sebastian Granitzer Raimund Widhalm Martin Forsthuber Isabella Ellinger Gernot Desoye Markus Hengstschlger Harald Zeisler Hans Salzer Claudia Gundacker 《International journal of molecular sciences》2021,22(4)
The placental barrier can protect the fetus from contact with harmful substances. The potent neurotoxin methylmercury (MeHg), however, is very efficiently transported across the placenta. Our previous data suggested that L-type amino acid transporter (LAT)1 is involved in placental MeHg uptake, accepting MeHg-L-cysteine conjugates as substrate due to structural similarity to methionine. The aim of the present study was to investigate the antioxidant defense of placental cells to MeHg exposure and the role of LAT1 in this response. When trophoblast-derived HTR-8/SVneo cells were LAT1 depleted by siRNA-mediated knockdown, they accumulated less MeHg. However, they were more susceptible to MeHg-induced toxicity. This was evidenced in decreased cell viability at a usually noncytotoxic concentration of 0.03 µM MeHg (~6 µg/L). Treatment with ≥0.3 µM MeHg increased cytotoxicity, apoptosis rate, and oxidative stress of HTR-8/SVneo cells. These effects were enhanced under LAT1 knockdown. Reduced cell number was seen when MeHg-exposed cells were cultured in medium low in cysteine, a constituent of the tripeptide glutathione (GSH). Because LAT1-deficient HTR-8/SVneo cells have lower GSH levels than control cells (independent of MeHg treatment), we conclude that LAT1 is essential for de novo synthesis of GSH, required to counteract oxidative stress. Genetic predisposition to decreased LAT1 function combined with MeHg exposure could increase the risk of placental damage. 相似文献
3.
Sandra Schlögl Marie-Luise Trutschel Walter Chassé Ilse Letofsky-Papst Raimund Schaller Armin Holzner Gisbert Riess Wolfgang Kern Kay Saalwächter 《Polymer》2014
The photo-vulcanization with versatile thiol-ene chemistry represents an innovative approach to crosslink diene-rubber materials both in latex and in solid film state. In this work, the structure of elastomer-based thiol-ene networks and the morphology after film formation are studied in detail using electron microscopic techniques, atomic force microscopy and multiple-quantum solid-state NMR spectroscopy. Additionally, film formation properties and corresponding macroscopic properties of photo-vulcanized natural rubber (NR) latex and its synthetic counterpart, isoprene rubber (IR) latex, are determined in dependence on the curing procedure (pre- and post-vulcanization). The results reveal that thiol-ene cured elastomers comprise homogenously distributed crosslinks with a low amount of short chain defects. Whilst photochemically pre-cured NR latex particles provide coherent films, the film formation and mechanical properties of IR are strongly governed by the crosslink density of the latex particles. In film state, photo-vulcanization promotes narrow crosslink distributions and excellent tensile properties of both NR and IR. 相似文献
4.
Georg Raimund Pirrung Maarten Paul van der Laan Nstor Ramos‐García Alexander Raul Meyer Forsting 《风能》2020,23(4):1154-1163
The loading of a wind turbine decreases towards the blade tip because of the velocities induced by the tip vortex. This tip loss effect has to be taken into account when performing actuator disc simulations, where the single blades of the turbine are not modeled. A widely used method applies a factor on the axial and tangential loading of the turbine. This factor decreases when approaching the blade tip. It has been shown that the factor should be different for the axial and tangential loading of the turbine to model the rotation of the resulting force vector at the airfoil sections caused by the induced velocity. The present article contains the derivation of a simple correction for the tangential load factor that takes this rotation into account. The correction does not need any additional curve fitting but just depends on the local airfoil characteristics and angle of attack. Actuator disc computations with the modified tip loss correction show improved agreement with results from actuator line, free wake lifting line, and blade element momentum simulations. 相似文献
5.
6.
Raimund J. Ober 《International journal of control》2013,86(4):332-344
A new approach is presented for the realization of continuous-time finite dimensional linear systems. Using standard results on Laplace transforms our results are also used to present a new derivation of Fuhrmann's shift realization for rational matrix functions. 相似文献
7.
Theme issue on personal projection 总被引:1,自引:0,他引:1
8.
9.
Andreas Mauerer Bastian Lange Goetz Hannes Welsch Frank Heidenau Werner Adler Raimund Forst Richard Heiner Richter 《Journal of materials science. Materials in medicine》2014,25(3):813-821
The aim of this study was the investigation of a copper-filled TiO2 coating, that in vitro showed good antibacterial properties combined with good tissue tolerance in an animal model. To better understand the antibacterial mechanism of the bioactive coating the release of copper (Cu) ions over time was monitored to be able to detect possible threats as well as possible fields of application. 30 New Zealand White rabbits were divided into two groups with 15 animals per group. In group 1 (control group) Ti6Al4 V bolts were implanted into the distal femur, in group 2 the Ti6Al4 V bolts were coated with four TiO2-coatings with integrated Cu2+-ions (4 × Cu–TiO2). Blood tests were performed weekly until the animals were sacrificed 4 weeks postoperative. The maximum peak of Cu and ceruloplasmin concentration could be seen in both groups one week postoperative, whereas the Cu values in group II were significantly higher. The Cu concentration in both groups approximated the initial basic values 4 weeks postoperative. The 4 × Cu–TiO2 coating tested in our rabbit model for total knee arthroplasty is an active coating that releases potentially antibacterial Cu2+ for 4 weeks with a peak 1 week postoperative. The bioactive coating could be a promising approach for a use in the field of implant related infection, orthopaedic revision and tumor surgery in the future. 相似文献
10.
Matthias Holl Timo Rogge Stefan Loehnert Peter Wriggers Raimund Rolfes 《Computational Mechanics》2014,53(1):173-188
This work presents a new multiscale technique to investigate advancing cracks in three dimensional space. This fully adaptive multiscale technique is designed to take into account cracks of different length scales efficiently, by enabling fine scale domains locally in regions of interest, i.e. where stress concentrations and high stress gradients occur. Due to crack propagation, these regions change during the simulation process. Cracks are modeled using the extended finite element method, such that an accurate and powerful numerical tool is achieved. Restricting ourselves to linear elastic fracture mechanics, the $J$ -integral yields an accurate solution of the stress intensity factors, and with the criterion of maximum hoop stress, a precise direction of growth. If necessary, the on the finest scale computed crack surface is finally transferred to the corresponding scale. In a final step, the model is applied to a quadrature point of a gas turbine blade, to compute crack growth on the microscale of a real structure. 相似文献