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排序方式: 共有599条查询结果,搜索用时 31 毫秒
1.
Akihiro Nishiguchi Fumisato Sasaki Hidehito Maeda Masayuki Kabayama Akio Ido Tetsushi Taguchi 《Small (Weinheim an der Bergstrasse, Germany)》2019,15(35)
Endoscopic submucosal dissection (ESD) provides strong therapeutic benefits for early gastrointestinal cancer as a minimally invasive treatment. However, there is currently no reliable treatment to prevent scar contracture resulting from ESD which may lead to cicatricial stricture. Herein, a multifunctional colloidal wound dressing to promote tissue regeneration after ESD is demonstrated. This sprayable wound dressing, composed of hydrophobized microparticles, exhibits the multifunctionality necessary for wound healing including tissue adhesiveness, blood coagulation, re‐epithelialization, angiogenesis, and controlled inflammation based on hydrophobic interaction with biological systems. An in vivo feasibility study using swine gastric ESD models reveals that this colloidal wound dressing suppresses fibrosis and accelerates wound healing. Multifunctional colloidal and sprayable wound dressings have an enormous therapeutic potential for use in a wide range of biomedical applications including accelerated wound healing after ESD, prevention of perforation, and the treatment of inflammatory diseases. 相似文献
2.
Takayuki Nakamura Yoshiaki Taguchi Masamichi Ogasa 《Electrical Engineering in Japan》2015,193(2):69-81
To reduce the loss due to ripple current in a multiphase current‐reversible chopper, we investigated electromagnetic coupling of an air‐core reactor. We derived the relationship between the amplitude of the ripple current, the duty factor, and the electromagnetic coupling coefficient, and used the results to estimate the effects of electromagnetic coupling in the design of a train energy storage system. We built reactors with electromagnetic coupling coefficients of 0.93 and 0.60. These reactors employed a new winding structure that provides an optimal electromagnetic coupling coefficient. The mass of the former type of reactor was increased by 4.4% over the conventional design, and that of the latter type of reactor was decreased by 17%. Finally, we tested the new reactors. When the chopper employs the former type of reactor and operates with equal‐phase switching and cumulative coupling, the loss due to ripple current is decreased by 11%. When the chopper employs the latter type of reactor and operates with shift‐phase switching and differential coupling, the loss is decreased to 31%. The test showed that the calculated relationships agreed with the measured values. 相似文献
3.
Suzuki Atsushi Taguchi Masaya Oku Takeo Okita Masanobu Minami Satoshi Fukunishi Sakiko Tachikawa Tomoharu 《Journal of Materials Science: Materials in Electronics》2021,32(22):26449-26464
Journal of Materials Science: Materials in Electronics - Fabrication and characterization of methylammonium lead iodide perovskite solar cells incorporated with methylammonium bromide (MABr),... 相似文献
4.
The Pt oxide thin film and Pt thin film were prepared by reactive sputtering and the electrocatalytic activity of the ethanol oxidation reaction was investigated in a KOH solution for developing the alkaline direct ethanol fuel cells. After electrochemical reduction by passing a cathodic electric charge, the Pt oxide thin film showed 29 times larger ethanol oxidation current than the Pt thin film. This superior activity was caused by an increase in the electrochemical active surface area and the existence of residual oxygen, which was confirmed by cyclic voltammetry and XPS measurement. Due to the contribution of the residual oxygen, the rate-determining step of the ethanol oxidation reaction might change, because the Tafel slope of the Pt oxide thin film during the ethanol oxidation reaction was changed by electrochemical reduction. Despite the total Pt amount in the Pt oxide thin film being smaller than that in the Pt thin film, the Pt oxide thin film showed excellent ethanol oxidation activity. Therefore, the Pt oxide treated by electrochemical reduction may be a promising anode catalyst for the direct ethanol fuel cells. 相似文献
5.
Makoto Sasaki Motoki Inoue Yasuyuki Katada Yuuki Nishida Akiyoshi Taniguchi Sachiko Hiromoto Tetsushi Taguchi 《Science and Technology of Advanced Materials》2012,13(6)
Calcium phosphate was formed on nickel-free high-nitrogen stainless steel (HNS) by chemical solution deposition. The calcium phosphate deposition was enhanced by glutamic acid covalently immobilized on the surface of HNS with trisuccinimidyl citrate as a linker. X-ray diffraction patterns and Fourier transform infrared spectra showed that the material deposited on glutamic acid-immobilized HNS within 24 h was low-crystallinity calcium-deficient carbonate-containing hydroxyapatite (HAp). The biological activity of the resulting HAp-coated HNS was investigated by using a human osteoblast-like MG-63 cell culture. The HAp-coated HNS stimulated the alkaline-phosphate activity of the MG-63 culture after 7 days. Therefore, HAp-coated HNS is suitable for orthopedic devices and soft tissue adhesion materials. 相似文献
6.
Takuya Matsumoto Mohammad Hafiz Uddin Sang Hyun An Kazuto Arakawa Eiji Taguchi Atsushi Nakahira Masayuki Okazaki 《Materials Chemistry and Physics》2011
Hydroxyapatite materials are potentially useful for biomedical application, especially as vehicles for functional molecules. Structural control of bulk apatite materials, such as in the fabrication of hollow microspheres or porous structures, has been studied for this purpose. However, control of the internal structure of the source apatite crystal itself is still a challenge. Here, we show that small organic molecules incorporated in apatite crystals act as porogens which control the porous structure of apatite single crystal. The presence of amino acid under apatite synthesis conditions leads to firm bindings and encapsulation of the amino acid in apatite single crystals. Amino acid elimination by heating or electron beam irradiation enhances the pore formation in apatite single crystal. Moreover, incorporation of an acidic amino acid in apatite induces peapod like nanotubes in apatite single crystals. This study suggests the potential of using small organics for nano-structural control of apatite single crystals which would be valuable for enhancing drug loadings or modulating material digestion in vivo. 相似文献
7.
Bin Zhang Tetsushi Harada Tatsuya Matsumoto Kenji Fukuda Tohru Suzuki Yoshiharu Tobita 《Nuclear Engineering and Design》2011,241(1):366-377
During a hypothetical core-disruptive accident in a sodium-cooled fast breeder reactor, degraded core materials can form debris beds on the core-support structure and/or in the lower inlet plenum of the reactor vessel from rapid quenching and fragmentation of core material pool. Coolant boiling may lead ultimately to leveling of the debris bed that is crucial to the relocation of molten core and heat-removal capability of the debris bed. In the present study, we elected to use depressurization boiling to simulate an axially increasing void distribution in the debris bed. Bottom-heating boiling was also chosen to confirm that characteristics of the self-leveling process do not depend on the boiling mode. Particle size (between 0.5 and 6 mm), shape (spherical and non-spherical), bed volume (between 5 and 8 l) and density (namely of alumina, zirconia, lead and stainless steel) along with boiling intensity and total volume were taken as experimental parameters to obtain the general characteristics of the self-leveling process. A series of experiments with simulant materials were conducted and analyzed in detail. The good concordance of the transient processes obtained from the different boiling methods sufficiently demonstrates that the present results obtained using the depressurization boiling method exhibit these general self-leveling characteristics. Detailed comparisons of deduced time variations of the inclination angle provides qualitative tendencies based on the experimental parameters considered influential to self-leveling behavior. The rationale behind the definition introduced for equivalent power density is also presented. 相似文献
8.
Fabrication and characterization of polyterpenol as an insulating layer and incorporated organic field effect transistor 总被引:1,自引:0,他引:1
A non-synthetic polymer material, polyterpenol, was fabricated using a dry polymerization process namely RF plasma polymerization from an environmentally friendly monomer and its surface, optical and electrical properties investigated. Polyterpenol films were found to be transparent over the visible wavelength range, with a smooth surface with an average roughness of less than 0.4 nm and hardness of 0.4 GPa. The dielectric constant of 3.4 for polyterpenol was higher than that of the conventional polymer materials used in the organic electronic devices. The non-synthetic polymer material was then implemented as a surface modification of the gate insulator in field effect transistor (OFET) and the properties of the device were examined. In comparison to the similar device without the polymer insulating layer, the polyterpenol based OFET device showed significant improvements. The addition of the polyterpenol interlayer in the OFET shifted the threshold voltage significantly; + 20 V to −3 V. The presence of trapped charge was not observed in the polyterpenol interlayer. This assisted in the improvement of effective mobility from 0.012 to 0.021 cm2/Vs. The switching property of the polyterpenol based OFET was also improved; 107 compared to 104. The results showed that the non-synthetic polyterpenol polymer film is a promising candidate of insulators in electronic devices. 相似文献
9.
10.
Molecular weight dependence of growth and morphology of spherulites of isotactic poly(butene-1), iPB-1, and those of the mixtures with atactic poly(butene-1), aPB-1, were examined by atomic force microscopy (AFM) and polarizing optical microscopy (POM) in order to examine the mechanism of the structural evolution by the branching and re-orientation of lamellar crystals at the growth front. The width of lamellar crystals and the characteristic size of the inner structure of spherulites decreased with increasing molecular weight. The result suggests that the mobility of the melt determines the sizes in spherulites and supports the growth front instability induced by a gradient triggering the branching. The sizes in the mixtures also decreased with increasing weight-averaged molecular weight, Mw. The size dependence in low Mw region, however, was too strong and that in high Mw was too weak in comparison with the predicted dependence for the prepared Mw. It has been concluded that the peculiar behaviors should be discussed with effective Mw influenced by the occurrence of separation and exclusion of non-crystallizing aPB-1 at the growth front. 相似文献