Context and spoken word recognition in a novel lexicon.

[Correction Notice: An erratum for this article was reported in Vol 35(1) of Journal of Experimental Psychology: Learning, Memory, and Cognition (see record 2008-18581-022). Figure 9 was inadvertently duplicated as Figure 10. Figure 9 in the original article was correct. The correct Figure 10 is provided.] Three eye movement studies with novel lexicons investigated the role of semantic context in spoken word recognition, contrasting 3 models: restrictive access, access-selection, and continuous integration. Actions directed at novel shapes caused changes in motion (e.g., looming, spinning) or state (e.g., color, texture). Across the experiments, novel names for the actions and the shapes varied in frequency, cohort density, and whether the cohorts referred to actions (Experiment 1) or shapes with action-congruent or action-incongruent affordances (Experiments 2 and 3). Experiment 1 demonstrated effects of frequency and cohort competition from both displayed and non-displayed competitors. In Experiment 2, a biasing context induced an increase in anticipatory eye movements to congruent referents and reduced the probability of looks to incongruent cohorts, without the delay predicted by access-selection models. In Experiment 3, context did not reduce competition from non-displayed incompatible neighbors as predicted by restrictive access models. The authors conclude that the results are most consistent with continuous integration models. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

The granaticin biosynthetic gene cluster of Streptomyces violaceoruber Tü22: sequence analysis and expression in a heterologous host

BACKGROUND: The granaticins are members of the benzoisochromanequinone class of aromatic polyketides, the best known member of which is actinorhodin made by Streptomyces coelicolor A3(2). Genetic analysis of this class of compounds has played a major role in the development of hypotheses about the way in which aromatic polyketide synthases (PKSs) control product structure. Although the granaticin nascent polyketide is identical to that of actinorhodin, post-PKS steps involve different pyran-ring stereochemistry and glycosylation. Comparison of the complete gene clusters for the two metabolites is therefore of great interest. RESULTS: The entire granaticin gene cluster (the gra cluster) from Streptomyces violaceoruber T-22 was cloned on either of two overlapping cosmids and expressed in the heterologous host, Streptomyces coelicolor A3(2), strain CH999. Chemical analysis of the recombinant strains demonstrated production of granaticin, granaticin B, dihydrogranaticin and dihydrogranaticin B, which are the four known metabolites of S. violaceoruber. Analysis of the complete 39,250 base pair sequence of the insert of one of the cosmids, pOJ466-22-24, revealed 37 complete open reading frames (ORFs), 15 of which resemble ORFs from the act (actinorhodin) gene cluster of S. coelicolor A3(2). Among the rest, nine resemble ORFs potentially involved in deoxysugar metabolism from Streptomyces spp. and other bacteria, and six resemble regulatory ORFs. CONCLUSIONS: On the basis of these resemblances, putative functional assignments of the products of most of the newly discovered ORFs were made, including those of genes involved in the PKS and tailoring steps in the biosynthesis of the granaticin aglycone, steps in the deoxy sugar pathway, and putative regulatory and export functions.     

"Context and spoken word recognition in a novel lexicon": Correction.

Reports an error in "Context and spoken word recognition in a novel lexicon" by Kathleen Pirog Revill, Michael K. Tanenhaus and Richard N. Aslin (Journal of Experimental Psychology: Learning, Memory, and Cognition, 2008[Sep], Vol 34[5], 1207-1223). Figure 9 was inadvertently duplicated as Figure 10. Figure 9 in the original article was correct. The correct Figure 10 is provided. (The following abstract of the original article appeared in record 2008-11850-014.) Three eye movement studies with novel lexicons investigated the role of semantic context in spoken word recognition, contrasting 3 models: restrictive access, access-selection, and continuous integration. Actions directed at novel shapes caused changes in motion (e.g., looming, spinning) or state (e.g., color, texture). Across the experiments, novel names for the actions and the shapes varied in frequency, cohort density, and whether the cohorts referred to actions (Experiment 1) or shapes with action-congruent or action-incongruent affordances (Experiments 2 and 3). Experiment 1 demonstrated effects of frequency and cohort competition from both displayed and non-displayed competitors. In Experiment 2, a biasing context induced an increase in anticipatory eye movements to congruent referents and reduced the probability of looks to incongruent cohorts, without the delay predicted by access-selection models. In Experiment 3, context did not reduce competition from non-displayed incompatible neighbors as predicted by restrictive access models. The authors conclude that the results are most consistent with continuous integration models. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Planar Alignment of Columnar Discotic Liquid Crystals by Isotropic Phase Dewetting on Chemically Patterned Surfaces

A novel method of creating planar aligned columnar discotic liquid crystals (cDLCs) on surfaces, which also gives control over the azimuthal angle, is presented. Surfaces are chemically patterned with stripes via microcontact printing of organothiol self‐assembled monolayers (SAMs) on gold, or via deep UV patterning of organosilane SAMs on silicon. These are then used to isolate long droplets of cDLCs by dewetting in the isotropic phase. Upon cooling from the isotropic into the hexagonal columnar phase, polarizing microscopy reveals that the cDLC aligns in a planar orientation. Results for three triphenylene derivatives (HAT‐6, HHTT, H7T) and for a phthalocyanine derivative (8H₂Pc) are presented. H7T and HAT‐6 are found to align with the director perpendicular to the stripe direction, but HHTT and 8H₂Pc align parallel to the stripe direction. This relatively simple new method for creating planar aligned columnar phases of DLCs gives control over the azimuthal angle: a condition required for organic field‐effect transistor applications of cDLCs.     

Landscapes of defence

This paper introduces a set of four papers that deal with aspects of 'landscapes of defence'—landscapes shaped or otherwise materially affected by formal or informal defensive strategies to achieve recognizable social, political or cultural goals. It comprises three main sections. The first surveys various ways in which strategies to achieve defence against other people or against nature have shaped the landscape. The second section surveys research on human territoriality, a kindred area of inquiry, to see what lessons can be learned about the nature of defended spaces and places in human affairs. The final section introduces the four papers in this theme issue. These deal respectively with the landscapes associated with four 'nuclear oases' (Blowers), current planning and urban design approaches to security in the urban environment (Oc and Tiesdell), children's fears and concerns about places in the city centre (Woolley et al.), and the spatial significance of military defence landscapes in the UK (Tivers).     

The nucleotide sequence and genome organization of mushroom bacilliform virus: a single-stranded RNA virus of Agaricus bisporus (Lange) Imbach

Mushroom bacilliform virus (MBV) is found in association with spherical virus-like particles in cultivated mushrooms (Agaricus bisporus) afflicted with La France disease. MBV possesses a monopartite ssRNA genome of positive sense and differs from the majority of characterized mycoviruses, which contain segmented dsRNA genomes. We have cloned and sequenced the MBV genome and determined that its length is 4009 nucleotides. The MBV genome contains four major and three minor open reading frames and has 5' and 3' noncoding regions of 60 and 250 nucleotides, respectively. The putative RNA-dependent RNA polymerase and the coat protein display homology with corresponding proteins encoded by certain plant viruses, particularly luteoviruses and carmoviruses.