四种药用植物抑菌作用初探

本文对药用植物的抑菌作用进行了研究，测试了不同药用植物对细菌的抑菌圈大小、最低抑菌浓度及最低杀菌浓度，试验了提取成分对热的稳定性。结果发现：小檗色素对大肠杆菌抑菌作用最强，酸浆花萼色素对变彤杆菌抑菌作用最强，红景天浓缩液对枯草芽孢杆菌抑菌作用最强，小茼香浓缩液对四种待试菌无抑菌作用；小檗色素对四种待试菌的最低抑菌浓度和最低杀菌浓度分别为：枯草芽孢杆菌MIC2．5％、MBC5．0％，大肠杆菌MIC5．0％、MBC5．0％，金黄色葡萄球菌MIC2．5％、MBC5．0％，变形杆菌MICl．25％、MBC1．25％；酸浆花萼色素的最低抑菌浓度和最低杀菌浓度分别为：枯草芽孢杆菌MIC4．18％、MBC4．18％，大肠杆菌MIC8．35％、MBC8．35％，金黄色葡萄球菌MIC4．18％、MBC4．18％，变形杆菌MIC4．18％、MBC8．35％；红景天浓缩液的最低抑菌浓度和最低杀菌浓度分别为：枯草芽孢杆菌MIC2．09％、MBC4．18％，大肠杆菌MIC2．09％、MBC2．09％，金黄色葡萄球菌MIC8．35％、MBC8．35％，变形杆菌MIC4．18％、MBC8．35％。小檗色素、酸浆花萼色素和红景天浓缩液抑菌成分对高温稳定，抑菌机理尚待研究。

Primary Antibiotic Investigation of Four Pharmaceutical Plants

This paper studied on antimicrobial effect of medical plant. In other words, the antimicrobial circle, MIC and MBC were tested. The extracted constituents showed stability against high temperature. The results showed: the Berberis heteropoda pigment could effectively inhibit the growth of theE scherichiac oli, the calyx pigment ofP hysalis alkekengi coulde ffectively inhibit the growth of the Bacterium proteus, the concentrated liquid of Rhodiola sachalinensis could effectively inhibit the growth of the Bacillus subitilis, the concentrated liquid of Foeniculum vulgare Mill has no antimicrobial effect on the four bacteria.The MIC and MBC of the Berberis heteropoda pigment affecting 4 species of bacteria respectively were: and Bacillus subitilis: MIC 2. 5%, MBC 5.0%, Escherichia coli: MIC 5.0%, MBC 5.0%, Staphylococcus aurous: MIC 2.5%, MBC 5.0%, Bacterium proteus: MIC 1.25%, MBC 1.25%. The MIC and MBC of the calyx pigment of Physalis alkekengi respectively were: Bacillus subitilis: MIC 4.18%, MBC 4.18%, Escherichia coli: MIC 8.35%, MBC 8.35%, Staphylococcus aurous: MIC 4.18%, MBC 4.18%, and Bacterium proteus: MIC 4.18%, MBC 8.35%. The MIC and MBC of the concentrated liquid of Rhodiola sachalinensis respectively were: Bacillus subitilis: MIC 2.09%, MBC 4.18%, Escherichia coli: MIC 2.09%, MBC 2.09%, Staphylococcus aurous: MIC 8.35%, MBC 8.35%, and Bacterium proteus: MIC 4.18%, MBC 8.35%. The antimicrobial activity of the three extracts under high temperature was stable. However, the antimicrobe mechanism needed further study.