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Bioactivity of mica/apatite glass ceramics
作者姓名:冯云枝  王压冲  谭燕妮  刘咏  向其军  盛小娴
作者单位:[1]Department of Stomatology, Xiangya Second Hospital, Central South University, Changsha 410011, China [2]State Key Laboratory of Powder Metallurgy, Central South University, Changsha 410083, China
摘    要:

关 键 词:云母/磷灰石玻璃陶瓷  生物活性  骨传导率  生物材料
收稿时间:21 March 2007
修稿时间:2007-03-212007-05-31

Bioactivity of mica/apatite glass ceramics
FENG Yun-Zhi,WANG Ya-chong,TAN Yan-ni,LIU Yong,XIAN Qi-jun,SHENG Xiao-xian.Bioactivity of mica/apatite glass ceramics[J].Transactions of Nonferrous Metals Society of China,2007,17(4):828-831.
Authors:FENG Yun-Zhi  WANG Ya-chong  TAN Yan-ni  LIU Yong  XIAN Qi-jun  SHENG Xiao-xian
Affiliation:1. Department of Stomatology, Xiangya Second Hospital, Central South University, Changsha 410011, China; 2. State Key Laboratory of Powder Metallurgy, Central South University, Changsha 410083, China
Abstract:The bioactivity of mica/apatite glass ceramic composites, including the in vitro behavior in simulated body fluid and the histological appearance of the interface between the mica/apatite glass ceramics and the rabbit mandible defect in vivo under a dynamic condition. The results show that biological apatite layer forms on the surface of the mica/apatite glass ceramics after l d of immersion in the simulated body fluid, and becomes dense after 14 d. In vivo tests indicate that bone formation occurs after implantation for 14 d, and strong bonding of bone to the implant occurs after 42 d. No aseptic loosening occurs during 42 d of implantation. The finding shows that mica/apatite glass ceramics have good bioactivity and osteoconductivity for constructing bone graft, and can be promising for biomedical application.
Keywords:mica/apatite glass ceramics  bioactivity  osteoconductivity
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