Comparative study of the influence of active groups of chitosan derivatives on antifungal activity |
| |
| Authors: | Zhanyong Guo Jianming Ren Fang Dong Gang Wang Pengcheng Li |
| |
| Affiliation: | 1. Yantai Institute of Coastal Zone Research, Chinese Academy of Sciences, Yantai 264003, China;2. Graduate University of Chinese Academy of Sciences, Beijing 100039, China;3. Email:pcli@ ms.qdio.ac.cn;6. Institute of Oceanology, Chinese Academy of Sciences, Qingdao 266071, China |
| |
| Abstract: | In this study, series of chitosan derivatives containing active groups were synthesized and evaluated for their antifungal activity against three crop‐threatening fungi, Fusarium oxysporum. f. sp. Vasinfectum, Alternaria solani, and Valsa mali. Schiff bases of carboxymethyl chitosan (As: 2‐(2‐hydroxy‐5‐nitrobenzylideneamino)‐6‐carboxymethyl chitosan; Bs: 2‐(2‐hydroxyl‐5‐chlorobenzaldimino)‐6‐carboxymethyl chitosan), N‐substituted carboxymethyl chitosan (An: 2‐(2‐hydroxyl‐5‐nitrobenzylamino)‐6‐carboxymethyl chitosan; Bn: 2‐(2‐hydroxyl‐5‐chlorobenzylamino)‐6‐carboxymethyl chitosan) and 2‐urea‐carboxymethyl chitosan (Au: 2‐(2‐nitrophenylurea)‐6‐carboxymethyl chitosan; Bu: 2‐(2‐chlorophenylurea)‐6‐carboxymethyl chitosan) were synthesized, and their antifungal activity was comparatively studied by hypha measurement in vitro, respectively. Results obtained from this study revealed that the active groups combined with Schiff bases functional groups (C?N) could strengthen the antifungal activity most effectively among the compounds studied in this work. © 2012 Wiley Periodicals, Inc. J. Appl. Polym. Sci., 2013 |
| |
| Keywords: | active groups chitosan antifungal activity |
|
|
