中国母乳组学队列研究与产业化应用

母乳为婴儿提供个性化、全面、均衡的营养成分以及免疫保护，是0～6月婴儿的最佳营养来源，是婴儿食物的金标准。母乳组学队列研究是全面解析中国母乳组成特征、建立中国婴儿食品规范与标准、制定婴儿营养指南、创制婴儿食品的必要前提。本文介绍了国家母婴乳品健康工程技术研究中心基于中国母婴营养健康出生队列研究（China maternal and infant nutrition health birth cohort study,MINC）的母乳脂质组学、糖组学、蛋白质组学和微生物组等组学检测技术、组成特征、与牛乳的差异及其在婴儿食品中的产业化应用等方面的研究进展，以期为母乳组学队列研究、模拟与产业化应用提供科技支撑与示范。

Chinese Human Milk Omics: Cohort Study and Industrial Application

Human milk, which provides personalized, comprehensive, and balanced nutrients, and immune protection, is the best nutritional source for 0~6 month-old infants, and it is the gold standard for infant food. A cohort study of human milk omics is a necessary prerequisite for comprehensively analyzing the composition and characteristics of Chinese human milk, establishing Chinese infant food norms and standards, developing infant nutrition guidelines, and creating infant foods. This article presents the research progress of the National Engineering Research Center of Dairy Health for Maternal and Child pertaining to the China Maternal and Infant Nutrition Health Birth Cohort Study (MINC) in terms of breast milk lipidomics, glycomics, proteomics, and microbiomics detection techniques, composition characteristics, differences from bovine milk, and industrial applications in infant food. This will lay a science and technical support for the omics research of Chinese human milk and provide the necessary data and demonstration for industrial application.