| 光甘草定微胶囊包合物制备 |
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| 引用本文： | 林万泉,陈俊昭,赵月美,朱连杰,黄小茉,邱晓颖.光甘草定微胶囊包合物制备[J].日用化学品科学,2014(12):34-39. |
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| 作者姓名： | 林万泉 陈俊昭 赵月美 朱连杰 黄小茉 邱晓颖 |
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| 作者单位： | 广东迪美生物技术有限公司;广东省微生物研究所省部共建华南应用微生物国家重点实验室;广东省菌种保藏与应用重点实验室; |
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| 摘 要： | 研究以明胶和阿拉伯胶为壁材,采用复凝聚法研究了光甘草定微胶囊的制备工艺,探讨了芯壁质量比、增溶剂使用量、乳液均质时间和搅拌速度的影响,通过正交试验确定最佳工艺条件为芯壁比为2∶1,增溶剂为0.5%,均质时间为10 min,搅拌速度为750 r/min。通过本工艺制备得到的光甘草定微胶囊包裹率可达40%,粒径分布均匀(平均粒径3.91μm),将其喷雾干燥后得到光甘草定微胶囊粉末为淡黄色,无刺激气味,可溶于丙二醇等有机溶剂。包裹后的光甘草定微胶囊,减淡了原有的棕黑颜色和刺鼻气味,可很好地用作化妆品美白添加剂。
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| 关 键 词： | 化妆品 美白添加剂 光甘草定 复凝聚法 微胶囊 |
Preparation of microcapsule inclusion complex of glabridin |
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| Affiliation: | LIN Wan-quan, CHEN Jun-zhao, ZHAO Yue-mei, ZHU Lian-jie, HUANG Xiao-mo, QIU Xiao-ying (1. Guangdong Demay Biological Technology Co., Ltd., Guangzhou, Guangdong 510663, China; 2. Guangdong Institute of Microbiology, State Key Laboratory of Applied Microbiology Southern China, Guangdong Provincial Key Laboratory of Microbial Culture Collection and Application, Guangzhou, Guangdong 510070, China) |
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| Abstract: | Glabridin, as a kind of natural compound, has obvious antioxidant and whitening activity and other biological activities. Glabridin microcapsule was prepared in this study by complex coacervation method with gelatin and gum arabic as wall materials. The technological condition was studied through orthogonal experiment, and the optimal condition was confirmed as follows. The ratio of core to wall was 2 ： 1, concentration of solubilizer was 0.5 %, homogeneous time was 10 rain and stirring rate was 750 r/min. The results showed that encapsulation of glabridin could reach to 40% of total and the grain size was uniform （average grain size was 3.91 μm）. The powder of glabridin microcapsule after spray drying was faint yellow color with no irritant smell and soluble in propylene glycol as well as other organic solvents. |
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| Keywords: | cosmetic skin whitening additive glabridin complex coacervation method microcapsule |
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