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Dithiocarbamate as an efficient intermediate for the synthesis of 2-(alkylthio)thiazol-4(5H)-ones |
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| Authors: | Azim Ziyaei Halimehjani M Ali Alaei Farzaneh Soleymani Movahed Negin Jomeh Mohammad R Saidi |
| Affiliation: | 1. Faculty of Chemistry, Kharazmi University, Tehran, Iran;2. Department of Chemistry, Sharif University of Technology, Tehran, Iran |
| Abstract: | An effective approach for the synthesis of 2-(alkylthio)thiazol-4(5H)-ones from alkyl dithiocarbamates and chloroacetyl chloride in the presence of NaHCO3 has been developed. Good to excellent yields of products, simple reaction conditions and general applicability are the most important advantages of this protocol. |
| Keywords: | Dithiocarbamate 2-(alkylthio)thiazol-4(5H)-ones heterocycles chloroacetyl chloride carbon disulfide |