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微波辐照诱发Wistar大鼠外周血淋巴细胞亚群变化
引用本文:尹金玲,满其航,崔玉芳,杜丽,马琼.微波辐照诱发Wistar大鼠外周血淋巴细胞亚群变化[J].辐射防护通讯,2011,31(4):19-22.
作者姓名:尹金玲  满其航  崔玉芳  杜丽  马琼
作者单位:1. 航天中心医院职业病科,北京,100049
2. 军事医学科学院放射与辐射医学研究所,北京,100850
基金项目:国家自然科学基金(39000386)毫米波国家重点实验室开放课题(K200909)军队医药卫生“十一五”基金
摘    要:采用微波辐照雄性清洁级Wistar大鼠,观察其对大鼠外周血淋巴细胞亚群的影响。实验结果显示:与对照组相比,10mW/cm2组、30mW/cm2组照射后第7天,5mW/cm2组、10mW/cm2组、30mW/cm2组照射后第14天,CD3+降低显著;10mW/cm2组照射后第14天,CD4+降低显著。各辐照组照射后第1、...

关 键 词:微波  淋巴细胞  大鼠

Effects of Microwave Radiation on Lymphocyte Subpopulations in Rat Peripheral Blood
Yin Jinling Man QihangAerospace Center Hospital,Beijing,Cui Yufang Du Li Ma Qiong.Effects of Microwave Radiation on Lymphocyte Subpopulations in Rat Peripheral Blood[J].Radiation Protection Bulletin,2011,31(4):19-22.
Authors:Yin Jinling Man QihangAerospace Center Hospital  Beijing  Cui Yufang Du Li Ma Qiong
Affiliation:(Beijing Institute of Radiation Medicing,Beijing,100850)
Abstract:CD3 + cells in 10 - 30 mW/cm2 groups at 7 d and in 5 - 30 mW/cmz groups at 14 d and CD4+ T subset in 10 roW/cm2 group at 14 d post radiation were all decreased signifieantiy as compared with control groups. 1 to 14 d after radiation, CD8+ T cells in all irradiated groups showed reduction, however, only that in 30 mW/cm2 group reduced statistically when compared with control group. CIM+/CD8+ ratios in 5 mW/cm2 group at ld and in 5 - 30 mW/cm2 groups at 14 d post radiation were all diminished statistically as compared with control groups. After microwave exposure, CIM5RA+ B cells showed opposite change to the T cells, for instance, CD45RA+ B cells in 30 mW/emz group at 1 d and in 30 - 60 mW/cm2 groups at 14 d post radiation increased significantly, which showed better dose-effect relationship 14 d after irradiation.
Keywords:Microwave Rat Lymphocyte subpopulations
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