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利用洛伐他汀选育高产β-胡萝卜素的三孢布拉霉菌株
引用本文:刘海丽,王蓓,余晓斌.利用洛伐他汀选育高产β-胡萝卜素的三孢布拉霉菌株[J].食品与机械,2005,21(5):10-11.
作者姓名:刘海丽  王蓓  余晓斌
作者单位:江南大学生物工程学院,江苏,无锡,214036;江南大学工业生物技术教育部重点实验室,江苏,无锡,214036
基金项目:江南大学青年科学基金资助项目(1010130-52210468)
摘    要:β-胡萝卜素为类萜化合物,是重要的VA的前体,并具有较强的抗氧化作用,在食品、保健品、化妆品以及医药领域具有重要用途。利用三孢布拉霉(Blakeslea trispora)发酵生产天然β-胡萝卜素最有应用前景。我们利用含有洛伐他汀(lovastatin)和OP乳化剂或脱氧胆酸钠(SDC)的平板实现了对高产菌株的选育,方法简单,效果明显。

关 键 词:β-胡萝卜素  洛伐他汀  三孢布拉霉  天然β-胡萝卜素  高产菌株  选育  抗氧化作用  脱氧胆酸钠  OP乳化剂  医药领域
收稿时间:2005-06-13
修稿时间:2005年6月13日

A new method to select desired Blakeslea Trispora with lovastatin
LIU Hai-li,WANG Bei,YU Xiao-bin.A new method to select desired Blakeslea Trispora with lovastatin[J].Food and Machinery,2005,21(5):10-11.
Authors:LIU Hai-li  WANG Bei  YU Xiao-bin
Affiliation:1. College of Vniversity, Wuxi Jiangsu 2140338, China, Southern Yangtze University; 2. The Key Laboratory of Industrial Biotechnology, Ministry of Education, Southern Yangtze University, Wuxi Jiangsu 214036, China
Abstract:Beta-carotene is a pigment of isoprenoid naturally synthesized by certain microorganisms.In addition to serve as a precursor of Vitamin A (retinol),beta-carotene is also an effective antioxidant.It can be applied to many fields,such as food products and cosmetics.Blakeslea trispora is well known for its high production of beta-carotene.We report a useful method with an effective agent-lovastatin-in selecting of desired microorganisms.
Keywords:Beta-carotene  Lovastatin  Blakeslea trispora
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