| 羧甲基硫脲壳聚糖的结构表征及抑菌活性研究 |
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| 引用本文： | 李小芳,马金满,冯小强,王廷璞,杨声,张红娟,孔旭娥.羧甲基硫脲壳聚糖的结构表征及抑菌活性研究[J].食品科学,2012,33(1):64-67. |
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| 作者姓名： | 李小芳 马金满 冯小强 王廷璞 杨声 张红娟 孔旭娥 |
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| 作者单位： | 天水师范学院生命科学与化学学院;甘谷一中 |
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| 基金项目： | 天水师院物理无机化学重点学科基金项目(ZD0840),天水师院“青蓝”人才工程和中青年教师科研资助项目(TSA1003) |
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| 摘 要： | 运用红外光谱、紫外光谱和差热-热重分析对合成的羧甲基硫脲壳聚糖进行结构表征,并研究羧甲基硫脲壳聚糖对大肠杆菌、金黄色葡萄球菌的抑菌活性。结果表明:硫脲壳聚糖中羟基发生了羧甲基化反应,与壳聚糖相比热稳定性降低;羧甲基硫脲壳聚糖对大肠杆菌、金黄色葡萄球菌的抑菌活性较壳聚糖本身增强,对大肠杆菌、金黄色葡萄球菌最小抑菌质量浓度(MIC)均为0.20mg/mL。
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| 关 键 词： | 壳聚糖 羧甲基硫脲壳聚糖 表征 抑菌活性 |
Structural Characterization and Antibacterial Activity of Carboxymethyl Thiourea Chitosan |
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| LI Xiao-fang,MA Jin-man,FENG Xiao-qiang,WANG Ting-pu,YANG Sheng,ZHANG Hong-juan,KONG Xu-e.Structural Characterization and Antibacterial Activity of Carboxymethyl Thiourea Chitosan[J].Food Science,2012,33(1):64-67. |
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| Authors: | LI Xiao-fang MA Jin-man FENG Xiao-qiang WANG Ting-pu YANG Sheng ZHANG Hong-juan KONG Xu-e |
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| Affiliation: | 1(1.College of Life Science and Chemistry,Tianshui Normal University,Tianshui 741001,China; 2.No.1 Middle School of Gangu,Gangu 741200,China) |
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| Abstract: | Carboxymethyl thiourea chitosan(CMTCS) was prepared and characterized by infrared spectrometry(FT-IR),ultraviolet spectrometry(UV) and differential thermal and thermogravimetry analysis(TG-DTA) methods.The antibacterial activity of CMTCS against E.coli and St.aureus were investigated in vitro.The results showed that the antibacterial activity of CMTCS was obviously higher than that of chitosan with an MIC of 0.20 mg/mL against both E.coli and St.aureus. |
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| Keywords: | chitosan carboxymethyl thiourea chitosan characterization antibacterial activity |
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