| O-羧甲基化壳聚糖季铵盐的制备及抑菌活性 |
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| 引用本文： | 李小芳,冯小强,杨声,马治军,徐本锦.O-羧甲基化壳聚糖季铵盐的制备及抑菌活性[J].食品科学,2011,32(9):79. |
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| 作者姓名： | 李小芳 冯小强 杨声 马治军 徐本锦 |
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| 作者单位： | 天水师范学院生命科学与化学学院; |
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| 基金项目： | 甘肃天水师范学院物理无机化学重点学科基金资助项目(ZD0840) |
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| 摘 要： | 目的:制备抑菌活性较壳聚糖强的水溶性壳聚糖衍生物。方法:以3-氯-2-羟丙基三甲基氯化铵(CTA)和氯乙酸为接枝改性剂,制备水溶性O-羧甲基化壳聚糖季铵盐,采用红外光谱和紫外光谱对其结构进行表征,并研究O-羧甲基化壳聚糖季铵盐对大肠杆菌(E.coli)、金黄色葡萄球菌(S.aureus)和黑曲霉(A.niger)的抑制作用。结果:水溶性的O-羧甲基化壳聚糖季铵盐对E.coli、S.aureus和A.niger均有显著的抑菌活性。结论:与壳聚糖相比,水溶性的O-羧甲基化壳聚糖季铵盐的抑菌活性提高。
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| 关 键 词： | 壳聚糖 羧甲基 季铵盐 抑菌 |
Preparation and Antibacterial Activity of Water-soluble O-Carboxymethyl Chitosan Quaternary Ammonium Salt |
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| LI Xiao-fang,FENG Xiao-qiang,YANG Sheng,MA Zhi-jun,XU Ben-jin.Preparation and Antibacterial Activity of Water-soluble O-Carboxymethyl Chitosan Quaternary Ammonium Salt[J].Food Science,2011,32(9):79. |
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| Authors: | LI Xiao-fang FENG Xiao-qiang YANG Sheng MA Zhi-jun XU Ben-jin |
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| Affiliation: | LI Xiao-fang,FENG Xiao-qiang,YANG Sheng,MA Zhi-jun,XU Ben-jin(College of Life Science and Chemistry,Tianshui Normal University,Tianshui 741001,China) |
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| Abstract: | Objective: To prepare and structurally characterize water-soluble O-carboxymethyl chitosan quaternary ammonium salt(CMCQAS),and to evaluate its antibacterial activity.Method: The preparation of water-soluble CMCQAS was conducted by using 3-chloro-2-hydroxypropyl trimethyl ammonium chloride(CTA) and chloroacetic acid as grafting agents.Its structure was characterized by IR and ultraviolet spectroscopy and its antibacterial activitiy against S.aureus,E.coli and A.niger were evaluated.Results: The prepared wat... |
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| Keywords: | chitosan carboxymethyl quaternary ammonium salt antibacterial activity |
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