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壳聚糖镧配合物的制备、表征及其抑菌性能
引用本文:冯小强,李小芳,杨声,伏国庆,王廷璞,苏中兴.壳聚糖镧配合物的制备、表征及其抑菌性能[J].食品工业科技,2010(2).
作者姓名:冯小强  李小芳  杨声  伏国庆  王廷璞  苏中兴
作者单位:1. 天水师范学院生化学院,甘肃天水,741001
2. 天水市中医医院,甘肃天水,741001
3. 兰州大学化学化工学院,甘肃兰州,730000
基金项目:天水师范学院院立项目; 物理无机化学重点学科资助项目
摘    要:合成了不同配比的壳聚糖镧配合物,运用FT-IR、UV、TG-DTA和循环伏安法进行了表征。测试了壳聚糖及其镧配合物对埃希氏大肠杆菌和金黄色葡萄球菌的抑菌性能。结果表明,壳聚糖镧配合物的抑菌性能较壳聚糖有明显提高,抑菌性能随镧与壳聚糖配比的增大而增强。壳聚糖镧配合物处理后的E.coli和St.aureus的细胞壁、膜被损坏,外部有内容物溢出,表明壳聚糖镧配合物首先作用于细菌细胞壁膜,进而进入菌体内部而起到抑菌作用。

关 键 词:壳聚糖  壳聚糖镧配合物  制备  表征  抑菌性能  

Synthesis,characterization and antibacterial activity of chitosan-La(Ⅲ)complexes
FENG Xiao-qiang,LI Xiao-fang,YANG Sheng,FU Guo-qing,WANG Ting-pu,SU Zhong-xing.Synthesis,characterization and antibacterial activity of chitosan-La(Ⅲ)complexes[J].Science and Technology of Food Industry,2010(2).
Authors:FENG Xiao-qiang  LI Xiao-fang  YANG Sheng  FU Guo-qing  WANG Ting-pu  SU Zhong-xing
Affiliation:FENG Xiao-qiang1,LI Xiao-fang1,YANG Sheng1,FU Guo-qing2,WANG Ting-pu1,SU Zhong-xing3(1.College of Biology , Chemistry,Tianshui Normal Univerity,Tianshui 741001,China,2.Tianshui Traditional Chinese Medical Hospital,3.Chemistry , Chemical Engineering College,Lanzhou University,Lanzhou 730000,China)
Abstract:Chitosan-La(Ⅲ)complexes with different ratios were synthesized.The structures of these complexes were characterized by FT-IR,UV and TG-DTA.Moreover,the antibacterial activity of ohitosan and its chelae complexes against Ecoli and SLaureus were investigated in vitro.The results indicated that the antibacterial activity of chitosan chelate complexes was markedly improved compared with chitosan,and which was related to the ratio of chitosan to La(Ⅲ).The cell wall and membrane of Ecoil and St.aureus were destroyed after treated by chitosan-La(Ⅲ)complexes.
Keywords:chitosan  chitosan-La(Ⅲ)complexes  synthesize  characterization  antibacterial activity
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