熊果苷的药理作用及机制研究进展

熊果苷由于具美白、祛除色素的特性以及抗氧化、抗微生物、抗炎活性等药理作用,被广泛应用于化妆品和制药行业。近年来,熊果苷在改善葡萄酒香气等食品领域中也有一定的应用,对其安全性、营养价值等方面的研究报道越来越多。随着人们对食疗和保健的重视,许多药品也向着药食同源的方向发展,故熊果苷在食品、保健品方面具有广阔的开发前景。该文从国内外熊果苷的药理作用及机制的研究成果出发,归纳了熊果苷祛除色素、抗氧化、抗炎、抑菌、镇咳、祛痰、平喘、抗癌、放射防护、冷冻保护等药理作用及机制的主要研究进展,讨论了熊果苷作用的类型、影响因素、过程机理和作用效果。并在此基础上,对熊果苷的研究前景进行了展望。

Research progress on the pharmacological action and mechanism of arbutin

Arbutin is widely used in the cosmetics and pharmaceutical industry due to its whitening and pigment removing properties, and pharmacological effects such as antioxidant, anti-microbial and anti-inflammatory activities. In recent years, it has also been used in improving wine aroma and other food. As people′s emphasis on diet and health care, many drugs also develop usage in food. Based on the research results of the pharmacological activities and mechanism of arbutin at home and abroad, this paper summarized the main research progress of the pharmacological activities and mechanisms of arbutin in removing pigment, anti-oxidation, anti-inflammation, bacteriostasis, antitussive, expectorant, antiasthmatic, anti-cancer, radiological protection and cryo-protection, discussed the types of arbutin effect, influence factors, mechanism and effect of the process. On this basis, the research prospect of arbutin was prospected.