A Versatile Theranostic Nanoemulsion for Architecture‐Dependent Multimodal Imaging and Dually Augmented Photodynamic Therapy

To design a clinically translatable nanomedicine for photodynamic theranostics, the ingredients should be carefully considered. A high content of nanocarriers may cause extra toxicity in metabolism, and multiple theranostic agents would complicate the preparation process. These issues would be of less concern if the nanocarrier itself has most of the theranostic functions. In this work, a poly(ethylene glycol)‐boron dipyrromethene amphiphile (PEG‐F₅₄‐BODIPY) with 54 fluorine‐19 (¹⁹F) is synthesized and employed to emulsify perfluorohexane (PFH) into a theranostic nanoemulsion (PFH@PEG‐F₅₄‐BODIPY). The as‐prepared PFH@PEG‐F₅₄‐BODIPY can perform architecture‐dependent fluorescence/photoacoustic/¹⁹F magnetic resonance multimodal imaging, providing more information about the in vivo structure evolution of nanomedicine. Importantly, this nanoemulsion significantly enhances the therapeutic effect of BODIPY through both the high oxygen dissolving capability and less self‐quenching of BODIPY molecules. More interestingly, PFH@PEG‐F₅₄‐BODIPY shows high level of tumor accumulation and long tumor retention time, allowing a repeated light irradiation after a single‐dose intravenous injection. The “all‐in‐one” photodynamic theranostic nanoemulsion has simple composition, remarkable theranostic efficacy, and novel treatment pattern, and thus presents an intriguing avenue to developing clinically translatable theranostic agents.     

Input-to-state learning of recurrent neural networks with delay and disturbance

This article deals with the issue of input-to-state stabilization for recurrent neural networks with delay and external disturbance. The goal is to design a suitable weight-learning law to make the considered network input-to-state stable with a predefined -gain. Based on the solution of linear matrix inequalities, two schemes for the desired learning law are presented via using decay-rate-dependent and decay-rate-independent Lyapunov functionals, respectively. It is shown that, in the absence of external disturbance, the proposed learning law also guarantees the exponential stability of the network. To illustrate the applicability of the present weight-learning law, two numerical examples with simulations are given.     

Corrosion behaviour and mechanism of 6082 aluminium alloy in NaCl and Na2SO4 etchants

The corrosion behaviour of 6082 aluminium alloy was studied by measuring the electrochemical impedance spectra and electrode polarization curves. After the electrochemical tests, a microstructural analysis of the samples was conducted by using optical microscopy and electron scanning microscopy techniques to determine the corrosion mechanism. The results show that the Nyquist plot of the electrochemical impedance data in the NaCl solution consists of high- and low-frequency capacitive impedance loops. When ions are added to the NaCl etchant, the Nyquist plots of the electrochemical impedance data are composed of two different curves: a high-frequency capacitive impedance loop and a low-frequency inductive impedance loop. The corrosion current density increases with increasing concentration, and as a result, the corrosion resistance of the aluminium alloy decreases. The microstructures of 6082 aluminium alloy consist of Mg₂Si secondary particles in a large α-Al matrix. Pitting corrosion initially occurs at the boundary between the matrix and secondary particles because the electrode potentials of the matrix and secondary particles are different. Then, corrosion paths develop along the network-like grain boundaries, and finally, massive network-like corrosion occurs throughout the entire alloy.     

Effects of Agaricus bisporus on gel properties of chicken myofibrillar protein

The gel-forming ability of myofibrillar protein (MP) is highly correlated with the characteristics of emulsified meat products. Incorporation of Agaricus bisporus (Ab) powder into MP gels may enhance its gel properties to facilitate the development of a novel and safe meat product. Therefore, this study investigated the effects of Ab powder on gel strength, water holding capacity (WHC), texture, rheological behaviour, LF-NMR spin–spin relaxation (T₂), microstructure and protein secondary structure of the MP gel system. The results indicated that the gel strength, WHC, G' value and G" value were significantly improved when the addition of Ab powder increased from 0% to 6% (P < 0.05). Meanwhile, the T₂ relaxation time was shortened, and free water was transformed into immobilised water. The texture of the gel was improved when 1%–4% Ab powder was added compared to the control. Furthermore, Ab filled in the gel network and promoted the unfolding of MP α-helix and the formation of MP β-sheet during the thermal denaturation of MP, leading to a dense aggregated network structure. The study suggested that Ab could be a promising ingredient in improving chicken MP's gel properties and developing fat-reduced meat products.     

岩体质量的可拓学评价方法在边坡工程中的应用

可拓工程评价方法是在解决矛盾问题的过程中，既可利用物元的可拓性确定定性因素，又可利用可拓集合论，通过关联函数可取负值这一特点进行定量计算，使评价方法能较全面地分析对象属于集合的程度，较好地解决了岩体质量评价中定性与定量因素综合评价的问题。     

沿对角线方向倾倒爆破拆除楼房

在楼房爆破拆除中,根据待拆楼房的围围环境,采用了沿楼房对角线方向定向倾倒拆除的方案,并取得了成功。文中介绍了爆破方案、布孔方法及具体的爆破参数。     

矿地产金融初论

本文从经济学角度认为资金是一种特殊资源，具有引导和配置它资源的作用，一定时期的金融制度决定着资金的运动，并从现代公司制度与金融市场的关系以及矿地产业自身的特点，论述了矿地产金融的客观必要性。认为发展矿地产金融的制约因素是矿地产经济的货币化问题，矿地产经济自身的发展以及矿地产金融市场的培育。最后通过对矿地产业与金融业发展客观要求的分析，认为：矿地产金融的主要形式应是证券化。     

基桩低应变测试数值实验研究

根据动力学基本原理，利用ANSYS有限元程序模拟低应变测试基桩几种典型缺陷的位移时域曲线和速度时域曲线，并据此判断基桩质量取得了良好的效果。