Lysis of human monocytic leukemia cells by extracellular adenosine triphosphate: mechanism and characterization of the adenosine triphosphate receptor

The present study shows that extracellular adenosine triphosphate (ATP) has the capacity to mediate dose-dependent lysis of the monocytic leukemia cell line THP-1. The lysis, assessed by 51Cr release, was found to be selective for ATP, because adenosine diphosphate (ADP) or other nucleotides were less effective in their ability to lyse the cells. The amount of 51Cr released was particularly enhanced by the stimulation of the cells with 1,000 U/mL of interferon gamma (IFN-gamma) for 3 days, and the sensitivity was time and dose dependent. Analysis of the mechanism of lysis indicated that the fully ionized form, ATP4-, mediated the lysis, because the addition of cation chelators or the absence of the divalent cations, Ca2+ and Mg2+, in the culture medium of a 6-hour 51Cr release assay increased the percent specific lysis. Therefore, the ATP receptors on THP-1 cells were classified as P2Z purinoceptors. Moreover, it is shown here that the Ca2+/calmodulin complex plays a role in the regulation of the lysis by extracellular ATP of THP-1 cells, because antagonists of this complex, such as trifluoperazine or KN-62, were found to inhibit the ATP-mediated cell lysis.     

Synthesis, characteristics and oxygen-sensitive properties of SrMgxTi 1 − xO3 nanocrystals

SrMg_xTi_{1 - x}O₃ nanocrystals (x = 0.1–0.6) were synthesized by the stearic acid gel method. Powder samples were characterized by X-ray diffraction and X-ray photoelectron (XP) spectroscopy. The results showed that the lattice parameter a and the O 1s XP spectrum changed not only with the Mg content x but also with the grain size d of the samples. The conductivity of a thick film specimen fabricated on an aluminium oxide wafer was investigated in a nitrogen—oxygen atmosphere.     

MEASUREMENT OF THE SPECIFIC SURFACE AREA OF POWDERS BY THIN LAYER WICKING

The specific surface areas (A) of different clay mineral powders were measured by both the BET method and by thin layer wicking. The values of A for the BET and the wicking experiments coincided within a few percent. Thus, the simple and inexpensive thin layer wicking approach may well suffice to obtain reliable specific surface area values for most powders. From the wicking data it is also possible to obtain a rough estimate of the average particle size.     

Evidence of late palaeozoic thermalwater metallization in South Yongmei Depression

This paper discusses the seafloor thermalwater spout sedimentary activity in South Yongmei Depression according to the following evidences: the Yongmei region was in an extended tectonic environment of metaplateform and locally developed intracontinental rift aulacogen in company with the activity of rich alkali, high potassium volcanics of double-peak type. Several kinds of hydrothermal sedimentary rocks and the ore-bearing sedimentary formations of copper-polymetals, iron and manganese exist in this region with a zoning feature of the seafloor thermalwater spout sedimentation. Project supported by the Science Foundation of NECC for Returns Synopsis of the first author Wu Chengjian, associated professor, born in 1957, majoring in ore deposit and mineralgraphy.     

“镍”催化酰氯和有机锡试剂交叉偶联反应的研究

镍络合物催化酰氯与有机锡试剂交叉偶联合成有机酮的反应,其反应选择性强,反应彻底,转化率高,工艺简单。在有机锡过量的情况下,对不同催化剂的催化活性和包括投料比,反应温度,反应时间,反应溶剂等反应条件进行了考察。     

管外上升R－113流体的沸腾换热试验

详细介绍了Ｒ－１１３流体管外上升流动的沸腾换热试验，包括试验台架、流量计和温度测量的修正，以及试验数据。拟合的换热关系式为ｑ＝５２８（Ｔｗ─Ｔｓ）１．３３。     

An efficient numerical approach, for determining the dispersioncharacteristics of dual-mode elliptical-core optical fibers

Based on vectorial formulations which combine the surface integral equation method and the finite-element method, a novel numerical approach is proposed for calculating the dispersion coefficients of dual-mode elliptical-core fibers with arbitrary refractive index profiles. By differentiating the original formulations involving the propagation constant β and the guided mode fields H_x and H_y once and twice with respect to the normalized frequency V, the new formulations for {dβ/dV, dH_x/dV, dH_y/dV} and for {d²β/dV², d² H_x/dV², d²H_y/dV² } are obtained respectively. Once {β, H_x, H_y } is solved through the eigenvalue procedure which dominates the computing time, only a few matrix manipulations are required to obtain {dβ/dV, dH_x/dV, dH_y/dV} and {d²β/dV², d²H_x/dV² , d²H_y/dV²}. Some numerical examples are examined to see the influence of different refractive index distributions with dips on the dispersions of the four nondegenerate LP ₁₁ modes for elliptical-core fibers     

COIL中BHP浓度对发生O_2(~1△)的影响

本文实验研究了BHP的浓度对产生O2（1△）的影响。实验结果表明：当BHP浓度大于3.5M时，Cl2利用率以及O2（1△）的产率将不依赖于BHP浓度的变化而变化，同时，实验结果表明，使用低浓度的BHP对COIL的操作是可行的。     

用数采器对空压机进行状态监测预报

通过几个典型事例的分析、判断和处理，介绍了该厂怎样利用９１ｌ型数采器对２Ｄ１２—１００／８型空压机运行状态进行监测，以预报早期故障，为设备检修提供指导．     

Temperature dependence of hydrogenated amorphous silicon thin-film transistors

The temperature dependence characteristics of hydrogenated amorphous silicon thin-film transistors were investigated. The results indicate that as the temperature was increased, the threshold voltage and the field-effect mobility were first increased, and then decreased, which may be controlled by different mechanisms at low and high temperatures. In addition, if the temperature was higher than 420 K, the Fermi level was promoted to the degenerate-like states, the current channel always existed due to the temperature effect, and the threshold voltage became negative.