对气体分析仪现状与发展的初步探讨

本文较详细地介绍了氩、氧、水分等几种分析仪器 ,阐述了它们的工作原理、优点、缺点及使用中应注意的问题     

Growth of aluminum nitride thin films prepared by plasma-enhanced atomic layer deposition

Aluminum nitride (AlN) thin films were deposited by atomic layer deposition from aluminum chloride (AlCl₃) and an ammonia/hydrogen plasma. The most important role of the ammonia/hydrogen plasma was to act as a reducing agent to extract Cl from AlCl₃, and to form AlN subsequently. The growth rate was saturated at ∼0.042 nm/cycle, and the thickness was proportional to the number of reaction cycles. Repeating this reaction cycle led to precisely controlled growth. The film properties were analyzed using Auger electron spectroscopy, X-ray photoelectron spectroscopy, Rutherford backscattering spectroscopy and time-of-flight elastic recoil detection analysis. The concentration of chlorine and hydrogen impurities was 0.23 and 2.01 at.%, respectively. AlN films showed good anti-oxidation properties when O₂ was annealed at 650 °C for 30 min.     

关于管理信息化工作的思考

本文探讨在管理信息化工作的关键内容,分析了信息、信息工具与管理工作的关系,强调信息数据的重要性。认为信息是管理工作的主要内容,信息的载体从纸张介质向电磁介质转化,信息工具因此发生了重要变化。管理工作是对工作中产生的信息进行处理,信息量的大小决定了组织结构,信息的如何处理决定了管理的工作流程。管理信息化工作要从信息载体变化的前提出发,考虑这个转变所带来的各种困难,充分应用信息工具的各种资源。在管理信息化工作中应考虑企业的成本和效益。管理系统应从业务出发,打破部门的界限,从数据源头开始,着重考虑权限的榨制,增强灵活性和适应性。     

网络性能分析评价方法及其计算机仿真方法讨论

网络性能分析评价的一般方法包括解析法、数值法和仿真法。仿真法是目前计算机通信网络系统性能分析的主流方法。该文讨论了网络性能分析评价的般方法和局域网网络性能的计算机仿真分析方法,并简要介绍了一个专用网络仿真分析软件。     

Selective Coloration of Melanin Nanospheres through Resonant Mie Scattering

Black melanin inks are prepared to selectively exhibit colors under strong light, inspired by human hair. High absorbance of melanin suppresses multiple scattering, causing resonant Mie scattering predominant. Various colors can be developed as the resonant wavelength dictated by nanosphere diameter. Therefore, the melanin inks can be used to encrypt and selectively disclose multicolor patterns for anticounterfeiting applications.     

Large-scale fabrication of bioinspired fibers for directional water collection

Spider-silk inspired functional fibers with periodic spindle-knots and the ability to collect water in a directional manner are fabricated on a large scale using a fluid coating method. The fabrication process is investigated in detail, considering factors like the fiber-drawing velocity, solution viscosity, and surface tension. These bioinspired fibers are inexpensive and durable, which makes it possible to collect water from fog in a similar manner to a spider's web.     

A Fully-Human Antibody Specifically Targeting a Membrane-Bound Fragment of CADM1 Potentiates the T Cell-Mediated Death of Human Small-Cell Lung Cancer Cells

Small-cell lung cancer (SCLC) is the most aggressive form of lung cancer and the leading cause of global cancer-related mortality. Despite the earlier identification of membrane-proximal cleavage of cell adhesion molecule 1 (CADM1) in cancers, the role of the membrane-bound fragment of CAMD1 (MF-CADM1) is yet to be clearly identified. In this study, we first isolated MF-CADM1-specific fully human single-chain variable fragments (scFvs) from the human synthetic scFv antibody library using the phage display technology. Following the selected scFv conversion to human immunoglobulin G1 (IgG1) scFv-Fc antibodies (K103.1–4), multiple characterization studies, including antibody cross-species reactivity, purity, production yield, and binding affinity, were verified. Finally, via intensive in vitro efficacy and toxicity evaluation studies, we identified K103.3 as a lead antibody that potently promotes the death of human SCLC cell lines, including NCI-H69, NCI-H146, and NCI-H187, by activated Jurkat T cells without severe endothelial toxicity. Taken together, these findings suggest that antibody-based targeting of MF-CADM1 may be an effective strategy to potentiate T cell-mediated SCLC death, and MF-CADM1 may be a novel potential therapeutic target in SCLC for antibody therapy.     

Proteomic Biomarkers of the Apnea Hypopnea Index and Obstructive Sleep Apnea: Insights into the Pathophysiology of Presence,Severity, and Treatment Response

Obstructive sleep apnea (OSA), a disease associated with excessive sleepiness and increased cardiovascular risk, affects an estimated 1 billion people worldwide. The present study examined proteomic biomarkers indicative of presence, severity, and treatment response in OSA. Participants (n = 1391) of the Stanford Technology Analytics and Genomics in Sleep study had blood collected and completed an overnight polysomnography for scoring the apnea–hypopnea index (AHI). A highly multiplexed aptamer-based array (SomaScan) was used to quantify 5000 proteins in all plasma samples. Two separate intervention-based cohorts with sleep apnea (n = 41) provided samples pre- and post-continuous/positive airway pressure (CPAP/PAP). Multivariate analyses identified 84 proteins (47 positively, 37 negatively) associated with AHI after correction for multiple testing. Of the top 15 features from a machine learning classifier for AHI ≥ 15 vs. AHI < 15 (Area Under the Curve (AUC) = 0.74), 8 were significant markers of both AHI and OSA from multivariate analyses. Exploration of pre- and post-intervention analysis identified 5 of the 84 proteins to be significantly decreased following CPAP/PAP treatment, with pathways involving endothelial function, blood coagulation, and inflammatory response. The present study identified PAI-1, tPA, and sE-Selectin as key biomarkers and suggests that endothelial dysfunction and increased coagulopathy are important consequences of OSA, which may explain the association with cardiovascular disease and stroke.     

直流输电系统用直流分压器现场检测方法研究

对直流输电系统中所用直流分压器设备的准确度进行现场检测,目前国内还没有检定规程或校准规范和实施程序。根据现场环境,提出使用桥式电阻分压器自校准的方法,提出现场实施程序,注意事项,主要仪器的选型及误差分析,分析了现场存在的影响因素,以及影响程度,并完成模拟现场环境的验证试验,试验数据表明,该方法及其实施过程符合直流分压器现场检测要求,对现场检测试验具有指导意义,并可为实验室检定提供参考价值。     

动态对抗下捷变频对雷达检测性能的影响及其抗干扰性能度量研究

分析研究了动态对抗情况下捷变频对雷达检测性能的影响,提出了一种雷达捷变频抗干扰性能的度量方法.