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71.
Dr. Manuel Nieto-Domínguez Dr. Pablo I. Nikel 《Chembiochem : a European journal of chemical biology》2020,21(18):2551-2571
The diversity of life relies on a handful of chemical elements (carbon, oxygen, hydrogen, nitrogen, sulfur and phosphorus) as part of essential building blocks; some other atoms are needed to a lesser extent, but most of the remaining elements are excluded from biology. This circumstance limits the scope of biochemical reactions in extant metabolism – yet it offers a phenomenal playground for synthetic biology. Xenobiology aims to bring novel bricks to life that could be exploited for (xeno)metabolite synthesis. In particular, the assembly of novel pathways engineered to handle nonbiological elements (neometabolism) will broaden chemical space beyond the reach of natural evolution. In this review, xeno-elements that could be blended into nature's biosynthetic portfolio are discussed together with their physicochemical properties and tools and strategies to incorporate them into biochemistry. We argue that current bioproduction methods can be revolutionized by bridging xenobiology and neometabolism for the synthesis of new-to-nature molecules, such as organohalides. 相似文献
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75.
Technical Physics Letters - Possible designs of a terahertz laser that use the effect of Bloch oscillations in SiC natural superlattices have been considered. It has been proposed to use as a... 相似文献
76.
J Comas I Rodríguez-Roda M Poch K V Gernaey C Rosen U Jeppsson 《Water science and technology》2006,53(4-5):303-311
Wastewater treatment plant operators encounter complex operational problems related to the activated sludge process and usually respond to these by applying their own intuition and by taking advantage of what they have learnt from past experiences of similar problems. However, previous process experiences are not easy to integrate in numerical control, and new tools must be developed to enable re-use of plant operating experience. The aim of this paper is to investigate the usefulness of a case-based reasoning (CBR) approach to apply learning and re-use of knowledge gained during past incidents to confront actual complex problems through the IWA/COST Benchmark protocol. A case study shows that the proposed CBR system achieves a significant improvement of the benchmark plant performance when facing a high-flow event disturbance. 相似文献
77.
Y S Cao C M Ang K S Raajeevan A K Kiran K C Lai S W Ng I Zulkifli Y L Wah 《Water science and technology》2006,54(8):237-246
This paper analyses the performance of the anaerobic selector (A/O process) in a full-scale activated sludge process receiving mostly industrial sewage discharge (> 60%) in Singapore. In addition to the sludge settleability, enhanced biological phosphorus removal (EBPR) was studied. The sludge volume index (SVI) reduced from 200 to 80 ml g(-1) and foaming was suppressed significantly, indicating the effectiveness of the anaerobic selector in improving sludge settleability. The phosphorus removal efficiency was 66%, and 7.5 mg HAc-COD was consumed per mg PO4(3-) -P removed. In the anaerobic compartment, 31% of the SCOD and 73% of the acetic acid in the settled sewage were removed with PO4(3-) -P release of 14.1 mg PO4(3-)-P l(-1). The linear correlation between PO4(3-) -P release in the anaerobic compartment and PO4(3-) -P uptake in the aerobic compartment indicates that there is about 0.8 mg PO4(3-) -P release in the anaerobic compartment per mg PO34(3-) -P uptake in the aerobic compartment. The fates of volatile fatty acids (VFAs) and its short chain acids (SCAs) in the process were studied and discussed. 相似文献
78.
The main factors that determine the uniformity with which smelting products are tapped from a blast furnace are the rate of accumulation of the products in the hearth and the tapping rate. The first parameter is in turn determined by the stability of the furnace’s operation and can vary significantly even over the course of 24 h. The second parameter is determined mainly by the condition of the iron notch, the maintenance it receives, any changes that occur in the diameter of the channel of the notch, and the quality of the materials used to form the notch. Recommendations are presented to optimize tapping of the smelting products. 相似文献
79.
D. A. Mirzaev N. I. Vorob’ev O. K. Tokovi D. V. Shaburov E. A. Fominykh 《Russian Metallurgy (Metally)》2006,(1):38-41
The solutions to a differential equation for the problem of heating of a cylinder in a medium with a fixed temperature are used to obtain equations for estimating the change in the hydrogen concentration in forgings from data on the hydrogen concentration at the cylinder axis or on the average bulk hydrogen concentration. Similar equations are also obtained for forgings having square cross sections. The calculation demonstrates that, for the case of a twofold decrease in the hydrogen concentration in a forging, the calculated times of annealing of a cylindrical forging differ by three times. 相似文献
80.
P. B. Lovyrev A. I. Lavrov V. A. Babkin A. N. Aminov S. M. Melekhin Yu. P. Kazantsev P. M. Korol’kov 《Metallurgist》2006,50(3-4):152-157
Specifications require that all the welds in 12-m-diam. decomposers with a capacity of 3600 m3 be subjected to high-temperature tempering before going into service in order to alleviate the stresses from the welding
operation. Specialists at the organizations VNIIPTkhimnefteapparatury and VNIImontazhspetsstroi have proposed out-of-furnace
volumetric (complete) of the assembled decomposer with the use of special heaters. The use of this heating method has shortened
assembly operations while providing the welds with a highquality heat treatment and reducing the stresses overall (including
welding stresses, stresses from assembly of the decomposer, etc.) The technology ensures uniform heating of the housing of
the decomposer and provides for close control over the process. The experience gained in heat-treating decomposers can also
be used in the construction of other containers that come into contact with corrosive media.
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Translated from Metallurg, No. 3, pp. 61–64, March, 2006. 相似文献