Thermal design method of bayonet-tube evaporators and condensers

The paper describes an effectiveness-NTU design method of bayonet-tube evaporators and condensers. Including the effect of the wall superheat on the shell-side film coefficient, and using an energy balance on the tube, differential equations for the steady-state fluid temperatures are formulated. Because of the nonlinear nature of the governing equations, the fourth-order Runge-Kutta method is employed to the solution of the finite difference equations. The results are iterated with the combination of integration techniques. An upper bound to the numerical error being ±5% the fluid temperature distribution as well as the exchanger effectiveness are determined, and presented as a function of the Hurd number, the number of heat transfer units and the flow arrangement. For flow entering through the inner tube, the temperature distribution displays the occurrence of a minimum at a point other than the tube-tip of the exchanger. In an extension of the analysis, an effort is made to illustrate the deviation of the results obtained by uniform film coefficient from the present study, and the differences are outlined.     

Detection of Discordant Content Uniformity Observations and Compendial Compliance

A discordant observation is a data point whose value is drastically different from that of the rest of the members in the data set. In the context of content uniformity experiments, however, a discordant observation arises in two ways: (i) when the value of an observation is markedly distant from that of the other data points even though it is within the required compendial range, and (ii) when the value of an observation is outside the permissible compendial range. Several statistical tests for detecting one or more discordant observations are presented. Since discordancy distorts the symmetricity of the data, several tests of symmetricity are provided. Tests for detection of group discordancy induced by discordant samples are also included. The compendial requirements are explained in statistical terms. The impact of discordant observations on compendial compliance requirements is assessed. The statistical basis of the construction of compendial limits as well as the assumptions implicit in the construction is elaborated. The results of the statistical analysis of three content uniformity studies are appropriately interpreted.     

Red blood cell glutathione status in patients with gastrointestinal malignancies treated with 5-fluorouracil

As an alternative to surgical splenectomy, partial splenic embolization was performed in seven children for hypersplenism manifested by splenomegaly, thrombocytopenia, leukopenia, and erythrocyte hemolysis. Within a few days, platelet and leukocyte counts rose significantly in all patients and were maintained in six of seven patients during a follow-up period of 9 to 69 months. Spleen size and abdominal distention also decreased significantly in all children. There were no infectious complications.     

Synthesis and characterisation of carboxylic acid and diphenylphosphine derivatives in the 1,3-diyne series: Spectral properties of polydiacetylene carboxylates

Symmetrically substituted 1,3-diynes containing hydroxyalkyl ( 1a-d ), bromoalkyl ( 1e-h ) (diphenylphosphinyl) ( 1i-k ) and carboxyalkyl ( 2a-d ) substituents have been prepared and characterised; the phosphine derivative ( 1k ) has been converted with alkyl iodides ( RI ; R = Me, Et) into bis(phosphonium) salts ( 1l and m ). During preparation of the diynedioic acid. ( 2a ), the non-centrosymmetrical diyne, HO₂CCH₂C?C—C?C(CH₂)₂OH ( 3 ), was also isolated. ⁶⁰Co γ-Irradiation of diacetylene monomers ( 2a – d ) and 10,12-tricosadiyn-1-oic acid gave the corresponding polydiacetylene derivatives ( 4a – d and 5 ), respectively. Rubidium salts of ( 4c ) and ( 4d ), a barium salt of ( 4c ), and a potassium salt of ( 5 ) were prepared and isolated; soluble potassium salts of the carboxylic acid polymers ( 4 ) were generated in aqueous solution. The effects of changes in pH on the UV/visible absorption spectra of aqueous solutions of selected carboxylic acid polydiacetylenes have been recorded, and are discussed.     

Optical properties and laser performance of neodymium doped fluoroapatites SrxCa5−x(PO4)3F (x = 0, 1, 2, 3, 4, and 5)

Nd doped fluoroapatites Sr_xCa_5−x(PO₄)₃F(S_xC_5−xPF, X = 0, 1, 2, 3, 4, and 5) single crystals have been grown by the Czochralski technique. Their polarized absorption and emission spectra have been recorded at room temperature and used to calculate the absorption and stimulated emission cross sections. Broadening of the absorption and emission bands is observed for Nd³⁺ in the solid solutions SPF-CPF compared to Nd³⁺ in CPF or SPF. 1% Nd:S_xC_5−xPF, X = 0, 2, 3, 4, and 5, laser rods have been tested in a cavity longitudinally pumped by a 1 W AlGaAs laser diode and compared to Nd:YAG and Nd:YVO₄ rods. All fluoroapatites exhibit very good laser performance with low thresholds and high slope efficiencies, higher than in the case of YAG and equal to the YVO₄ samples. The dependance of the laser output power versus the diode temperature has also been measured for all materials. The laser output was found to be as sensitive to the diode temperature fluctuations for fluoroapatites as for YAG.     

The As-prepared surfaces of C-axis-oriented Nd1Ba2Cu3Oy thin films characterized using scanning probe microscopes

Recently, superconducting Nd₁Ba₂Cu₃O_y (Ndl23) thin films with high superconducting transition temperature (T _c) have been successfully fabricated at our institute employing the standard laser ablation method. In this paper, we report the results of surface characterization of the Nd123 thin films using an ultrahigh vacuum scanning tunneling microscope/spectroscopy (UHV-STM/STS) and an atomic force microscope (AFM) system operated in air. Clear spiral pattern is observed on the surfaces of Nd123 thin films by STM and AFM, suggesting that films are formed by two-dimensional island growth mode. Contour plots of the spirals show that the step heights of the spirals are not always the integer or half-integer number of thec-axis parameter of the structure. This implies that the surface natural termination layer of the films may not be unique. This result is supported byI-V STS measurements. The surface morphology of the Nd123 thin films is compared with that of thec-axis-oriented Y₁Ba₂Cu₃S_y thin films. Surface atomic images of the as-prepared Nd123 thin films are obtained employing both STM and AFM. STS measurements show that most of the surfaces are semiconductive. The results of STS measurements together with the fact that we are able to see the surface atomic images using scanning probe microscopes suggest that exposure to air does not cause serious degradation to the as-prepared surfaces of Nd123 thin films.     

An assessment of the θ-projection method for the representation and extrapolation of creep data for a 1%Cr, 12%Mo, 14%V steel tested at 565°C

Constant stress creep data for a wrought 1%Cr, $\text{1}\text{2}\text{\%}\text{Mo}$, $\text{1}\text{4}\text{\%}\text{V}$ steel obtained from six tests carried out at 565°C have been fitted and extrapolated using the θ-projection method. Creep curves for high stresses were fitted well, but curves extrapolated to stress levels below those used in the θ-projection did not represent well the available data for primary-secondary creep. To enable a satisfactory extrapolation of results, it was found necessary to redefine the failure condition to be less sensitive to the shape of the latter sections of the tertiary creep curve. This was achieved by defining lifetime as the point on the curve at which the strain rate reached a fixed multiple of the creep rate at half the rupture time. The extrapolated data compare well with the results of tests carried out independently on a cast 1%Cr, $\text{1}\text{2}\text{\%}\text{Mo}$, $\text{1}\text{4}\text{\%}\text{V}$ steel. The extrapolation procedure not only predicts the ‘knee’ in the log stress-log lifetime curve but allows extrapolation of lifetimes by over a factor of thirty. In addition, acceptable predictions have been made of constant load experimental data.     

Surface tension isotherms of a free surface and grain boundaries in the Cu-Sn system

Surface tension of pure copper and its alloys with Sn has been measured at 1000°C in a hydrogen atmosphere. Surface tension of a free surface equaled 1.81 N/m for pure copper, and 1.55, 1.38, and 1.28 N/m for the alloys with 0.05, 0.22, and 0.33 at % Sn, respectively; surface tension at grain boundaries equaled 0.5 N/m for pure copper, and 0.36, 0.3, and 0.23 N/m for the alloys, respectively. Based on these data, the concentration dependence of tin absorption at a free surface and grain boundaries has been calculated. Parameters of Sn absorption at grain boundaries and a free surface of copper have been compared with those of Sb and Bi.