线型双酚A酚醛树脂的合成

对线型双酚A酚醛树脂的合成工艺及催化剂浓度、种类、反应时间、醛酚比等影响因素进行了研究。结果表明,随着反应物醛酚比的增大,产物中残留的BPA量呈下降趋势,软化点先上升后下降,在1.2左右出现峰值;随反应时间延长,产物的软化点升高,分子质量增大,残留BPA量减少,分子质量分散性增加;催化剂用量增大,分子质量增大,软化点增高,残留BPA含量降低。合理的催化剂用量为m(BPA)∶m(催化剂)=100∶20。以合成的BPAN代替双氰胺(D ICY)作环氧树脂EB454A80的固化剂,在相同的固化工艺条件下,固化物的Tg提高近12℃。     

Comprehensive Integrated Single-Cell Whole Transcriptome Analysis Revealed the p-EMT Tumor Cells—CAFs Communication in Oral Squamous Cell Carcinoma

Cancer-associated fibroblasts (CAFs) and partial epithelial–mesenchymal transition (p-EMT) tumor cells are closed together and contribute to the tumor progression of oral squamous cell carcinoma (OSCC). In the present study, we deeply analyzed and integrated OSCC single-cell RNA sequencing datasets to define OSCC CAFs and p-EMT subpopulations. We highlighted the cell–cell interaction network of CAFs and p-EMT tumor cells and suggested biomarkers for the diagnosis and prognosis of OSCC during the metastasis condition. The analysis discovered four subtypes of CAFs: one p-EMT tumor cell population, and cycling tumor cells as well as TNFSF12-TNFRSF25/TNFRSF12A interactions between CAFs and p-EMT tumor cells during tumor metastasis. This suggests the prediction of therapeutically targetable checkpoint receptor–ligand interactions between CAFs and p-EMT tumor cells in OSCC regarding the metastasis status.     

Comprehensive Analysis of hsa-miR-654-5p’s Tumor-Suppressing Functions

The pivotal roles of miRNAs in carcinogenesis, metastasis, and prognosis have been demonstrated recently in various cancers. This study intended to investigate the specific roles of hsa-miR-654-5p in lung cancer, which is, in general, rarely discussed. A series of closed-loop bioinformatic functional analyses were integrated with in vitro experimental validation to explore the overall biological functions and pan-cancer regulation pattern of miR-654-5p. We found that miR-654-5p abundance was significantly elevated in LUAD tissues and correlated with patients’ survival. A total of 275 potential targets of miR-654-5p were then identified and the miR-654-5p-RNF8 regulation axis was validated in vitro as a proof of concept. Furthermore, we revealed the tumor-suppressing roles of miR-654-5p and demonstrated that miR-654-5p inhibited the lung cancer cell epithelial-mesenchymal transition (EMT) process, cell proliferation, and migration using target-based, abundance-based, and ssGSEA-based bioinformatic methods and in vitro validation. Following the construction of a protein–protein interaction network, 11 highly interconnected hub genes were identified and a five-genes risk scoring model was developed to assess their potential prognostic ability. Our study does not only provide a basic miRNA-mRNA-phenotypes reference map for understanding the function of miR-654-5p in different cancers but also reveals the tumor-suppressing roles and prognostic values of miR-654-5p.     

钨镍共掺杂V2O5薄膜的光电特性研究

利用溶胶–凝胶旋涂法和后退火工艺在FTO导电玻璃上制备了钨镍共掺杂V₂O₅薄膜,研究了薄膜在不同温度和不同偏压下的光电特性和相变特性。利用X射线衍射仪（XRD）、扫描电子显微镜（SEM） 和X射线光电子能谱仪（XPS） 测试了钨镍共掺杂V₂O₅薄膜的晶体结构、表面形貌和组分,分析了不同钨镍共掺杂浓度对V₂O₅薄膜相变光电特性的影响。结果表明,当钨和镍的掺杂质量分数分别为3 %和1.5 %时,钨镍共掺杂的V₂O₅薄膜的相变温度为218.5 ℃,在可见光范围内有较高的透过率,在近红外1310 nm波长处的光学透过率达48.83%,与未掺杂V₂O₅薄膜的光学透过率相比提高了10.29%,薄膜电阻降低了30.53%,热致回线宽度收窄为15 ℃,说明钨镍共掺杂的V₂O₅薄膜具有良好的可逆相变光电特性,有望在新型光电器件领域得到较好的应用。     

城市空间扩张及结构演化的制度因素分析

改革开放以来,中国城市的发展环境发生了巨大的变迁,制度力成为深刻影响城市空间扩张与结构演变的关键因素。在转型期,中国只有加快推进地方政府企业化治理体系,土地制度、土地规制等相应的制度性变革,才是实现城市空间的集约增长、理性增长和结构优化的根本之策。     

基于局部变分贝叶斯推断的分布式交互式多模型估计

针对目前部分多模型算法预先设定运动模型转移概率矩阵对状态估计精度的不利影响,本文提出了一种基于局部变分贝叶斯推断的分布式交互式多模型估计算法.不同于传统交互式多模型估计中运动模型转移概率矩阵为先验已知的假设条件,在分布融合估计框架下,首先基于最小化Kullback-Leibler散度准则的递归优化策略实现对运动模型转移概率矩阵的预测与更新;在此基础上,结合变分贝叶斯推断实现对当前时刻目标状态与模型概率的联合估计;最后依据协方差交叉融合策略完成对局部状态估计融合.仿真结果表明:新算法通过对运动模型转移概率矩阵以及模型概率自适应在线估计,有效提升了机动目标的状态估计精度.     

Blue Luminescence of ZnO Nanoparticles Based on Non‐Equilibrium Processes: Defect Origins and Emission Controls

High concentrations of defects are introduced into nanoscale ZnO through non‐equilibrium processes and resultant blue emissions are comprehensively analyzed, focusing on defect origins and broad controls. Some ZnO nanoparticles exhibit very strong blue emissions, the intensity of which first increase and then decrease with annealing. These visible emissions exhibit strong and interesting excitation dependences: 1) the optimal excitation energy for blue emissions is near the bandgap energy, but the effective excitation can obviously be lower, even 420 nm (2.95 eV < E_g = 3.26 eV); in contrast, green emissions can be excited only by energies larger than the bandgap energy; and, 2) there are several fixed emitting wavelengths at 415, 440, 455 and 488 nm in the blue wave band, which exhibit considerable stability in different excitation and annealing conditions. Mechanisms for blue emissions from ZnO are proposed with interstitial‐zinc‐related defect levels as initial states. EPR spectra reveal the predominance of interstitial zinc in as‐prepared samples, and the evolutions of coexisting interstitial zinc and oxygen vacancies with annealing. Furthermore, good controllability of visible emissions is achieved, including the co‐emission of blue and green emissions and peak adjustment from blue to yellow.     

Transition Motion from Ladder Climbing to Brachiation with Optimal Load-Allocation Control

Abstract

This paper describes the transition motion from ladder climbing to brachiation for a multi-locomotion robot (MLR). The MLR has versatile modes of locomotion, such as biped walking, quadruped walking, brachiation and ladder climbing. The transition is a challenging motion, because the environmental boundaries change and the robot has to switch the form of its locomotion depending on its surroundings, situations and purposes. The robot supports itself with three end-effectors that maintain its stability, while one hand transfers from a rung on the vertical ladder to a new rung behind the robot for brachiation. A closed kinematic chain is formed by the robot links and the ladder. In this case, if the number of position-controlled active joints is greater than the number of the chain’s degrees of freedom, an internal stress appears because of unavoidable position errors. The huge internal stress may lead some motors to become overloaded. Since the safety of each motor is very important for a serial-link robot, a load-allocation algorithm is proposed to balance the loads of the joint motors. The algorithm is verified through experiments.     

一种可快速生成虚拟培训系统

本文介绍的虚拟实务培训系统基于有限状态机思想,利用状态跳转的思想简化虚拟培训系统的实现逻辑,并选用FLEX、数据库技术对系统在技术上进行了实现。