两种新型含硅植物生长调节剂的合成及其生物活性

合成了2种新型含硅植物生长调节剂。它们的结构经元素分析、IR和^1HNMR表征。生物活性试验表明,药液质量浓度为25mg/L时,2种目标化合物对水稻根生长比对照化合物1-萘乙酸乙基二甲硅基酯分别提高了10%和13%。     

二丁基(三甲基硅基亚甲基)锡芳香酸酯的合成、结构及生物活性

合成了9个二丁基(三甲硅基亚甲基)锡芳香酸酯,通过IR、NMR和MS对目标化合物的结构进行了表征.生物活性测定的初步结果表明,该类化合物具有较好的杀螨活性和一定的杀菌活性.     

含硅二烃基锡二吡啶羧酸酯的合成与结构表征

采用含硅二烃基锡氧化物和相应的吡啶甲酸,合成了7个新的含硅二烃基锡配合物--标题化合物;通过IR、1HNMR、13CNMR和元素分析对它们的结构进行表征.生物活性测定的初步结果表明,目标化合物环已基(三甲基硅基亚甲基)锡二(2-吡啶羧酸酯)Cy(Me3SiCH2)Sn(OCOC5H4N-o)2对肺癌细胞A549和肠癌细...     

杂氮硅三环化合物的合成与生物活性

综述了近10年来杂氮硅三环化合物的合成方法和生物活性研究进展，并简要介绍了生物活性和化合物结构的关系。     

具有生物活性的三烃基锡化合物的研究进展

主要对具有生物活性的三烃基锡化合物的研究进行回顾,其中包括不具有含硅基团的单一三烃基锡化合物、混合三烃基锡化合物,具有含硅基团的单一三烃基锡化合物、混合三烃基锡化合物,以及其它结构类型的三烃基锡化合物的生物活性研究。     

杂氮硅三环化合物

杂氮硅三环是一类具有特殊分子结构和显著生物活性的有机硅化合物，其研究进展迅速，而且越来越受到人们的重视，本文杂氮硅环三环化合物的合成、结构、生物活性及应用情况作了简要的论述。     

杂氮硅三环化合物

杂氮硅三环是一类具有特殊分子结构和显著生物活性的有机硅化合物，其研究进展迅速，而且越来越受到人们的重视。本文对杂氮硅三环化合物的合成、结构、生物活性及应用情况作了简要的论述     

肟醚(酯)农药活性化合物的研究与开发进展

概述了具有虫、菌、草等广谱生物活性的肟醚(酯)化合物，重点介绍了具有肟醚(酯)结构农药的研究与开发进展以及其结构特点和活性特点，并对肟醚(酯)化合物的几何异构与其生物活性的关系及几何异构体的相互转化进行了简述。     

环氧硅酸酯的合成研究

直接从SiO2 (白炭黑 )制备了高活性的五配位硅化合物 ,并用带环氧官能团的含卤化合物与活性五配位硅作用 ,衍生出带有环氧官能团的硅酸酯。借助于X 衍射法测试手段 ,对合成产物进行了分析。结果表明 ,高活性的五配位硅呈强碱性 ,吸水性强 ,吸收水分后很快分解还原成SiO2 和有机物。而在含卤化合物与活性五配位硅化合物作用生成硅酸酯后 ,即控制和消除了这种可逆反应 ,制备出了稳定的环氧硅酸酯。     

具有生物活性的有机硅化合物及应用

简要介绍了具有生物活性的有机硅低聚体及硅烷类，聚硅氧烷，有机碳化合物的硅衍生物，特殊结构的有机硅化合物的研究进展。     

含腙类结构化合物生物活性研究进展

含腙类结构的化合物具有杀虫、杀菌、除草等广泛生物活性,在新农药创制中占有重要地位.根据农药用途进行分类,对其生物活性进行了介绍,并对其发展前景作进一步展望.     

含1,2,3-三氮唑肉桂酸衍生物的合成

1,2,3-三氮唑环作为药效基团呈现出多种生物活性,以4-硝基苯甲醛为原料,合成了叠氮基肉桂酸,并以此为原料,CuI为催化剂,与端基炔烃进行1,3-偶极环加成反应,合成含1,2,3-三氮唑功能基的肉桂酸衍生物。     

含吡啶的strobilurin类化合物的研究进展——肟醚乙酸酯和肟醚乙酰胺类

本文简要叙述了含肟醚乙酸酯和肟醚乙酰胺的吡啶strobilurin类化合物近年来的研究进展，主要介绍其化学结构和生物活性。     

偕二金属有机试剂与氯化三烷基锡和碘的非对映选择性反应

研究了偕二金属有机试剂３与氯化三烷基锡和碘的非对映选择性反应，反应表现出高度的非对映立体选择性，以１为基准（５步反应）的产率优良，提出了可能的反应机理。     

含1,2,3-三氮唑哌啶衍生物的合成

1,2,3-三氮唑环作为药效基团呈现出多种生物活性,以六氢吡啶和环氧氯丙烷为底物,在微波辐射条件下,合成了叠氮基哌啶,并以此为原料,CuI为催化剂,MeCN-H2O(10∶1,v/v)为混合溶剂,与端基炔烃进行1,3-偶极环加成反应,合成含1,2,3-三氮唑功能基的哌啶衍生物,收率70%,其结构经核磁共振谱表征。     

Synthesis and Characterization of New Functional Polystyrenes Containing Tributyltin Carboxylate Moieties Linked to the Aromatic Ring by a Trimethylene Spacer

A novel trialkyltin carboxylate monomer, tributyltin 4-(p-styryl)-butanoate, characterized by the presence of a trimethylenic spacer linking the tin carboxylate moiety to the aromatic group, has been prepared and submitted to radical homo- and copolymerization with styrene in order to obtain the corresponding copolymers with variable contents of organometallic moiety. For the sake of comparison, tributyltin 4-(4-isopropylphenyl)-butanoate has also been synthesized as the structural model of the repeating unit of the polymers. All the products prepared have been characterized both in solution and in the solid state by spectroscopic and thermal techniques with the aim to establish the coordination state of the tin atom, a feature which is of importance for future application of these derivatives.     

Effect of the formulation of 2 diets of rats, with wheat bran as a source of dietary fiber, on various biochemical and nutritional parameters

The type of diet formulation was considered in our study on the effects of wheat bran on some parameters obtained in a biological assay, for 28 days. Weanling, male Holtzman rats were divided in three groups. Two of them were fed ad libitum on diets containing 25% of wheat bran, prepared in two ways: balanced (FB) and conventional (FC). In the first case, the fiber source was added at the expense of every other ingredient, whereas in the second, only of starch. The control group received a wheat bran-free diet. Comparison among the groups showed the highest weight gain for group FB, and the lowest protein efficiency ratio (PER) for group FC. Fecal weight and the weight of the cecal contents were significantly higher for the test groups. Mean activity of the alkaline phosphatase from the jejunal mucosa was lower in group FB than in the other two. The activities of this enzyme in serum, were significantly higher for groups FB and FC. Serum cholesterol level was slightly lower for the group fed the balanced diet, than for the one receiving the conventional diet. Therefore, some parameters such as weight gain, PER, alkaline phosphatase activity of the intestinal mucosa, and serum cholesterol, were influenced by the type of diet formulation. Nevertheless, these results are not enough to substantiate a conclusive answer to the question: which diet formulation is more adequate for biological assays, when using wheat bran as a fiber source?     

Synthesis and biological activity of natural thiazoles: An important class of heterocyclic compounds

The class of heterocyclic compounds known as thiazole is found in many natural and synthetic products with a wide range of pharmacological activities, such as antiviral, anticancer, antibacterial, antifungal, anticonvulsant, antiparkinsonian and anti-inflammatory activities that can be well illustrated by the large number of drugs in the market containing this function group. Due to its importance, the aim of this review is to highlight the synthesis and biological activity of the thiazole natural products reported between 2000 and 2004.     

含1,3,4-噻二唑的噻吩类化合物的合成与杀菌活性研究

设计并合成了8个未见报道的含1,3,4-噻二唑的噻吩类化合物6a~6h,其结构经1H NMR、13C NMR、MS、IR分析确证。初步生物测试结果表明:目标化合物对黄瓜灰霉病、水稻纹枯病、马铃薯晚疫有一定的抑制作用。