一种双稳态电磁型射频MEMS开关的设计与测试

设计了一种低电压驱动的双稳态电磁型射频MEMS开关.与驱动电压高这几十伏的静电型射频MEMS开关相比,其驱动电压可低至几伏,因此应用时无需增加电荷泵等升压电路.开关可在磁场驱动下实现双稳态切换,稳态时无直流功率消耗.分析了工作磁场的分布特点,进行了结构设计仿真;并使用HFSS软件和粒子群算法进行了射频参数仿真、结构参数优化及主要结构参数显著性研究,得出了影响开关射频传输性能的主要结构参数;采用表面牺牲层工艺制作了原理样机并进行了射频性能参数的测试.结果表明,开关样机在DC～3 GHz工作频率区间内,插入损耗小于0.25 dB,隔离度大于40 dB.     

NUMA结构的高效实时稳定的垃圾回收算法

针对非一致性内存访问架构(NUMA)在垃圾回收(GC)过程中存在大量的远程内存读写导致GC性能降低的问题,对GC过程的各个阶段进行分析与研究,提出了一种基于NUMA结构的高效实时稳定的GC算法。该算法首先基于NUMA结构改进传统分代GC机制的堆空间布局,然后通过控制GC过程中扫描活跃对象阶段的初始根对象选取、动态负载均衡阶段截取任务队列的选取以及复制活跃对象阶段对象复制位置的选取,大大减少GC过程中的远程访问次数。这种改进的GC机制对所有NUMA结构具有通用性。以Godson-3处理器的NUMA平台为例进行的实验结果显示,优化的GC机制极大地缩短了GC的时间,而且提高了应用程序的性能以及稳定性。在SPECjvm2008测试中,GC时间平均缩短了14.6%(GC总时间缩短4.1%~41.58%),应用程序的性能平均提升了4.68%(最高提升17.8%),应用程序的性能稳定性提升了76.2%。     

Development and Validation of an Artificial Mechanical Skin Model for the Study of Interactions between Skin and Microneedles

Microneedles are small needle‐like structures that are almost invisible to the naked eye. They have an immense potential to serve as a valuable tool in many medical applications, such as painless vaccination. Microneedles work by breaking through the stratum corneum, the outermost barrier layer of the skin, and providing a direct path for drug delivery into the skin. A lot of research has been presented over the past two decades on the applications of microneedles, yet the fundamental mechanism of how they interact, pressure, and penetrate the skin in its native state is worth examining further. As such, a major difficulty with understanding the mechanism of microneedle–skin interaction is the lack of an artificial mechanical human skin model to use as a standardized substrate. In this research news, the development of an artificial mechanical skin model based on a thorough mechanical study of fresh human and porcine skin samples is presented. The artificial mechanical skin model can be used to study the mechanical interactions between microneedles and skin, but not diffusion of molecules across skin. This model can assist in improving the performance of microneedles by enhancing the reproducibility of microneedle depth insertions for optimal drug delivery and biosensing.

     

高速铁路声屏障几何形状声学性能数值模拟

为了弄清声屏障几何形状对高速铁路户外噪声的降噪机理和降噪效果,采用二维边界元法建立高架桥铁路声屏障噪声预测模型,分析不同几何形状结构参数对降噪性能的影响。分析中考虑列车运行速度、声源分布及频谱特性对插入损失的影响,根据车外声源识别结果建立符合我国高速铁路的声源模型;考虑车体-轨道-声屏障之间的多重反射,建立边界元计算模型;对顶部倾斜、T型、多重绕射边型、Y型、圆柱型等声屏障的结构参数的影响进行调查分析,分析中分别考虑插入损失、场点频谱及声场变化规律。研究结果表明,Y型声屏障降噪效果最好,平均插入损失提高3.4 dB(A)其次为圆柱型声屏障。     

提高127V照明信号综合保护装置使用寿命的探讨

通过对三相综合保护装置带负载能力及其损耗的分析，阐述了降低该装置使用寿命和可靠性的原因，并提出了解决方法。     

一种基于累加支路辅助的上面级跟踪切换方案

为了满足火箭上面级测控下行信息量增大的特殊要求,借鉴等时性插入业务的思想设计了一种新的适应于上面级测控的信息帧格式。在此基础上,提出了这种帧格式下的跟踪方案,设计利用二阶环路滤波器累加支路输出辅助伪码跟踪环与位同步环的切换。根据推导出的比例因子,仿真了其性能。仿真结果表明,这种切换方式可以实现平滑过渡,性能良好。     

声屏障声学特性的模型试验研究

应用因次分析法确定声屏障实验室模型试验相似准数,通过模型试验测量声屏障插入损失并与目前工程中常用公式预估结果比较表明,模型与实物之间的声学特性关系可以用相似法准则进行定量描述,其结论对于进行声屏障声学设计有重要参考价值。     

Deletion and insertion of a 192-residue peptide in the active-site domain of glycosyl hydrolase family-2 beta-galactosidases

The monomeric multimetal-binding beta-galactosidase of Saccharopolyspora rectivirgula (srbg), a glycosyl hydrolase family-2 enzyme, has a unique sequence consisting of 192 amino acid residues with no similarity to known proteins. This 192-residue sequence (termed the "iota [iota] sequence") appears to be inserted into a sequence homologous to the active-site domain of the Escherichia coli lacZ enzyme (lacZbg). To assess the effects of the t sequence at specific sites of beta-galactosidase on the catalytic functioning and molecular properties of beta-galactosidase, deletion or insertion mutants of beta-galactosidases were constructed, expressed in LacZ- E. coli strains, and characterized: srbgdelta in which the iota sequence was deleted from srbg, and lacZbgI, in which the 192-residue iota sequence was inserted into the corresponding position (between Asp591 and Phe592) in the active-site domain of lacZbg. srbgdelta was a catalytically inactive, dimeric protein which retained multimetal-binding characteristics, suggesting that the iota sequence is very important for maintaining the structure necessary for the catalytic functioning and the monomeric structure of srbg but is not responsible for the unique metal ion requirements of srbg. On the other hand, lacZbgI existed as a mixture of a monomer, a tetramer, and higher multimers. The monomeric species was inactive, whereas the tetramer and other multimers were catalytically active (V(max )K(m) value, 25% of that of lacZbg) and highly specific for beta-D-galactoside. The tetrameric lacZbgI was activated by Mg2+ and Mn2+ with lowered metal affinities, and the stoichiometry of metal binding was unchanged from that of lacZbg. These results, along with the published stereo structure of lacZbg, suggest that, in lacZbgI, the inserted 192-residue iota peptide could fold independently of the lacZbg domains into a "sub-domain," lying distant from the active site and subunit interfaces.     

门式刚架轻型房屋钢结构设计中应注意的几个问题

轻钢结构近年来在我国得以广泛应用，但由于各种原因造成事故时有发生．根据实际情况，总结多年的设计经验，提出在设计中应注意活荷载选取、材料选取、跨度选取、隅撑布置等方面的建议，供设计同仁们参考．     

基于P2P系统应用层组播在流媒体中的应用

由于live流是一种高带宽的应用，甚至当为数不多的客户同时采用单播从一个源请求流时，也可以使服务器的带宽饱和。作为有效解决方法的IP组播因为缺乏广泛的支持而逐渐被应用层组播代替。本文在peer-to-peer系统上采用以树为基础的应用层组播结构，实现用客户自己的带宽传输流媒体以缓解服务器附近的拥塞问题。在该结构中，每个客户peer端在应用层与传输层之间加入peering层，实现结点之间的协调和建立、维护组播树。